Protein

MCA_02304_1

Length
657 amino acids

Gene name: KIC1B

Description: Putative protein kinase with some homology to S. cerevisiae Kic1

Browser: contigB:888414-890874-

RNA-seq: read pairs 1593, FPKM 29.9, percentile rank 52.6% (100% = highest expression)

Protein function

Annotation:KIC1BPutative protein kinase with some homology to S. cerevisiae Kic1
KEGG:K08838STK24_25_MST4 serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
EGGNOG:0PF80PGUG_02630serine threonine protein kinase
SGD closest match:S000001144KIC1Serine/threonine-protein kinase KIC1
CGD closest match:CAL0000180548orf19.3456Uncharacterized protein

Protein alignments

%idAln lengthE-value
MIA_01145_169.67%3334e-162MIA_01145_1
A0A060T5M0_BLAAD68.12%3202e-148ARAD1B07920p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B07920g PE=4 SV=1
A0A0J9X8M8_GEOCN70.16%3151e-143Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA04s04608g PE=4 SV=1
UniRef50_A0A0J9X8M870.16%3152e-140Uncharacterized protein n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X8M8_GEOCN
Q6C8H9_YARLI64.67%3179e-141YALI0D19470p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D19470g PE=4 SV=1
A0A1E4TA33_9ASCO57.83%3133e-128Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_45110 PE=4 SV=1
A0A1E3PJN6_9ASCO57.42%3572e-118Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50843 PE=4 SV=1
A0A167DXM4_9ASCO61.46%3018e-115Putative serine/threonine protein kinase KIC1 OS=Sugiyamaella lignohabitans GN=KIC1 PE=4 SV=1
A0A1D8PPU9_CANAL52.55%2748e-88Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3456 PE=4 SV=1
KIC1_YEAST48.45%2585e-78Serine/threonine-protein kinase KIC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KIC1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2953
Predicted cleavage: 15

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 657

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.51...
  3. G3DSA:3.30.20...
  4. PIRSF000615 (TyrPK_...)
  5. cd06609 (STKc_MST3_...)
  6. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd06609
  3. polypeptide substr...
  4. activation loop (A...

Protein sequence

>MCA_02304_1
MTGNRLFSSDQFTLTEELGRGSFGVVYKGIDKITNQVVAVKQIDMETSEEDIEEIQKEIAILAGCHDSHITRYYGCFVKG
HKLWIIMEYLGGGSALDLLKPGPFDEHSIAIICRELLLGLEYLHENGKIHRDVKAANVLMSDQGHVKIGDFGVATQLTNN
LSKRNTFVGTPFWMAPEVILQNDYDHKADIWSLGITAIEFAKGEPPLCRNHPMRVLFDIPKNDPPQLDGDEFSKTFKDFV
SECLRKDPRERASVKTLLKHKFIKNSGKTSDLISMIQNRQAKLKLRAKKKPNYQSTIESEGFNTSNNGYDTGWDFDTVKS
SSYISSSPTPNQQKFPQQQQPNVLTDVSNILPSNYKPLDNRKDQPEPASPTSSQNSTIKKRPSVNQRSLRHSNNNSSSTT
TSNNNMHSHPHSHASATPSNNKMGLSSPSSSPAHAASRRHRPSASSSLSISASSSINRQQPDDYHYKAERGRVVQRGVES
AISRVQENSDLAKSFSRILQVLVEEASVLTVQQELYLAKKIVENIQKDDMVKDLIFPATTEGINSSTVNNTRRQVKHGGG
ASVSTTDPRQYSVSTSSTTGTAIHHHHNHPSNKTNWSVGTEQIRNTQLDQMLYAHSTANTNNDLLSSGPNAIRSDMDPVE
ELLLNRWIEGFNERWGN

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.