Protein

MCA_02161_1

Length
866 amino acids

Gene name: APL4

Description: AP-1 complex subunit gamma-1

Browser: contigB:417374-419975+

RNA-seq: read pairs 4434, FPKM 63.2, percentile rank 70.4% (100% = highest expression)

Protein function

Annotation:APL4AP-1 complex subunit gamma-1
KEGG:K12391AP1G1 AP-1 complex subunit gamma-1
EGGNOG:0PFIJAPL4AP-1 complex subunit gamma-1
SGD closest match:S000006233APL4AP-1 complex subunit gamma-1
CGD closest match:CAL0000191386APL4Apl4p

Protein alignments

%idAln lengthE-value
MIA_03975_175.96%6240.0MIA_03975_1
A0A0J9XJM7_GEOCN74.00%6230.0Similar to Saccharomyces cerevisiae YPR029C APL4 Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex OS=Geotrichum candidum GN=BN980_GECA19s01803g PE=4 SV=1
A0A167D6M7_9ASCO74.01%6080.0Apl4p OS=Sugiyamaella lignohabitans GN=APL4 PE=4 SV=1
UniRef50_A0A167D6M774.01%6080.0Apl4p n=20 Tax=saccharomyceta TaxID=716545 RepID=A0A167D6M7_9ASCO
A0A060TFM3_BLAAD72.04%6080.0ARAD1D24332p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D24332g PE=4 SV=1
A0A1E3PLH7_9ASCO68.20%6100.0Adaptor protein complex AP-1 gamma subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46337 PE=4 SV=1
Q6CDT5_YARLI66.56%6040.0YALI0B21340p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B21340g PE=4 SV=1
A0A1E4TF43_9ASCO53.59%5990.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_106214 PE=4 SV=1
A0A1D8PSB0_CANAL50.65%6120.0Apl4p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=APL4 PE=4 SV=1
AP1G1_YEAST39.63%6461e-110AP-1 complex subunit gamma-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APL4 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5773

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 866

Detailed signature matches

  1. Family IPR017107
    Adaptor protein complex AP-1, gamma subunit
    1. PIRSF037094 (AP1_gamma)
  2. Domain IPR016024
    Armadillo-type fold
    1. SSF48371 (ARM repeat)
  3. Domain IPR011989
    Armadillo-like helical
    1. G3DSA:1.25.10.10
  4. Domain IPR002553
    Clathrin/coatomer adaptor, adaptin-like, N-terminal
    1. PF01602 (Adaptin_N)
  5. Domain IPR013041
    Coatomer/clathrin adaptor appendage, Ig-like subdomain
    1. SSF49348 (Clathrin ...)
  6. Domain IPR008152
    Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
    1. PF02883 (Alpha_adap...)
    2. SM00809 (alpha_adap...)
  7. Domain IPR008153
    Gamma-adaptin ear (GAE) domain
    1. PS50180 (GAE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:2.60.40...
  3. mobidb-lite (disord...)

Protein sequence

>MCA_02161_1
MTSLKQFIKAVRAAKTIADERTVIQKESAAIRTSFRGDSSDNYVRRQNVAKLLYLFTLGERTHFGQVECLKLLASARFSD
KRLGYLGTMLLLDEKQEVLTLLTNSLSNDLAHPNQYVVSLALCTLGNIASTEMARDLFKDIEKIISSSNPYLRKKAAICA
MRIIRRAPELDEIYIDKAKMLLNDKNHGVLLCGLALVTDLCVQDPEHIETFLPALPLLIKHLKTLSQSGYSPEHDVTGIS
DPFLQVKILRLLRIFGTGNAQASERMNDILTQIASNTDASKNVGNSILYEAVQTIFSIETDPALRVLGVNILGKFLTNKD
NNTRYVALNTLLQVIDSETTAVQRHRSTIIECLQDGDISIRRRALELSYALINEQNVRVLVRELLSFLETADTEFKAPLT
SQIAIAAEKYAPNRRWHIDTIIRMLKIAGSYTKENVLSSFVVLVINSPEFQLYTVQKLYSALKADITQEGLTLAAVWLIG
EYGNVLLKGGSYQPEESDPSSASAPSEPVTESDIVDLLDTVVSSSYASETVKEYVINALMKLTTRISSAKEIERIRRILD
QFNCDMDEEIQQRVAEYGALFKYDSVRRGVLEKMPAPELHHELSRRYEEEKQKKEAKKYPFKSKGKLNATSTGSSNKSTN
KNGSAAANDLLLDLMDDDNNNKNTPSTTTTALANNTDLLSDLFGSSSTPAASTQAQPSTNSKPVNNNILDLFNSPATTNS
ITTNTTTTTAPVGLASTNTIPSTVNSSNTSNLNISPIEAYNKSGFQVTLEPTNSEAGGMLIMARFHNHGSGNIEGINLQV
AVPKSQKLILKGISSNHLGPGETATQQLKVTGNPGSSVKLRLRVNYVLNGSLVQEQVDFNKFPIGL

GO term prediction

Biological Process

GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport

Molecular Function

GO:0005488 binding
GO:0008565 protein transporter activity

Cellular Component

GO:0005794 Golgi apparatus
GO:0030117 membrane coat
GO:0030131 clathrin adaptor complex