MCA_02483_1

Protein

Length

1,906 amino acids

Gene name: FKS1A

Description: 1,3-beta-glucan synthase component FKS1

Browser: contigB:1447953-1453674-

RNA-seq: read pairs 412, FPKM 2.7, percentile rank 13.2% (100% = highest expression)

Protein function

Annotation:		FKS1A	1,3-beta-glucan synthase component FKS1
KEGG:	K00706	E2.4.1.34	1,3-beta-glucan synthase [EC:2.4.1.34]
EGGNOG:	0PHH8	FKS1	1,3-beta-glucan synthase
SGD closest match:	S000004334	FKS1	1,3-beta-glucan synthase component FKS1
CGD closest match:	CAL0000176780	GSC1	1,3-beta-glucan synthase

Protein alignments

	%id	Aln length
MIA_01491_1	69.28%	1846	MIA_01491_1
A0A0J9XAT7_GEOCN	60.36%	1796	Similar to Saccharomyces cerevisiae YLR342W FKS1 Catalytic subunit of 1,3-beta-D-glucan synthase OS=Geotrichum candidum GN=BN980_GECA07s03794g PE=4 SV=1
A0A161HFN5_9ASCO	54.61%	1747	1,3-beta-D-glucan synthase OS=Sugiyamaella lignohabitans GN=FKS1 PE=4 SV=1
A0A060TBW8_BLAAD	55.76%	1736	ARAD1D31130p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D31130g PE=4 SV=1
Q6CDD3_YARLI	54.05%	1741	YALI0C01411p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C01411g PE=4 SV=1
UniRef50_Q6CDD3	54.05%	1741	YALI0C01411p n=2 Tax=Yarrowia lipolytica TaxID=4952 RepID=Q6CDD3_YARLI
A0A1E3PP30_9ASCO	54.82%	1731	1,3-beta-glucan synthase component GLS2 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_21892 PE=4 SV=1
A0A1E4TK83_9ASCO	54.30%	1757	Glycosyltransferase family 48 protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_759 PE=4 SV=1
FKS1_YEAST	52.01%	1740	1,3-beta-glucan synthase component FKS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FKS1 PE=1 SV=2
A0A1D8PCT0_CANAL	52.19%	1738	1,3-beta-glucan synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GSC1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1067
Predicted cleavage: 34

Protein family membership

Glycosyl transferase, family 48 (IPR003440)

Domains and repeats

Domain
329 - 441
1,3-beta-glucan synthase subunit FKS1-like, domain-1 (IPR026899)
868 - 1,291
Nucleotide-diphospho-sugar transferases (IPR029044)

1 200 400 600 800 1000 1200 1400 1600 1800 1906

Detailed signature matches

IPR003440

Glycosyl transferase, family 48
1. PF02364 (Glucan_syn...)
  
  840 - 1,678
  
  Pfam
  PF02364 (Glucan_synthase)
IPR026899

1,3-beta-glucan synthase subunit FKS1-like, domain-1
1. SM01205 (FKS1_dom1_2)
  
  329 - 441
  
  SMART
  SM01205 (FKS1_dom1_2)
2. PF14288 (FKS1_dom1)
  
  331 - 438
  
  Pfam
  PF14288 (FKS1_dom1)
IPR029044

Nucleotide-diphospho-sugar transferases
1. G3DSA:3.90.55...
  
  868 - 1,291
  
  GENE3D
  G3DSA:3.90.550.10 (G3DSA:3.90.550.10)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

613 - 704

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1,737 - 1,788

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1,427 - 1,499

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

543 - 562

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1,683 - 1,693

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1,541 - 1,607

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

752 - 1,352

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1,871 - 1,906

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
NON_CYTOPLASM... (N...)

1,633 - 1,658

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

1,519 - 1,523

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

582 - 592

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

1,374 - 1,404

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

1 - 522

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

723 - 727

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

1,813 - 1,849

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

1,713 - 1,717

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

1,523 - 1,540

TMHMM
TMhelix (TMhelix)

591 - 613

TMHMM
TMhelix (TMhelix)

485 - 507

TMHMM
TMhelix (TMhelix)

562 - 584

TMHMM
TMhelix (TMhelix)

707 - 729

TMHMM
TMhelix (TMhelix)

1,723 - 1,745

TMHMM
TMhelix (TMhelix)

1,691 - 1,713

TMHMM
TMhelix (TMhelix)

1,500 - 1,519

TMHMM
TMhelix (TMhelix)

1,611 - 1,633

TMHMM
TMhelix (TMhelix)

650 - 672

TMHMM
TMhelix (TMhelix)

1,409 - 1,426

TMHMM
TMhelix (TMhelix)

1,849 - 1,871

TMHMM
TMhelix (TMhelix)

520 - 542

TMHMM
TMhelix (TMhelix)

1,648 - 1,670

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

1,694 - 1,712

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

705 - 722

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

563 - 581

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,659 - 1,682

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,524 - 1,540

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

523 - 542

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

593 - 612

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,789 - 1,812

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,405 - 1,426

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

728 - 751

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,850 - 1,870

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,718 - 1,736

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,608 - 1,632

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,353 - 1,373

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,500 - 1,518

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
mobidb-lite (disord...)

