Protein

MCA_02229_1

Length
310 amino acids

Gene name: SIT4

Description: Serine/threonine-protein phosphatase PP1-1

Browser: contigB:661113-662117+

RNA-seq: read pairs 2649, FPKM 105.2, percentile rank 79.6% (100% = highest expression)

Protein function

Annotation:SIT4Serine/threonine-protein phosphatase PP1-1
KEGG:K15427SIT4 serine/threonine-protein phosphatase PP1-1 [EC:3.1.3.16]
EGGNOG:0PGS9PGUG_01122serine threonine-protein phosphatase
SGD closest match:S000002205SIT4Serine/threonine-protein phosphatase PP1-1
CGD closest match:CAL0000187173SIT4Serine/threonine-protein phosphatase SIT4

Protein alignments

%idAln lengthE-value
MIA_03959_191.77%3160.0MIA_03959_1
A0A060TCJ1_BLAAD88.03%3090.0Serine/threonine-protein phosphatase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D39578g PE=3 SV=1
A0A1E3PLP1_9ASCO87.30%3070.0Serine/threonine-protein phosphatase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_23482 PE=3 SV=1
A0A0J9YHM5_GEOCN89.29%3080.0Serine/threonine-protein phosphatase OS=Geotrichum candidum GN=BN980_GECA01s06665g PE=3 SV=1
PP11_YEAST85.06%3080.0Serine/threonine-protein phosphatase PP1-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SIT4 PE=1 SV=1
UniRef50_P2060485.06%3080.0Serine/threonine-protein phosphatase PP1-1 n=164 Tax=Eukaryota TaxID=2759 RepID=PP11_YEAST
SIT4_CANAL83.01%3120.0Serine/threonine-protein phosphatase SIT4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SIT4 PE=1 SV=1
A0A161HLZ1_9ASCO89.78%2740.0Serine/threonine-protein phosphatase OS=Sugiyamaella lignohabitans GN=SIT4 PE=3 SV=1
A0A1E4TAH1_9ASCO80.07%2910.0Serine/threonine-protein phosphatase (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11928 PE=3 SV=1
Q6C264_YARLI55.06%3161e-130Serine/threonine-protein phosphatase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F10505g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0281

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 310

Detailed signature matches

  1. Domain IPR029052
    Metallo-dependent phosphatase-like
    1. SSF56300 (Metallo-d...)
    2. G3DSA:3.60.21.10
  2. Domain IPR004843
    Calcineurin-like phosphoesterase domain, ApaH type
    1. PF00149 (Metallophos)
  3. Domain IPR006186
    Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
    1. PS00125 (SER_THR_PH...)
    2. SM00156 (pp2a_7)
    3. PR00114 (STPHPHTASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd07415 (MPP_PP2A_P...)

Residue annotation

  1. heterotrimer inter...
  2. metal binding site...
  3. active site cd07415

Protein sequence

>MCA_02229_1
MSTERGPDVWLEEVRKCQYLPENDMKHLCEMVKELLMEESNIQPVQSPVTVCGDIHGQFHDLLELFRVAGGMPDDVNYVF
LGDFVDRGYFSLETFTLLMCLKVKYPQRLTLVRGNHESRQITQVYGFYEECLNKYGSSTVWKYCCQVFDFLTLAAIIDGK
ILCVHGGLSPEIRMLDQIRVLSRAQEIPHEGGFCDLVWSDPDELETWAVSPRGAGWLFGSKVAREFNHLNNLSLIARAHQ
LVMEGFKYHFQEKDVVTVWSAPNYCYRCGNVASVMKVEEDLAPEFTIFNAVPDDTLQMAPQKNQRSEYFL

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016787 hydrolase activity

Cellular Component

None predicted.