Protein

MCA_02349_1

Length
626 amino acids

Gene name: LCB2

Description: Serine palmitoyltransferase 2

Browser: contigB:1028609-1030490+

RNA-seq: read pairs 5217, FPKM 102.8, percentile rank 79.2% (100% = highest expression)

Protein function

Annotation:LCB2Serine palmitoyltransferase 2
KEGG:K00654SPT serine palmitoyltransferase [EC:2.3.1.50]
EGGNOG:0PG3ULCB2serine palmitoyltransferase
SGD closest match:S000002469LCB2Serine palmitoyltransferase 2
CGD closest match:CAL0000186740LCB2Serine C-palmitoyltransferase

Protein alignments

%idAln lengthE-value
MIA_01117_178.14%5490.0MIA_01117_1
A0A0J9X2G2_GEOCN70.63%5380.0Similar to Saccharomyces cerevisiae YDR062W LCB2 Component of serine palmitoyltransferase OS=Geotrichum candidum GN=BN980_GECA01s01407g PE=4 SV=1
A0A1E3PEQ2_9ASCO66.97%5420.0PLP-dependent transferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48232 PE=4 SV=1
A0A161HMC6_9ASCO66.43%5540.0Serine C-palmitoyltransferase LCB2 OS=Sugiyamaella lignohabitans GN=LCB2 PE=4 SV=1
A0A060SZ14_BLAAD62.71%5470.0ARAD1C05060p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C05060g PE=4 SV=1
Q6C1K9_YARLI60.48%5390.0YALI0F15345p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F15345g PE=4 SV=1
UniRef50_E9R3D157.45%5640.0Serine palmitoyltransferase 2, putative n=221 Tax=Fungi TaxID=4751 RepID=E9R3D1_ASPFU
LCB2_YEAST58.08%5320.0Serine palmitoyltransferase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LCB2 PE=1 SV=1
Q5AKV0_CANAL57.06%5380.0Serine C-palmitoyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LCB2 PE=4 SV=1
A0A1E4TGF4_9ASCO55.99%5430.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_112307 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0277

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 626

Detailed signature matches

  1. Domain IPR015421
    Pyridoxal phosphate-dependent transferase, major region, subdomain 1
    1. G3DSA:3.40.64...
  2. Domain IPR015424
    Pyridoxal phosphate-dependent transferase
    1. SSF53383 (PLP-depen...)
  3. Domain IPR004839
    Aminotransferase, class I/classII
    1. PF00155 (Aminotran_1_2)
  4. Domain IPR015422
    Pyridoxal phosphate-dependent transferase, subdomain 2
    1. G3DSA:3.90.11...
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)
  5. cd06454 (KBL_like)
  6. mobidb-lite (disord...)

Residue annotation

  1. substrate-cofactor...
  2. pyridoxal 5'-phosp...
  3. catalytic residue ...

Protein sequence

>MCA_02349_1
MTTELESPKIIESPAMKAAKFAEQALASEYPEIEQDLQRELHHHHPHNDEHIIPSIHDSSLPSHKKQQHHHTTKEPTQLS
SVGAKSSHLHESEFGELTSTKYLYKSNWPAGKSLPKEEEDLPSLYVFVTTYLSYLVLIIMGHVEDFFARIFRSEEHKYLQ
VSNGFAPFVDEFESFYVRRQKHRLNDCFGRVTTGVPGRYITVLDRTSDDFYTTFKYPGTTTNCLNLSSYNYLGFAQSAGQ
CTDTAEIAIRTYGPTSGAPRLAGGATDYHVISEKVVADFLGKESSLIYSMGYGTNATIFSALIDKNCLVISDELNHASIR
FGVRMSGAVIRIFKHNDMEDLERVLREQISQGQPRTHRPWKKILIIVEGLYSMEGTMCNLPELVRLRKKYKFYLFVDEAH
SVGAIGPRGRGVADFFSIDPSEIDIMMGTLTKSFGATGGYIAANKDIIDKIKVTNLANIYAESPAPPVLAQINSSLLTIT
GDVNNGEGQERLQRIAFNSRYLRLGLKKLGFIVSGMDDSPIIPVMLYHPTKMPAFSRLMLEKKIAVVVVGYPATPLTSSR
VRLCVSASLTKEDLDYLLREMDIAGDELHFKMSCELSPKTGKLRRENVEDVLKTLVDDVQQDLSQF

GO term prediction

Biological Process

GO:0009058 biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0030170 pyridoxal phosphate binding

Cellular Component

None predicted.