Protein

MCA_02417_1

Length
616 amino acids

Gene name: NOB1

Description: 20S-pre-rRNA D-site endonuclease NOB1

Browser: contigB:1227878-1229729-

RNA-seq: read pairs 1287, FPKM 25.8, percentile rank 48.4% (100% = highest expression)

Protein function

Annotation:NOB120S-pre-rRNA D-site endonuclease NOB1
KEGG:K11883NOB1 RNA-binding protein NOB1
EGGNOG:0PG29NOB1rna-binding protein
SGD closest match:S000005582NOB120S-pre-rRNA D-site endonuclease NOB1
CGD closest match:CAL0000176350HBR3rRNA-binding endoribonuclease

Protein alignments

%idAln lengthE-value
MIA_01547_158.27%5320.0MIA_01547_1
A0A0J9XK56_GEOCN41.84%2941e-56Similar to Saccharomyces cerevisiae YOR056C NOB1 Protein involved in proteasomal and 40S ribosomal subunit biogenesis OS=Geotrichum candidum GN=BN980_GECA32s00681g PE=4 SV=1
A0A060SX67_BLAAD37.54%2937e-52ARAD1A06864p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A06864g PE=4 SV=1
UniRef50_A0A060SX6737.54%2932e-48ARAD1A06864p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060SX67_BLAAD
A0A161HIM1_9ASCO38.23%2937e-51Nob1p OS=Sugiyamaella lignohabitans GN=NOB1 PE=4 SV=1
Q6C1J1_YARLI37.38%3051e-47YALI0F15829p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F15829g PE=4 SV=1
A0A1E3PQR8_9ASCO36.04%3086e-48D-site 20S pre-rRNA nuclease (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_11304 PE=4 SV=1
NOB1_YEAST32.41%2901e-4120S-pre-rRNA D-site endonuclease NOB1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOB1 PE=1 SV=1
Q59SR4_CANAL31.94%3106e-41rRNA-binding endoribonuclease OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HBR3 PE=4 SV=1
A0A1E4TDC2_9ASCO36.44%2251e-33Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_4385 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3515

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 616

Detailed signature matches

  1. Family IPR017117
    Ribonuclease Nob1, eukaryote
    1. PIRSF037125 (Nob1)
  2. Domain IPR029060
    PIN domain-like
    1. G3DSA:3.40.50...
  3. Domain IPR033411
    Ribonuclease, PIN domain
    1. PF17146 (PIN_6)
  4. Domain IPR014881
    Nin one binding (NOB1) Zn-ribbon-like
    1. SSF144206 (NOB1 zin...)
    2. PF08772 (NOB1_Zn_bind)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. cd09876 (PIN_Nob1)
  3. mobidb-lite (disord...)

Residue annotation

  1. putative active si...

Protein sequence

>MCA_02417_1
MSAPKLSFKDILMKGVEEEQSKPQPDSSKPRAVVVAKAVEPETIKQEDPAAAKKAEEALKKDLSQIEQETRTVQRGPEDP
AIHTLILDAGPLLSQTFSDLQKNAKTFYTTPAVLHTEVRDARARQNIELWQTAGALNVRQPSLHHINAVIDFARKTGDFA
VLSTNDIHILALARELDVEVHGKSEAHLRKAPGSVSAKKQDAMKNANFNSPVTYNVKIEKIRPDQEQDESKKQEEEPKKE
EEGEAKKDDEDDGWAVVTKKNKKKSFNKNQQKNNTQSEEQQKPALTSTMNDMVVTTSYEEEDDESGWITEENIVETMIKD
QYEPDKGSFSSNFNRKPADGDKKEEKKEESAYTTESKKQVEEKFLPVAVSTGDFAMQNVALQMGLNLISPVDGKYVKQVK
NHMLRCHACFHLCPIPKSTDVDEIMYRRQKGAPAPITQEDIASQKKKNFKNTSLSASIIGKGLNFCPKCGAANTLKRCTV
RVSAKDGHIHVYLKRHMQWSTKGNVVQLPVPQSKNSRRAISTTNGRTRDPNSGSAIIVAEDQVEYERAVVHDWKLRKHNE
KVLEEWIGSSDGFDAGLSVSNVSIPFASYNREAARHTGVKIVGGRIGGSGKSRRKK

GO term prediction

Biological Process

GO:0000469 cleavage involved in rRNA processing
GO:0042274 ribosomal small subunit biogenesis

Molecular Function

GO:0004521 endoribonuclease activity

Cellular Component

None predicted.