Protein

MCA_02314_1

Length
507 amino acids

Gene name: CBF5

Description: H/ACA ribonucleoprotein complex subunit 4

Browser: contigB:917499-919023+

RNA-seq: read pairs 5401, FPKM 131.4, percentile rank 83.1% (100% = highest expression)

Protein function

Annotation:CBF5H/ACA ribonucleoprotein complex subunit 4
KEGG:K11131DKC1 H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
EGGNOG:0PFV3CBF5centromere microtubule-binding protein CBF5
SGD closest match:S000004165CBF5H/ACA ribonucleoprotein complex subunit 4
CGD closest match:CAL0000194674CBF5Centromere/microtubule-binding protein CBF5

Protein alignments

%idAln lengthE-value
MIA_00843_194.86%3890.0MIA_00843_1
A0A0J9XLA7_GEOCN88.72%3900.0Similar to Saccharomyces cerevisiae YLR175W CBF5 Pseudouridine synthase catalytic subunit of box H/ACA small nucleolar ribonucleoprotein particles (SnoRNPs) OS=Geotrichum candidum GN=BN980_GECA32s01022g PE=4 SV=1
A0A161HNA9_9ASCO81.96%4380.0Pseudouridine synthase CBF5 OS=Sugiyamaella lignohabitans GN=CBF5 PE=4 SV=1
A0A1E3PLY6_9ASCO86.67%3900.0Putative rRNA pseudouridine synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50365 PE=4 SV=1
Q6C609_YARLI86.92%3900.0YALI0E13486p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E13486g PE=4 SV=1
A0A060T2P2_BLAAD86.58%3950.0ARAD1C34188p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C34188g PE=4 SV=1
CBF5_YEAST86.89%3890.0H/ACA ribonucleoprotein complex subunit 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CBF5 PE=1 SV=1
UniRef50_P3332286.89%3890.0H/ACA ribonucleoprotein complex subunit 4 n=704 Tax=Eukaryota TaxID=2759 RepID=CBF5_YEAST
CBF5_CANAL84.42%3850.0Centromere/microtubule-binding protein CBF5 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CBF5 PE=3 SV=1
A0A1E4TF75_9ASCO78.01%3910.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_106344 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1059

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 350 400 450 507

Detailed signature matches

  1. Family IPR004802
    tRNA pseudouridine synthase B family
    1. TIGR00425
  2. Domain IPR012960
    Dyskerin-like
    1. PF08068 (DKCLD)
    2. SM01136 (DKCLD_2)
  3. Domain IPR020103
    Pseudouridine synthase, catalytic domain
    1. SSF55120 (Pseudouri...)
  4. Domain IPR002501
    Pseudouridine synthase II, N-terminal
    1. PF01509 (TruB_N)
  5. Domain IPR032819
    tRNA pseudouridylate synthase B, C-terminal
    1. PF16198 (TruB_C_2)
  6. Domain IPR015947
    PUA-like domain
    1. SSF88697 (PUA domai...)
  7. Domain IPR002478
    PUA domain
    1. G3DSA:2.30.13...
    2. PF01472 (PUA)
    3. PS50890 (PUA)
    4. SM00359 (pua_5)
  8. Domain IPR004521
    Uncharacterised domain CHP00451
    1. TIGR00451
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.30.23...
  3. cd02572 (PseudoU_sy...)
  4. mobidb-lite (disord...)

Residue annotation

  1. probable active si...

Protein sequence

>MCA_02314_1
MSKEIEEFQIKPTNTTAKVDTSEWPLLLKNYEKLLVRSGHYTPIPVGCSPLKRDLKSYIQSGVINLDKPSNPSSHEVVAW
IKRILRVEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCIVRLHDALKDEKDMGRALEQLTGALFQRPPLIS
AVKRQLRVRTIYDSKLYEFDNDRHLGVFWASCEAGTYMRTLCVHLGMLLGVGGHMQELRRVRSGALSENDEMVTLHDILD
AQWLYDNTKDESYLRSCIKPLETLLLGYKRVVVKDSAVNSVCYGAKLMIPGLLRYEAGIEMDDEVVLITTKGEAIAIGIA
QMSTVDLSTCDHGVVAKIKRCIMERDTYPRRWGLGPVAQRKKQLKTDGKLDKFGRPNENTPESWKKEYVDHTAPDSENPS
AATASSSSSVPATPAKPATPLVKDITETPATASKTDNDESDDSMGEATPSKAKKEKKEKKDKKEKKEKKEKKDKKEKKEK
KEKKRKADDDSDDEDKSEKKKKKSKKD

GO term prediction

Biological Process

GO:0001522 pseudouridine synthesis
GO:0006396 RNA processing
GO:0009451 RNA modification

Molecular Function

GO:0003723 RNA binding
GO:0009982 pseudouridine synthase activity

Cellular Component

None predicted.