1,172 - 1,195

MobiDB Lite
mobidb-lite (disorder_prediction)

28 - 92

MobiDB Lite
mobidb-lite (disorder_prediction)

Protein sequence

>MCA_02483_1
MSSYINTSADGSGFQNATASYLNLLTAASRQRSDSSEGGEDDDNTNPDDEDSNSSSEETGSKVDGNNDDDQESNEEDTYS
ISGSEPTSGGETVLSADRMYSALHTGAASLGFQTPFIDPVNIRSAMDSKMGMNPFLSQMPDSESRAAAAAAAAAKGYPLH
ERPEYGTDWNQWSYPAWFDTGGLKGPIPIERIAEMFGDFRAKFGFQRDSMLNIFDHLMTQLDSRASRMGCEMAVISLHAD
YIGGPNSNYKKWYFASQSDILDGIGWDAVDSHGRLNKSFKEKLANPDLEKTVDPNSEKNENEKKNFYMDFSLNSAEIRWK
QIMLRMSHEERLAQVILYLLCWGEANQVRFMPECLCFIYKCSWDYWISDDLQNLEDRKDGVFLDEIITPLYKYCLEQVYE
KTSEGIYAVKERDHNKIIGYDDMNQLFWFREGLLRIKTKDGTCIMDIHRNNRHLELKNVDWEKAFYKTYRENRTWWHMGV
NFNRIWIIHLSTFWFYTAFNSPTLYTEGYDYMVNNQPPAHLKWSIVALGGAVGPLINLYATLGELKFLPRKYPGTRSIYK
KMLFLLLTLFILVSPTCYILLFTSRDNEEKIGLLIAALQMTLAILSTLFFSFQPLAMMFGNYMSGDGNRKYLATKYFAAN
FHPLKSHDRLISIGLWIGIFVAKFTESYFFLTLSLRDPVRELSVVDLQTCIGDKYIGNWLCKRQTYLLLILIYVTDLILF
FLDTYLWYIIFNALFSVFRSFYLGCSIWTPWKDIYSRMLKRIYHKILYTHEKHQGKYKTKHYVSQVWNSIIAGMYSEHLL
PAEAVNALLFRYEFDSKGEKVLYEPHFFVSQEDTASRTVYFEPHTEAERRMSFFAQSLCTPICEPCPIESMPTFTVLIPH
YGEKVMLSLREIIREEDQHSKITLLEYLKQLYPSEWEHFVRDSKGIAKSRTDTSGGHVNGNQTSKSVATILNDEEDSSSA
KLNDLPFYCIGFKQSTPEFTLRTRIWASLRSQTLYRTISGFMNYARAIRLLYNVEQFSNSPNRVNLDQKAVEFELDLQSR
RKFHLIAAVQRLSKFTTEENHSKELLLHAYPEMKIAYLIEEPSSIPGEDPVYYSAIIDGSCKLLQDGSRKPRFKIRLSGN
PILGDGKSDNQNHAIIFYRGEYIQLVDANQDHYLEECIKIRSVLSEFEEMKAPKHPYGTPTGPPKETGARSRSEPRAPVA
IIGAREYIFSENIGVLGDVAAGKEQTFGTLFARTLAKIGGKLHYGHPDFLNGIFMTTRGGVSKAQKGLHLNEDIYAGMNA
VMRGGQIKHCEYMQCGKGRDLGFNSILNFTTKIGAGMGEQMLSREYFYLGTHLPLDRFLSFYYAHPGFHINNMFISISLN
LFLYVCLNLSVLIRESIICDYDRHAPITNLHRPLGCNNLIPVLEWLERCVLSIFVVFFMSFFPLFVQEMTERGIWRSITR
LSRHFASLSPLFEVFVCQIYAQSLVHDLAIGGARYISTGRGFATTRVPFSALYMRFAKQSLYFGAISLLVLTFTSLVMWR
ACLLWFWITSFALTFAPFLYNPHQFSFCEFFLDYREYLKWLCRGNTNWKANSWISYTRKIRTSVIGYKKVTLGDPSEQDS
KGVKRPRFFNVFVSEVIGPLLSMVFTVVPYLFSNAQNDIRGVRATNSLLRLGLCAFGPVAVNAVVLLIQVIMSCSICQLF
VLCSKKSPGKIAGITHFVSLFVHLIFFNVMLFTENWDFSRALLGIIACMNIQLFFFKVLEVLFLTRELPHDHTNRVWWSG
KWFTAKLGWRTLTQPCREFFCKLIECSYFAMDCTLGHFILFIQIPIIIFPYIDRWHTLMLFWLLPSQQIRRPIFSTKQKK
LRKRTVWKYAFLYITVLFLYLVLLIGPFIAHKFIPVDFEKMCNSIIPGIVQPQPPEYTSLGVKHVN

GO term prediction

Biological Process

GO:0006075 (1->3)-beta-D-glucan biosynthetic process

Molecular Function

GO:0003843 1,3-beta-D-glucan synthase activity

Cellular Component

GO:0000148 1,3-beta-D-glucan synthase complex
GO:0016020 membrane

Filter view on

Entry type

Status

Per-residue features