MCA_02414_1

Protein

Length

1,581 amino acids

Description: ATP-dependent helicase, SNF2 family

RNA-seq: read pairs 465, FPKM 3.6, percentile rank 15.0% (100% = highest expression)

Protein function

Annotation:			ATP-dependent helicase, SNF2 family
EGGNOG:	0QDFW	FG08540.1	SNF2 family helicase ATPase
SGD closest match:	S000005717	ULS1	ATP-dependent helicase ULS1
CGD closest match:	CAL0000187752	orf19.5675	Translocase

Protein alignments

	%id	Aln length	E-value
A0A060T4V2_BLAAD	40.29%	953	0.0	ARAD1B06094p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B06094g PE=4 SV=1
UniRef50_A0A060T4V2	40.29%	953	0.0	ARAD1B06094p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T4V2_BLAAD
MIA_01162_1	41.12%	749	1e-149	MIA_01162_1
A0A0J9X6D8_GEOCN	35.64%	766	8e-126	Similar to Saccharomyces cerevisiae YOR191W ULS1 RING finger protein involved in proteolytic control of sumoylated substrates OS=Geotrichum candidum GN=BN980_GECA03s00549g PE=4 SV=1
A0A1E3PKQ5_9ASCO	41.64%	538	6e-117	Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_12699 PE=4 SV=1
A0A167DVF3_9ASCO	36.90%	496	4e-85	Translocase ULS1 OS=Sugiyamaella lignohabitans GN=ULS1 PE=4 SV=1
A0A1D8PL46_CANAL	32.66%	591	1e-76	Translocase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5675 PE=4 SV=1
Q6BZX0_YARLI	37.93%	435	4e-67	YALI0F30261p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F30261g PE=4 SV=1
ULS1_YEAST	38.64%	264	4e-51	ATP-dependent helicase ULS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ULS1 PE=1 SV=1
A0A1E4THU4_9ASCO	48.07%	181	6e-45	Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_19046 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1134

Protein family membership

None predicted.

Domains and repeats

Domain
657 - 778
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
855 - 967
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
976 - 1,048
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
1,384 - 1,569
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
Domain
662 - 928
Helicase superfamily 1/2, ATP-binding domain (IPR014001)
1,060 - 1,273
Zinc finger, RING/FYVE/PHD-type (IPR013083)
Zinc finger, RING-type (IPR001841)
Domain
679 - 1,044
SNF2-related, N-terminal domain (IPR000330)
1,396 - 1,555
Helicase, C-terminal (IPR001650)

1 200 400 600 800 1000 1200 1400 1581

Detailed signature matches

IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  657 - 778
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  855 - 967
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  976 - 1,048
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,384 - 1,569
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
IPR014001

Helicase superfamily 1/2, ATP-binding domain
1. PS51192 (HELICASE_A...)
  
  678 - 919
  
  PROSITE profiles
  PS51192 (HELICASE_ATP_BIND_1)
2. SM00487 (ultradead3)
  
  662 - 928
  
  SMART
  SM00487 (ultradead3)
IPR000330

SNF2-related, N-terminal domain
1. PF00176 (SNF2_N)
  
  679 - 1,044
  
  Pfam
  PF00176 (SNF2_N)
IPR013083

Zinc finger, RING/FYVE/PHD-type
1. G3DSA:3.30.40.10
  
  1,060 - 1,273
  
  GENE3D
  G3DSA:3.30.40.10 (G3DSA:3.30.40.10)
IPR001841

Zinc finger, RING-type
1. PS50089 (ZF_RING_2)
  
  1,089 - 1,137
  
  PROSITE profiles
  PS50089 (ZF_RING_2)
IPR001650

Helicase, C-terminal
1. PS51194 (HELICASE_CTER)
  
  1,396 - 1,555
  
  PROSITE profiles
  PS51194 (HELICASE_CTER)
2. SM00490 (helicmild6)
  
  1,426 - 1,509
  
  SMART
  SM00490 (helicmild6)
3. PF00271 (Helicase_C)
  
  1,396 - 1,509
  
  Pfam
  PF00271 (Helicase_C)

no IPR

Unintegrated signatures

Coil

29 - 49

COILS
Coil (Coil)
G3DSA:3.40.50...

668 - 968

GENE3D
G3DSA:3.40.50.10810 (G3DSA:3.40.50.10810)
G3DSA:3.40.50...

1,388 - 1,547

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
SSF57850 (RING/U-box)

1,069 - 1,143

SUPERFAMILY
SSF57850 (RING/U-box)
cd00046 (DEXDc)

686 - 788

CDD
cd00046 (DEXDc)
cd00079 (HELICc)

1,388 - 1,516

CDD
cd00079 (HELICc)
cd16513 (RING1-HC_L...)

