Protein

MCA_02491_1

Length
712 amino acids

Gene name: POX1A

Description: Acyl-coenzyme A oxidase

Browser: contigB:1465147-1467286+

RNA-seq: read pairs 6510, FPKM 112.8, percentile rank 80.7% (100% = highest expression)

Protein function

Annotation:POX1AAcyl-coenzyme A oxidase
KEGG:K00232E1.3.3.6 acyl-CoA oxidase [EC:1.3.3.6]
EGGNOG:0PGSVPOX1acyl-Coenzyme A oxidase
SGD closest match:S000003173POX1Acyl-coenzyme A oxidase
CGD closest match:CAL0000183638POX1-3Acyl-coenzyme A oxidase

Protein alignments

%idAln lengthE-value
MIA_01755_180.89%6960.0MIA_01755_1
A0A0J9XHF1_GEOCN65.87%7150.0Acyl-coenzyme A oxidase OS=Geotrichum candidum GN=BN980_GECA14s03310g PE=3 SV=1
A0A0B5AI46_BLAAD62.75%6980.0Acyl-coenzyme A oxidase OS=Blastobotrys adeninivorans PE=3 SV=1
A0A167F3K6_9ASCO60.98%7150.0Acyl-coenzyme A oxidase OS=Sugiyamaella lignohabitans GN=POX1 PE=3 SV=1
ACOX2_YARLI62.07%6960.0Acyl-coenzyme A oxidase 2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=POX2 PE=1 SV=1
A0A1E3PRP2_9ASCO58.60%7150.0Acyl-coenzyme A oxidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81098 PE=3 SV=1
UniRef50_O7493657.99%6880.0Acyl-coenzyme A oxidase 3 n=17 Tax=Saccharomycetales TaxID=4892 RepID=ACOX3_YARLI
A0A1E4TM74_9ASCO50.60%6720.0Acyl-coenzyme A oxidase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_23240 PE=3 SV=1
Q5AJD9_CANAL43.00%6791e-172Acyl-coenzyme A oxidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=POX1-3 PE=3 SV=1
ACOX_YEAST39.20%7221e-151Acyl-coenzyme A oxidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=POX1 PE=3 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0759

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 712

Detailed signature matches

  1. Family IPR012258
    Acyl-CoA oxidase
    1. PIRSF000168 (Acyl-C...)
  2. Domain IPR009100
    Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain
    1. SSF56645 (Acyl-CoA ...)
  3. Domain IPR013786
    Acyl-CoA dehydrogenase/oxidase, N-terminal
    1. G3DSA:1.10.54...
  4. Domain IPR029320
    Acyl-coenzyme A oxidase, N-terminal
    1. PF14749 (Acyl-CoA_ox_N)
  5. Domain IPR006091
    Acyl-CoA oxidase/dehydrogenase, central domain
    1. PF02770 (Acyl-CoA_dh_M)
  6. Domain IPR009075
    Acyl-CoA dehydrogenase/oxidase C-terminal
    1. PF00441 (Acyl-CoA_dh_1)
    2. SSF47203 (Acyl-CoA ...)
  7. Domain IPR002655
    Acyl-CoA oxidase, C-terminal
    1. PF01756 (ACOX)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.20.14...
  3. G3DSA:2.40.11...
  4. mobidb-lite (disord...)

Protein sequence

>MCA_02491_1
MSSPSDRLKNLALNPSSSAINPESTNFATEPPVVMANERSKASFNIRDLTYYLDGGEENTKNIEDIMTSIERDPLFNNDD
YYDLTKDQLRELTVQRVASLASHVAKSPQILHKRFALTAIADPGSGTRTGVHYGLFLGSVRGSGTPEQFSYWVNKGAISL
KRFFGCFGMTELGHGSNVAGLETTATFDEESDEFIIHTPNLAATKWWIGGAAHTATHTVCFARLIIKGKDYGVKSFVVPL
RNTDDWSLKPGVAIGDIGKKMGRDGIDNGWIQFTNVRIPRQFMLMRFSKVDREGNVTEPPLAQLAYGALITGRVSMASDS
FYAASRFLTIAIRYAAVRRQFSTNPGEKENVILDYPLHQRRLLPRLAYTYAMNAAAAQLYEQYETASSQLETVDTSDKKA
LAAAVNDIKELFATSAGVKSFCTWAASDIIDECRQACGGHGYSGYNGFGQGYNDWVVNCTWEGDNNILTLSMGRSLIQSA
VAASKGKKLGAASEYLNRYDTLKNARLNGRSLEDPKVLVEAWESASSILLMNAAVAYERELKKANGNVTAAMEKVSQQRY
ETARVHTRLHLIKSFYNRIAEASKQGTKSETIQILTVVATLFALWSIEQDSGLFLRSRFLAPEDLDNVTALVDEYNAKVR
EQAIPLTDAFNYSDYFINSPIGNYDGNVYKHYFEKVVRRNPNHTSMAPYFDRLAKPFFFRKDEEQINPTDLE

GO term prediction

Biological Process

GO:0006631 fatty acid metabolic process
GO:0006635 fatty acid beta-oxidation
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0003997 acyl-CoA oxidase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
GO:0071949 FAD binding

Cellular Component

GO:0005777 peroxisome