Protein

MCA_02233_1

Length
366 amino acids

Browser: contigB:667458-668559+

RNA-seq: read pairs 14305, FPKM 481.6, percentile rank 94.1% (100% = highest expression)

Protein function

KEGG:K05757ARPC1A_B actin related protein 2/3 complex, subunit 1A/1B
EGGNOG:0PIRYFG00610.13 complex
SGD closest match:S000000438ARC40Actin-related protein 2/3 complex subunit 1
CGD closest match:CAL0000175984ARC40Arc40p

Protein alignments

%idAln lengthE-value
MIA_03954_182.51%3660.0MIA_03954_1
A0A0J9XCG8_GEOCN73.83%3630.0Similar to Saccharomyces cerevisiae YBR234C ARC40 Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches OS=Geotrichum candidum GN=BN980_GECA08s00736g PE=4 SV=1
A0A167FG33_9ASCO72.58%3610.0Arc40p OS=Sugiyamaella lignohabitans GN=ARC40 PE=4 SV=1
UniRef50_A0A167FG3372.58%3610.0Arc40p n=324 Tax=Eukaryota TaxID=2759 RepID=A0A167FG33_9ASCO
A0A060TIR8_BLAAD67.03%3670.0ARAD1D40238p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D40238g PE=4 SV=1
A0A1E3PF98_9ASCO65.57%3660.0ARP2/3 actin-organizing complex subunit Sop2 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53041 PE=4 SV=1
A0A1E4TFP6_9ASCO63.41%3585e-176Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_107199 PE=4 SV=1
Q6CE98_YARLI59.31%3764e-163YALI0B17380p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B17380g PE=4 SV=1
A0A1D8PT60_CANAL51.70%3834e-141Arc40p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ARC40 PE=4 SV=1
ARPC1_YEAST44.88%3812e-108Actin-related protein 2/3 complex subunit 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARC40 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0168

Protein family membership

Domains and repeats

  1. Domain
  2. Repeat
1 50 100 150 200 250 300 366

Detailed signature matches

  1. Family IPR017383
    Actin-related protein 2/3 complex subunit 1
    1. PIRSF038093 (ARPC1)
  2. Domain IPR015943
    WD40/YVTN repeat-like-containing domain
    1. G3DSA:2.130.1...
  3. Domain IPR017986
    WD40-repeat-containing domain
    1. SSF50978 (WD40 repe...)
    2. PS50294 (WD_REPEATS...)
  4. Repeat IPR001680
    WD40 repeat
    1. PF00400 (WD40)
    2. PS50082 (WD_REPEATS_2)
    3. SM00320 (WD40_4)
  5. SITE IPR019775
    WD40 repeat, conserved site
    1. PS00678 (WD_REPEATS_1)

Protein sequence

>MCA_02233_1
MAPHKSFSLGHTPISDHAFSDDHSLLALARDTNVELYYSDGKHFELGNTLTDHDKTVTSVDISASGRLVTCSQDRNALVW
EIQADGSWKPTLVLLRINRAATFVRWSPDEKKFAVGSGARVVAVCYFEEENDWWISKHIKKPIRSTILSVAWHPNSVLLA
AGSTDGHARVFSSFIKSVDARPAPTNWGERIPFQTLCGDFVSESGGWVHDVSFSPSGDALGFVTHDSSVVIAYPGGPEQP
PRAVVSVSTSMLPLKSLVWANENSIIAAGYDCHPIVFQGDESGWKFTSSIDDPSKAARSEAKENTALNMFRQLDLKGTVD
NDSGSTSLPTIHQNAITRIRAYESNSSGVSKISSTGNDGKVVIYQL

GO term prediction

Biological Process

GO:0030833 regulation of actin filament polymerization
GO:0034314 Arp2/3 complex-mediated actin nucleation

Molecular Function

GO:0005515 protein binding

Cellular Component

GO:0005885 Arp2/3 protein complex
GO:0015629 actin cytoskeleton