1,089 - 1,137

CDD
cd16513 (RING1-HC_LONFs)
mobidb-lite (disord...)

783 - 854

MobiDB Lite
mobidb-lite (disorder_prediction)

1,338 - 1,363

MobiDB Lite
mobidb-lite (disorder_prediction)

1,294 - 1,324

MobiDB Lite
mobidb-lite (disorder_prediction)

51 - 107

MobiDB Lite
mobidb-lite (disorder_prediction)

132 - 169

MobiDB Lite
mobidb-lite (disorder_prediction)

198 - 429

MobiDB Lite
mobidb-lite (disorder_prediction)

1,194 - 1,276

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

694G

ATP binding site
694G, 695L, 696G, 697K, 698T
CDD
cd00046 (DEXDc)

695L

ATP binding site
694G, 695L, 696G, 697K, 698T
CDD
cd00046 (DEXDc)

696G

ATP binding site
694G, 695L, 696G, 697K, 698T
CDD
cd00046 (DEXDc)

697K

ATP binding site
694G, 695L, 696G, 697K, 698T
CDD
cd00046 (DEXDc)

698T

ATP binding site
694G, 695L, 696G, 697K, 698T
CDD
cd00046 (DEXDc)
Zn binding site cd...

1,089C

Zn binding site
1,089C, 1,092C, 1,107C, 1,109H, 1,112C, 1,115C, 1,133C, 1,136C
CDD
cd16513 (RING1-HC_LONFs)

1,092C

Zn binding site
1,089C, 1,092C, 1,107C, 1,109H, 1,112C, 1,115C, 1,133C, 1,136C
CDD
cd16513 (RING1-HC_LONFs)

1,107C

Zn binding site
1,089C, 1,092C, 1,107C, 1,109H, 1,112C, 1,115C, 1,133C, 1,136C
CDD
cd16513 (RING1-HC_LONFs)

1,109H

Zn binding site
1,089C, 1,092C, 1,107C, 1,109H, 1,112C, 1,115C, 1,133C, 1,136C
CDD
cd16513 (RING1-HC_LONFs)

1,112C

Zn binding site
1,089C, 1,092C, 1,107C, 1,109H, 1,112C, 1,115C, 1,133C, 1,136C
CDD
cd16513 (RING1-HC_LONFs)

1,115C

Zn binding site
1,089C, 1,092C, 1,107C, 1,109H, 1,112C, 1,115C, 1,133C, 1,136C
CDD
cd16513 (RING1-HC_LONFs)

1,133C

Zn binding site
1,089C, 1,092C, 1,107C, 1,109H, 1,112C, 1,115C, 1,133C, 1,136C
CDD
cd16513 (RING1-HC_LONFs)

1,136C

Zn binding site
1,089C, 1,092C, 1,107C, 1,109H, 1,112C, 1,115C, 1,133C, 1,136C
CDD
cd16513 (RING1-HC_LONFs)
nucleotide binding...

1,418Q

nucleotide binding region
1,418Q, 1,419F, 1,420R, 1,421T, 1,441R, 1,442Y, 1,471L, 1,472K, 1,473A
CDD
cd00079 (HELICc)

1,419F

nucleotide binding region
1,418Q, 1,419F, 1,420R, 1,421T, 1,441R, 1,442Y, 1,471L, 1,472K, 1,473A
CDD
cd00079 (HELICc)

1,420R

nucleotide binding region
1,418Q, 1,419F, 1,420R, 1,421T, 1,441R, 1,442Y, 1,471L, 1,472K, 1,473A
CDD
cd00079 (HELICc)

1,421T

nucleotide binding region
1,418Q, 1,419F, 1,420R, 1,421T, 1,441R, 1,442Y, 1,471L, 1,472K, 1,473A
CDD
cd00079 (HELICc)

1,441R

nucleotide binding region
1,418Q, 1,419F, 1,420R, 1,421T, 1,441R, 1,442Y, 1,471L, 1,472K, 1,473A
CDD
cd00079 (HELICc)

1,442Y

nucleotide binding region
1,418Q, 1,419F, 1,420R, 1,421T, 1,441R, 1,442Y, 1,471L, 1,472K, 1,473A
CDD
cd00079 (HELICc)

1,471L

nucleotide binding region
1,418Q, 1,419F, 1,420R, 1,421T, 1,441R, 1,442Y, 1,471L, 1,472K, 1,473A
CDD
cd00079 (HELICc)

1,472K

nucleotide binding region
1,418Q, 1,419F, 1,420R, 1,421T, 1,441R, 1,442Y, 1,471L, 1,472K, 1,473A
CDD
cd00079 (HELICc)

1,473A

nucleotide binding region
1,418Q, 1,419F, 1,420R, 1,421T, 1,441R, 1,442Y, 1,471L, 1,472K, 1,473A
CDD
cd00079 (HELICc)
ATP-binding site c...

