Protein

MCA_02402_1

Length
467 amino acids

Browser: contigB:1174397-1175960-

RNA-seq: read pairs 1405, FPKM 37.1, percentile rank 58.7% (100% = highest expression)

Protein function

KEGG:K01487E3.5.4.3 guanine deaminase [EC:3.5.4.3]
EGGNOG:0PG2GPGUG_00164Guanine deaminase
SGD closest match:S000002397GUD1Probable guanine deaminase
CGD closest match:CAL0000177418orf19.7029Guanine deaminase

Protein alignments

%idAln lengthE-value
A0A0J9X9D5_GEOCN69.11%4630.0Similar to Saccharomyces cerevisiae YDL238C GUD1 Guanine deaminase, a catabolic enzyme of the guanine salvage pathway producing xanthine and ammonia from guanine OS=Geotrichum candidum GN=BN980_GECA06s00780g PE=4 SV=1
MIA_01686_164.66%4640.0MIA_01686_1
S6EAV4_BLAAD56.21%4752e-177Guanine deaminase (Fragment) OS=Blastobotrys adeninivorans GN=AGDA PE=4 SV=1
UniRef50_A0A1E3Q5G455.77%4594e-169Uncharacterized protein n=50 Tax=saccharomyceta TaxID=716545 RepID=A0A1E3Q5G4_LIPST
Q6C4L7_YARLI56.16%4639e-170YALI0E25740p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E25740g PE=4 SV=1
GUAD_YEAST46.64%4762e-135Probable guanine deaminase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GUD1 PE=1 SV=1
A0A170QZU5_9ASCO61.03%2905e-130Guanine deaminase OS=Sugiyamaella lignohabitans GN=GUD1 PE=4 SV=1
A0A1E3PT60_9ASCO56.60%3416e-124Metallo-dependent hydrolase (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45114 PE=4 SV=1
A0A1D8PQQ8_CANAL39.56%5467e-114Guanine deaminase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7029 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1076

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 467

Detailed signature matches

  1. Family IPR014311
    Guanine deaminase
    1. TIGR02967
  2. Domain IPR032466
    Metal-dependent hydrolase
    1. SSF51556 (Metallo-d...)
  3. Domain IPR006680
    Amidohydrolase-related
    1. PF01979 (Amidohydro_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.20.20...

Protein sequence

>MCA_02402_1
MTSTKSLTAYFGTFVHPQNLQKLEILLKATIGVDNKTGEIVFVDKDSKSPEEALSKAGVDPKSAKVVTSTSSKAAFFFPG
MFDTHIHASQYPNSGIFGKSTLLDWLTTYTFPLESSFKDIEKAKTIYSKVIDRTISNGTTTAAYYATIHTEATKLLADIA
LERGQRAFVGRVCMNQNSPDFYKDESEEQSKERDLEVIDYIKKIDPTYEIISPIFTPRFAPSCTHSSMKWMGDMMKKTGL
PCQTHISENANEIAWVKELFPQCKNYTDVYDTAGVLGDRTILAHAIHLTQEELDVIKARKSGISHCPISNSSITSGEAPI
RKYMDQGIKVSLGTDVSGGFAASVLETARQTLLVSRHVSMKSSSENDKLSVDEVLCLATLGGAQVCGLQDKLGNFEVGKK
WDALLIDLECQDSPVDVFEWQEIKQQDGDSDKAIERMENLIAKWLFGGDNRNVANVWVNGQLVKGTL

GO term prediction

Biological Process

GO:0006147 guanine catabolic process

Molecular Function

GO:0008270 zinc ion binding
GO:0008892 guanine deaminase activity
GO:0016787 hydrolase activity

Cellular Component

None predicted.