Protein

MCA_02268_1

Length
541 amino acids

Gene name: APE3

Description: Aminopeptidase Y

Browser: contigB:761706-763332-

RNA-seq: read pairs 8461, FPKM 192.9, percentile rank 87.7% (100% = highest expression)

Protein function

Annotation:APE3Aminopeptidase Y
KEGG:K01264APE3 aminopeptidase Y [EC:3.4.11.15]
EGGNOG:0PFQKPGUG_03742aminopeptidase Y
SGD closest match:S000000490APE3Aminopeptidase Y
CGD closest match:CAL0000192750APE3Peptide hydrolase

Protein alignments

%idAln lengthE-value
MIA_03855_166.48%5430.0MIA_03855_1
A0A0J9XHY5_GEOCN64.42%4890.0Peptide hydrolase OS=Geotrichum candidum GN=BN980_GECA19s01044g PE=3 SV=1
UniRef50_A0A0J9XIL460.89%5420.0Peptide hydrolase n=2 Tax=saccharomyceta TaxID=716545 RepID=A0A0J9XIL4_GEOCN
A0A1E3PR37_9ASCO56.81%4779e-173Peptide hydrolase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_44503 PE=3 SV=1
Q6CDU2_YARLI58.35%4492e-172Peptide hydrolase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B21186g PE=3 SV=1
A0A060T5U7_BLAAD54.07%4797e-167Peptide hydrolase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B14608g PE=3 SV=1
A0A167FX70_9ASCO58.00%4504e-159Peptide hydrolase OS=Sugiyamaella lignohabitans GN=APE3 PE=3 SV=1
A0A1D8PI95_CANAL52.40%4795e-154Peptide hydrolase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=APE3 PE=3 SV=1
APE3_YEAST50.22%4584e-142Aminopeptidase Y OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APE3 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0971

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 500 541

Detailed signature matches

  1. Domain IPR003137
    PA domain
    1. PF02225 (PA)
  2. Domain IPR007484
    Peptidase M28
    1. PF04389 (Peptidase_M28)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.63...
  2. NON_CYTOPLASM... (N...)
  3. PS51257 (PROKAR_LIP...)
  4. SIGNAL_PEPTIDE (Sig...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. SSF52025 (PA domain)
  9. SSF53187 (Zn-depend...)
  10. SignalP-noTM
  11. cd02130 (PA_ScAPY_like)
  12. cd03876 (M28_SGAP_like)

Residue annotation

  1. PA/protease or pro...
  2. active site cd03876
  3. metal binding site...

Protein sequence

>MCA_02268_1
MKFSTILVAASAASCSTALPLGSSESWYSWAIEKAQQITFGLPYESIEEVQPTPETAGPWPPITKPLVSSEALQALINEP
ALHIQVGKLYKAALIGAGMYGHPTRVIGSAGHFMTLSNIEKTLYSLGPYYNVTKQYFNATRGVIFKSSLSVEDVIITATP
FDLTPPTPKKKPVTAPLVLVSNNGCNTSDFPASANGSIVLIERGVCAFGDKSENAGLAGAVAAIIYNNVPGEATFGGTLG
TPLPEQVATLGVTYEVGSEWASQLAQNISLNATAMVDSFVKNVTTYNIIADTRTGDENNVVMLGAHSDSVTAGPGINDDG
SGTISLLEVATALSKFSVTNKVRFAWWAAEEEGLIGSDYYVSQLLPEENAKIRLFMDYDMMASPNYAFQVYDANNSANPE
GSEELKQLYIDYYTSQGVNHTLIPFDGRSDYDAFIKNGIPGGGVAAGAEVLKTPEEVEMFGGVAGVPYDKCYHQLCDDPF
NLNYYAFMMNTKLIAHAVGTYAASLDGFPVRKPVTPVSAAASSVAPKRAQEYKFHGPKVVL

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.