1,479T

ATP-binding site
1,479T, 1,500Q, 1,504R, 1,507R
CDD
cd00079 (HELICc)

1,500Q

ATP-binding site
1,479T, 1,500Q, 1,504R, 1,507R
CDD
cd00079 (HELICc)

1,504R

ATP-binding site
1,479T, 1,500Q, 1,504R, 1,507R
CDD
cd00079 (HELICc)

1,507R

ATP-binding site
1,479T, 1,500Q, 1,504R, 1,507R
CDD
cd00079 (HELICc)

Protein sequence

>MCA_02414_1
MFASMPSREELINRIQSCTPEDPNYNTTISELQKQLQFLDGAAQQTSENNLQNISSSNSSPLISSSSYSSSSPSSSSSRS
NVGTPPTIVHQSPIEKVSNCGPNNQLSNLTMENIQHTQNPPVTMTSSNTNLQAFSNPPATRTFTLANPSLSTPNLSLPPP
NTSSEASAIPNNTSKLFQQPQLQQQGHINNAQLPRVQSLNYLPPPLPVPSNDTRSNPLEIPSQYPNNVNNQLQNQNKPQP
SPGSSKNQPIFSSSFLSNSLPNPFQLNVDKKPDTQQQVKLERKSTSSIPSKVSTPKTIDYIELSDSDDDNEIISSTVTPS
SQPLKSGSSRPPSRSKSLFDMPLFKPFGDINSNSNDPSVAPSPRTNSCTKSLSNLNIGTGLKRPAPESDFIDLTDDSPIP
KKSKENEVSSNPGPPPSLPPPPEKPASVRDFNLDHYSSYFRSKILPDVPNHQKSFAEITENLLKSEITSIRNELSICERE
AVRIYNTMSQIKQTSEAEISRYNSLVTSSRQYIFRIKHLKTDLETFTKEFINFSLKRKPLYNAFLRDAQLLITTKRGDRD
IANRQFMERLSFASKPMLSRSFPSPFTDLNQAKNTIINNMVNMATMSSMKPSKSLFGVKDEVASFVKVKPIDEKDIQNLL
DNVQFDGGDSNPNDRKGTPEGMTITLLEHQKIGLSWLLNKEAKFCGGILADDMGLGKTIQMIALILSRPSSNPEIKTTLI
ITPVALIRQWERELKTRLDKDHQQKVLIYHGLERKNGTFEKMKQYDIVITTYGVIGNEYKEHFPRRSKKNNPNGTRSKYK
RKGSAAASSTPFSEESISGPAPLQSSVMDEEDDDELEEEVENDGEHVTVPGTGRSPFFKDGSVFYRIILDEAQMIKNRKT
RTAISCCRLEASFRWCLSGTPMQNNVSELQSLIKFLRIEPYCDEKKFNTDIGNILDNKSKSKFRSAPNMQGALKKLRVLL
KAIMLRRTKSSKIDGKPLLQLTPREIEINNLAFSPDEQEYYNYLETGAIQTMNKYLVSGSITKNYSNILVMLLRLRQCCC
HPKIIEKANLAKELAAISARSGKAAVAAVRNLNNRVVMSIRTMSDYCTCPCCEENFDKSELVFFSPCGHAICSSCCTSQY
QQSADDADNRTRCVVCNHVFDQKGFFDYIVFKWVHILKLNDSQIASQRFLANRTTRANRLNAINEMIAKEGARKPIIDDD
DDDLFGEKDTTPQSSKTDTTSTDVKNVKTEEKVNLPVPDEVDDTQIDSDDSVQEIKPEDIGLPASSTATDSSTQVDSKNP
FIIDEEGDDLFGTKPSLNGSTTVKNEGTSGNNLVKNEEQSGSTTVKDEIGVKDETLVKGEDSPDGISVPTLDSKNVYSST
TTEESGKDITFGARVTRPDLMPIFPNGWISSTKVDQCMRLIEKIRADYPGEKILVFSQFRTMLDFIEVAFEVRNSEVEYC
RYDGSMNATRRHETVVSFTDNPRISVLLISLKAGNVGLTLTAASHVILIDPFWNPFVEEQAMDRAHRIGQTRTVHIHRLY
IQSSVEDRILRLQEKKRLLIGAALDEKELKTLSSLNQTELLYLFGMDSRGHRSANLEVPDS

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005524 ATP binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MCA_02414_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component