Protein

MCA_02425_1

Length
901 amino acids

Gene name: SRS2

Description: UvrD-like helicase

Browser: contigB:1251040-1253746-

RNA-seq: read pairs 669, FPKM 9.2, percentile rank 24.5% (100% = highest expression)

Protein function

Annotation:SRS2UvrD-like helicase
KEGG:K03657uvrD DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12]
EGGNOG:0PHACPGUG_02378DNA- helicase
SGD closest match:S000003628SRS2ATP-dependent DNA helicase SRS2
CGD closest match:CAL0000191874orf19.5970DNA helicase

Protein alignments

%idAln lengthE-value
A0A167DCU4_9ASCO34.37%7072e-104DNA helicase SRS2 OS=Sugiyamaella lignohabitans GN=SRS2 PE=4 SV=1
UniRef50_A0A167DCU434.37%7074e-101DNA helicase SRS2 n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167DCU4_9ASCO
MIA_01996_131.46%7282e-98MIA_01996_1
A0A060TBV0_BLAAD30.95%6855e-92ARAD1B18128p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B18128g PE=4 SV=1
A0A1E3PIX6_9ASCO31.28%7162e-92p-loop containing nucleoside triphosphate hydrolase protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_10623 PE=4 SV=1
A0A0J9X3H1_GEOCN30.61%7093e-88Similar to Saccharomyces cerevisiae YJL092W SRS2 DNA helicase and DNA-dependent ATPase involved in DNA repair OS=Geotrichum candidum GN=BN980_GECA01s09701g PE=4 SV=1
Q5AND3_CANAL29.99%7272e-76DNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5970 PE=4 SV=1
Q6C4F2_YARLI31.87%7064e-76YALI0E27269p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E27269g PE=4 SV=1
SRS2_YEAST34.19%4655e-68ATP-dependent DNA helicase SRS2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SRS2 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0327

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 700 800 901

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR014016
    UvrD-like helicase, ATP-binding domain
    1. PS51198 (UVRD_HELIC...)
  3. Domain IPR034739
    UvrD/AddA helicase, N-terminal
    1. PF00580 (UvrD-helicase)
  4. Domain IPR014017
    UvrD-like DNA helicase, C-terminal
    1. PF13361 (UvrD_C)
    2. PS51217 (UVRD_HELIC...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. mobidb-lite (disord...)

Protein sequence

>MCA_02425_1
MTKPLQTVETNNNEGSNVTPTYDPKNPILVGLNEEQIIAVTAPSDTIMQILAGPGTGKTKTLAHRTAYLIEHYRVDPSKI
VLMTFTRAAAAELSRRVQKLLKECVGIDYSTSKKLQCGTFHSICRKYLVKYGKNIELSNNFQIINGTRQKNILEEIVTSS
EFKQLVNKFNYTATRGKSWTGYVDGSYQKYTIASILKKIAEIKTNQQMTLTKYLQEYNGKPNFLNGVMSLYNDYVTKRNY
LDFTDLLIYTLELFKKSPHLADEIDHILIDEFQDTDAIQFSMMKLFAGTKPNPITVVGDPDQSIYGFRNAVVENFQYMRD
AYPSIKIVNLIKNYRSSQKLVDMSQEMISLDSSRIDRERKIEAIFDGALQLPTFTDFDDRSLEFSSVASQIKYLVNEYPD
LFSYSDFAILFRAHKHMEGLEPALIHRKIPYYVTGGIQFWERKEISIFLDFFRVISTETYPDAIYETMQIRKFGLGKKKF
QQIVSYEADKSELKDYDPNIDGELQEPMTLLQKIDAISQGRLKPKFPISAGIKGGLRRYMDLINSCIKAFEKYEFPRSGE
IVFNKLQDHLSDYLSELAADESQREARNARVESLKDLVMSTDRFVQEDEYVTDSKTNKINYLATFLQMIEIEDFGLEEER
IFKRGEGEESNKVTISTIHAAKGLEWPVVFIPCLDKCSVWNGEDSEERRVLYVSITRPACLCYISQAKKGTDSGSSNFYS
SYDSGTKYEEMLPWSHKQKNPYIRRYKDKFPKLAKSHAKLFYKLLHRNPNDPSRTKKELAKLYSSSSPSKSSHGTSSSTK
STTPKKRLEHGGGDDDDDTEDERIINATQGGQNKRPKVYVPTSYQLDYSSSDSSLFSSDSENKEKDKTGNGKANSGGGDS
STKTTQTESNKSSKEQDQEPE

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005524 ATP binding
GO:0016787 hydrolase activity

Cellular Component

None predicted.