Protein

MCA_02438_1

Length
1,141 amino acids

Description: UvrD-like helicase

Browser: contigB:1308559-1312040+

RNA-seq: read pairs 411, FPKM 4.4, percentile rank 16.6% (100% = highest expression)

Protein function

Annotation:UvrD-like helicase
EGGNOG:0PHACPGUG_02378DNA- helicase
SGD closest match:S000003628SRS2ATP-dependent DNA helicase SRS2
CGD closest match:CAL0000191874orf19.5970DNA helicase

Protein alignments

%idAln lengthE-value
UniRef50_H2AMI341.54%1953e-30Uncharacterized protein n=2 Tax=Kazachstania TaxID=71245 RepID=H2AMI3_KAZAF
MIA_01996_130.72%3191e-32MIA_01996_1
A0A167DCU4_9ASCO28.96%3283e-28DNA helicase SRS2 OS=Sugiyamaella lignohabitans GN=SRS2 PE=4 SV=1
Q5AND3_CANAL27.63%3332e-26DNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5970 PE=4 SV=1
SRS2_YEAST36.59%2053e-26ATP-dependent DNA helicase SRS2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SRS2 PE=1 SV=2
A0A0J9X3H1_GEOCN27.85%4136e-26Similar to Saccharomyces cerevisiae YJL092W SRS2 DNA helicase and DNA-dependent ATPase involved in DNA repair OS=Geotrichum candidum GN=BN980_GECA01s09701g PE=4 SV=1
A0A060TBV0_BLAAD27.22%3382e-21ARAD1B18128p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B18128g PE=4 SV=1
A0A1E3PIX6_9ASCO25.75%3342e-21p-loop containing nucleoside triphosphate hydrolase protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_10623 PE=4 SV=1
Q6C4F2_YARLI42.50%1203e-21YALI0E27269p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E27269g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2922

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 200 400 600 800 1000 1141

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR014016
    UvrD-like helicase, ATP-binding domain
    1. PS51198 (UVRD_HELIC...)
  3. Domain IPR034739
    UvrD/AddA helicase, N-terminal
    1. PF00580 (UvrD-helicase)
  4. Domain IPR014017
    UvrD-like DNA helicase, C-terminal
    1. PS51217 (UVRD_HELIC...)
  5. Domain IPR027785
    UvrD-like helicase C-terminal domain
    1. PF13538 (UvrD_C_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. mobidb-lite (disord...)

Protein sequence

>MCA_02438_1
MSPTVESSTSDSTRQTVKVESINTLIHESTNSIELNNHYQNPQNGTGSIIHTDPNEDFESFLDDDPFSPIDLPSVYDSNN
NNNPTNDNDTQIIDDTHDDGFDDDTHPPYDPNHPLLVDLNYQQQIAVSESPNAILQIIAGPGTGKTKTLSHRVAYLIQHY
RIDPKKIILMTFTKAAAVELSERIAKLLKTCENIDAVKVIKSIQCGTFHSICRKYLVKYSDRIGIKSNFQIINEKRQKEI
IHDILSTRDFHDLTKKFNYIQPNPRVKGWKPDGSLSNEYISPYTILKEIQDAKNQYGLPLEEYLATYDAKSSLMNNIAVL
LRGRRQMEELEVPFSNERIPYHITGGLHFWERKEISTFLKFFKIINSETYPELILDTLEIQKIGFGKKTLEKFSIWTAYS
SELEDSDPNKPKTGRKLSLYEKLEAIVNGNLQPPTTLKSNTMEGLKNYIDLIQSCRDILSLEEYPKSCETVFDKVEKYLS
AVITGLSSDKKQREKRKARIASLKKLVTSIDKYVEEDGYVMDPDTNKKDYLATFLQMAEIGFEDFQTNEDKSSATGDDED
SKNKVTISTIHGAKGLEWPVVFIPRLEHSAAFGSSIPEERRVFYVSITRPSCLCYISMSKIGPGNQPLYMSLPSTDDIVT
YKEMLPLSPEQRLEDDESLMKDLENWEVWDDYEQLEDNVRSTKTNNTNTSNLQVASTDFITCLKDKFPRFLETEAELSCK
FLGKPYVPQNSLTIQDGLHEVSNLKSQITLNNGLFSGFSSARSILKQENVYGNSSSSNSQPSHSPPGLSRKKHAKAEQGK
SSKKSQTGLNLTTSKRTPASAATTKAPNITGHKTIIDLFNSSSSTSRTTVVPSTTSEDTDNDDDGNHNKTQKTKAVTTST
QTATKTHLLLDSSDDDDLFEFNNTLTYTRNAPSASLPSLAKSNSTAITTKVVSSTQISARVLEQPNPSSSSKDLLPLSRP
SSSAVSATPNKSKPTKKQSRKSNKTFEKPSSKDNNNNNSNISSSSKSQPEDDSSLTQKSNNTATPPTPTRPQKKAKRTLT
KSKKSKLPTTATREEEDSPEGRNNNDNNILPTQQTQTQDSSTQNETQTQQSKSQATTTTEITSSAKRKRKSKKPPINNTL
IHSFFQVSSSNSNSNSNKPSA

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005524 ATP binding
GO:0016787 hydrolase activity

Cellular Component

None predicted.