Protein

MCA_02202_1

Length
185 amino acids

Browser: contigB:579519-580766+

RNA-seq: read pairs 2041, FPKM 135.6, percentile rank 83.6% (100% = highest expression)

Protein function

KEGG:K07941ARF6 ADP-ribosylation factor 6
EGGNOG:0PGCDFG04483.1adp-ribosylation factor
SGD closest match:S000005620ARF3ADP-ribosylation factor 3
CGD closest match:CAL0000178804ARF2Arf family GTPase

Protein alignments

%idAln lengthE-value
A0A0J9X3G0_GEOCN96.15%1821e-129Similar to Saccharomyces cerevisiae YOR094W ARF3 Glucose-repressible ADP-ribosylation factor, GTPase of the Ras superfamily involved in development of polarity OS=Geotrichum candidum GN=BN980_GECA01s09448g PE=3 SV=1
A0A060T0J1_BLAAD93.41%1821e-126ARAD1C08448p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C08448g PE=3 SV=1
Q6CBX8_YARLI90.45%1789e-121YALI0C14586p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C14586g PE=3 SV=2
A0A1E3PCP9_9ASCO87.15%1794e-118ARF/SAR superfamily OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53461 PE=3 SV=1
MIA_04006_193.79%1612e-112MIA_04006_1
UniRef50_P6233073.26%1725e-92ADP-ribosylation factor 6 n=49 Tax=Opisthokonta TaxID=33154 RepID=ARF6_HUMAN
A0A167DBV5_9ASCO67.23%1778e-87Arf family GTPase ARF2 OS=Sugiyamaella lignohabitans GN=ARF2 PE=3 SV=1
Q5AND9_CANAL65.54%1771e-85Arf family GTPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ARF2 PE=1 SV=1
ARF3_YEAST62.64%1822e-85ADP-ribosylation factor 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARF3 PE=1 SV=2
A0A1E4TKS6_9ASCO64.97%1776e-85Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22453 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5374

Protein family membership

Domains and repeats

  1. Domain
1 20 40 60 80 100 120 140 160 185

Detailed signature matches

  1. Family IPR006689
    Small GTPase superfamily, ARF/SAR type
    1. PF00025 (Arf)
    2. PR00328 (SAR1GTPBP)
  2. Family IPR024156
    Small GTPase superfamily, ARF type
    1. PS51417 (ARF)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR005225
    Small GTP-binding protein domain
    1. TIGR00231
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. SM00175 (rab_sub_5)
  3. SM00177 (arf_sub_2)
  4. SM00178 (sar_sub_1)
  5. cd04149 (Arf6)

Residue annotation

  1. G1 box cd04149
  2. putative GAP inter...
  3. GTP/Mg2+ binding s...
  4. Switch I region cd...
  5. QS Arf6 conserved ...
  6. G2 box cd04149
  7. putative GEF inter...
  8. putative effector ...
  9. interswitch region...
  10. G3 box cd04149
  11. Switch II region c...
  12. G4 box cd04149
  13. G5 box cd04149

Protein sequence

>MCA_02202_1
MGLSMSKILSKLFGSREIRILMLGLDAAGKTTILYKLKLNQGISTVPTVGFNVETLTYKNIRFNVWDVGGQEKIRPLWRH
YFTGTQGLIFVVDSADRARIDEARQELHRIISDREMKDALLLVFANKQDLQDAMHPKEITERLQLDTLKGRTWCVVASTA
KTGEGLVEGLSWLSTNIPEDRKMKN

GO term prediction

Biological Process

GO:0007264 small GTPase mediated signal transduction

Molecular Function

GO:0005525 GTP binding

Cellular Component

GO:0005622 intracellular