Protein
MCA_02498_1
Length
375 amino acids
Gene name: ARO4
Description: Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited
Browser: contigB:1481079-1482359-
RNA-seq: read pairs 4758, FPKM 156.4, percentile rank 85.3% (100% = highest expression)
Protein function
| Annotation: | ARO4 | Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited | |
|---|---|---|---|
| KEGG: | K01626 | E2.5.1.54 | 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] |
| EGGNOG: | 0PG9I | ARO4 | Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) |
| SGD closest match: | S000000453 | ARO4 | Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited |
| CGD closest match: | CAL0000182853 | ARO4 | Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02818_1 | 82.56% | 367 | 0.0 | MIA_02818_1 |
| A0A0J9X880_GEOCN | 76.00% | 375 | 0.0 | Phospho-2-dehydro-3-deoxyheptonate aldolase OS=Geotrichum candidum GN=BN980_GECA05s00472g PE=3 SV=1 |
| A0A167CTQ0_9ASCO | 75.81% | 372 | 0.0 | Phospho-2-dehydro-3-deoxyheptonate aldolase OS=Sugiyamaella lignohabitans GN=ARO4 PE=3 SV=1 |
| A0A1E3PIC7_9ASCO | 71.85% | 373 | 0.0 | Phospho-2-dehydro-3-deoxyheptonate aldolase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52319 PE=3 SV=1 |
| Q6CCS4_YARLI | 76.30% | 346 | 0.0 | Phospho-2-dehydro-3-deoxyheptonate aldolase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C06952g PE=3 SV=1 |
| A0A060T1R8_BLAAD | 72.63% | 369 | 0.0 | Phospho-2-dehydro-3-deoxyheptonate aldolase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A02310g PE=3 SV=1 |
| A0A1E4TE89_9ASCO | 70.38% | 368 | 0.0 | Phospho-2-dehydro-3-deoxyheptonate aldolase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26502 PE=3 SV=1 |
| AROG_YEAST | 68.53% | 375 | 0.0 | Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARO4 PE=1 SV=2 |
| UniRef50_P32449 | 68.53% | 375 | 0.0 | Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited n=1459 Tax=cellular organisms TaxID=131567 RepID=AROG_YEAST |
| AROG_CANAL | 66.76% | 358 | 2e-175 | Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ARO4 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1236
Protein family membership
- DHAP synthase, class 1 (IPR006219)
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
375
Detailed signature matches
-
-
-
PIRSF001361 (DAHP_s...)
-
-
-
PF00793 (DAHP_synth_1)
-
no IPR
Unintegrated signatures
-
SSF51569 (Aldolase)
-
mobidb-lite (disord...)
Protein sequence
>MCA_02498_1 MSNSPMFKADGLSRNQSPSAEQESEDVRILGYDPLLPPALLQTELPPTRNGLLTVQKGRKEAVDVLNGKSDKVLCIVGPC SIHDSEMAKDYARRLKELSNKLSDDLVVIMRAYLEKPRTTVGWKGLINDPDVDESFNINKGLRISRKLFTELTDMGLPIA SEMLDTISPQFLADLLSLGAIGARTTESQLHRELASGLSFPIGFKNGTDGSVKVAIDAVGAASHSHHFMGVTKQGLAAIT LTKGNDSCFIILRGGTKGPNYDAESVAAVKKELKDNKIPIMIDCSHGNSNKDYRNQPKVLESVAEQIANGEDQVIGVMIE SNINEGAQKVGPEGKKGLKYGVSITDACVGWDTTVDMLEKLAASVRARRAAKNKA
GO term prediction
Biological Process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
Molecular Function
GO:0003824 catalytic activity
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
Cellular Component
None predicted.