Protein
MCA_02188_1
Length
1,965 amino acids
Description: ATP-binding cassette, subfamily B (MDR/TAP), member 1
Browser: contigB:510461-516798+
RNA-seq: read pairs 94, FPKM 0.6, percentile rank 7.4% (100% = highest expression)
Protein function
| Annotation: | ATP-binding cassette, subfamily B (MDR/TAP), member 1 | ||
|---|---|---|---|
| KEGG: | K05658 | ABCB1 | ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:3.6.3.44] |
| EGGNOG: | 0PGKJ | MDR1 | Multidrug resistance protein |
| SGD closest match: | S000006191 | MDL2 | ATP-dependent permease MDL2, mitochondrial |
| CGD closest match: | CAL0000176022 | MDL2 | Mdl2p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03994_1 | 50.82% | 728 | 0.0 | MIA_03994_1 |
| A0A060SYY2_BLAAD | 38.05% | 636 | 2e-129 | ARAD1A15114p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A15114g PE=4 SV=1 |
| A0A0J9XFY3_GEOCN | 36.13% | 631 | 3e-126 | Similar to Saccharomyces cerevisiae YKL209C STE6 Plasma membrane ATP-binding cassette (ABC) transporter required for the export of a-factor OS=Geotrichum candidum GN=BN980_GECA12s02551g PE=4 SV=1 |
| A0A1E3PRN7_9ASCO | 35.93% | 643 | 2e-125 | p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48738 PE=4 SV=1 |
| A0A167CY34_9ASCO | 35.38% | 636 | 6e-124 | ATP-binding cassette alpha-factor transporter STE6 OS=Sugiyamaella lignohabitans GN=STE6 PE=4 SV=1 |
| UniRef50_A0A161HLQ6 | 35.44% | 632 | 2e-117 | ATP-binding cassette alpha-factor transporter STE6 n=13 Tax=Saccharomycetales TaxID=4892 RepID=A0A161HLQ6_9ASCO |
| Q6C111_YARLI | 33.28% | 661 | 1e-111 | YALI0F20174p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F20174g PE=4 SV=1 |
| A0A1E4TI06_9ASCO | 32.41% | 648 | 2e-102 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_44945 PE=4 SV=1 |
| MDL2_YEAST | 28.31% | 544 | 5e-49 | ATP-dependent permease MDL2, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MDL2 PE=1 SV=3 |
| A0A1D8PQ34_CANAL | 26.31% | 612 | 5e-45 | Mdl2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MDL2 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0776
Protein family membership
None predicted.
Domains and repeats
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Domain
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Domain
1
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1965
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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TRANSMEMBRANE (Tran...)
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mobidb-lite (disord...)
Protein sequence
>MCA_02188_1 MVGEYFEKSSKSNHFKKNPELHNDFLNVNQDAAGKRRSSSIVSNNDSDSQYYNNHLKVITPLKNKTKSSAKSSPASSVYY YGSESPGSFPLTTFTKETSTSSSSTSNQSSSDTNKPKQKLKLESNLDNHPPTVGILNTNFKFGTGSATTVPANRSSNQSD SENSGPKIKFVEPESKTESSVNSTEEGNNNNNLAVLSEPSENNNSLLIKQQQSSNAINIFVSSETSPSKTDRENTTILYF DIDTDEDDGYKEHVEQTKSNNKNNISAQNDNVNHGSDQSALSIPTLNDISTSASTVAEGATNFLQTIKSHCSTLSGLSHL PKLSLERTTTNATATSRVSFSALQLPLQEISINGGESSSAQKPYQRHRRFPSSTITVGNNGFSEAEAIICPDIPVEETNA ILRQVNIPNDSINILTLYRYATIKDLIILSVAYLFQIIAGAALPLTNVLVGKITTTFADLISGDVDKAEYTDKVISLTMH FIYIGAGIGVSCYISIYILGNRGEVIAGRTRKAFFQSLLRQNMAYFEYVGQGEIARRLRSDMQQIQEAISDNSGMAVSHT ATFVSAIIVGFLSSWNISLTIIALLCSIFVAYMLAMTYIRKLDNSITMELKEGRKVVSQTIDSIHTTTALGTSKFHAQRF YQHLKRASVPTEIQIKLFALLIGFIWFIVYVAYGLAFWKGFKEVDDDNIGAGELLTTISSLIIAGFALSGAYPVVQGLRN GIEAARNIYETIDRPSPIDPLEEGKYIPTITRFNVNNNSNSHNSITKNGVGRIRGLVEFKEVRLRYPVVPSKLVLDNVDL TINANECVAIVGPQGCGKSAILSLLERYYDPVGGQIFVDKVDISEYNVQYLRQQIAIVTQEAVLFQGTIFDNIVQGLKGT KYETLDSKVQEEMVIKVCREVNAWGFILAMDLGLYSLVGERGCNLTISQRQRVSLARVIISRPAILLLDEATSALNPRSS KCVFTSLAKLRRTAHTTIIMVTSSLSTILQADRVVVMGRGRIVDEGSHWELVARNSWYSDFTENQEYSQKRQQRQQKIRH QHHISTANVDYPDSNSNAVIMFNKERQLVGRPVVGQMGNSASFQHELLHWNNCIYEEVDEDDNSAPDIGTIYTTNLGPGL NNRQDYGSNNNNSFGHSRFFGGSSSNSNNSIYNTNNNVYNASHTVGYDFTGKGSKNETLYKSGGGTIKTTTERPKKRVAK PIQLFSMASLFGMLIRINKEAHVELFFGEVAALICGIGYPTVCVFFARCMEALLQPDEDYAASKVTIQSYTIYIVILSAI QFVSNFGLFYLMGRASDKLVRKLRYTIFRHVLRMDIEFFDSDSADSESITLMLLDEANRLRNLAGNVFGMVQDSSVALFV GLFVVIAADWRLGLVASSLIPVLVACCYLRYTVHMNFQKQAKIAYERSAALATDAVAAVRELTAQGREQQFLDLYNWEIN TRIHQRHSWSLFTSVLYAASQGAVPLCLCLQVWLGSKLLGEDKIDIYQFYIAFITLLIAGQAIQAIFNFVPEINLAQESI GNIARLLDIIPEMDECSQTGIMINEDPPNYSALLSNNNSYNNYTRNPDYNEDFASPRLSPHNYRTFGVSEDYVKGKFEFR QVAFQYPFQPEYSVLQDVSFRIEPQQLAAIVGPEVNSSDRGAVLELLELFYKPHSGGIYLDGINIEELNLASYRRIIGYV NSKAIFLEGLSIKDNIMLGWKNLENNNILTDENDYYTTKRGGGGSNNNNNNKKGKKSKRSIIGGYFSGINIINNNNNNNG GEGNNYGRPMNGQQEENEQDGALVTACKICQIHDFIMGLPDGYDTVGGVMFRPSQKIRIALARAILRDPNILLIDDVFMS SLGGTSSLSNEDISTELEFDYSSSSSSSLQSSLEEEYHEQENKREEEETINNNNNNNFKKKKSNHPVRHRIYNVGSTRSE VSTILNAIKRASKGRTTILVTSNIKAAKQISDQMIYIERGQVISE
GO term prediction
Biological Process
GO:0006810 transport
GO:0055085 transmembrane transport
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Cellular Component
GO:0016021 integral component of membrane