Protein

MCA_02159_1

Length
631 amino acids

Gene name: CDC23

Description: Anaphase-promoting complex subunit CDC23

Browser: contigB:404991-407077+

RNA-seq: read pairs 1154, FPKM 22.6, percentile rank 44.7% (100% = highest expression)

Protein function

Annotation:CDC23Anaphase-promoting complex subunit CDC23
KEGG:K03355APC8 anaphase-promoting complex subunit 8
EGGNOG:0PG1FCDC23Anaphase-promoting complex subunit
SGD closest match:S000001209CDC23Anaphase-promoting complex subunit CDC23
CGD closest match:CAL0000200782CDC23Anaphase promoting complex subunit

Protein alignments

%idAln lengthE-value
MIA_04036_172.55%5720.0MIA_04036_1
A0A0J9XEJ1_GEOCN64.13%5520.0Similar to Saccharomyces cerevisiae YHR166C CDC23 Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) OS=Geotrichum candidum GN=BN980_GECA10s03156g PE=4 SV=1
A0A1E3PKZ0_9ASCO58.04%5100.0Subunit of the anaphase-promoting complex/cyclosome OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51142 PE=4 SV=1
A0A060TJS3_BLAAD53.83%5480.0ARAD1D49126p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D49126g PE=4 SV=1
Q6CCC3_YARLI52.00%5500.0YALI0C10692p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C10692g PE=4 SV=1
UniRef50_Q6CCC352.00%5500.0YALI0C10692p n=6 Tax=Saccharomycetales TaxID=4892 RepID=Q6CCC3_YARLI
A0A167FYR7_9ASCO51.84%5174e-179Anaphase promoting complex subunit CDC23 OS=Sugiyamaella lignohabitans GN=CDC23 PE=4 SV=1
Q5A326_CANAL42.64%5989e-153Anaphase promoting complex subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC23 PE=4 SV=1
A0A1E4TM06_9ASCO42.55%5507e-150Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_21590 PE=4 SV=1
CDC23_YEAST36.22%5666e-116Anaphase-promoting complex subunit CDC23 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC23 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1062

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Repeat
1 100 200 300 400 500 631

Detailed signature matches

  1. Domain IPR007192
    Cdc23
    1. PF04049 (ANAPC8)
  2. Domain IPR011990
    Tetratricopeptide-like helical domain
    1. G3DSA:1.25.40.10
    2. SSF48452 (TPR-like)
  3. Domain IPR013026
    Tetratricopeptide repeat-containing domain
    1. PS50293 (TPR_REGION)
  4. Repeat IPR019734
    Tetratricopeptide repeat
    1. PS50005 (TPR)
    2. SM00028 (tpr_5)
    3. PF13181 (TPR_8)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.28...
  2. PF13414 (TPR_11)
  3. mobidb-lite (disord...)

Protein sequence

>MCA_02159_1
MESLDSDQTRSELQQLRLELLSSVYHLSERCLFQASKWSAEALNSLDLPETDKDPIQTIKLVDKPIVTDKEILAKTFFDC
HEYDRCAYLLRDTTTPLGLFLKLYALYISGEKKREEEHEGVLSPKDGTSPNRQVVRIIRELDEYFESHKPDPFLLYLHGV
ALIRQKKEKEALQKLVESVNMMPYNWSAWQEIYTCLDTIESLHSLIPSLPRHLMTRVFTVYAHQEFFQHEDIDLEELNDI
LTFMPTFNFLITQKALIHYHGLEYDESEAEFQQVLKSDPHRLDDMDTYSNILYVMERRPTLAFLAQLASSTDKFRPETCC
IIANYYSLKSEHEKAITYYQRALTLNRNCLSAWTLMGHEFVELKNTHAAIESYRHAIDVNKKDFRAWYGLGQAYEVLDMN
YYSLYYYQRAASIKPMDARMWQALGNCYERLGKYTDAILTYQRALYLSEMNDPTILLKLALIEEKCGYKDRAAKYMRRCL
FGTTDQSGFNNEEGGNPSDNLDSEADEGQGTTGEDGSATEMDERNQARMWLARYEMSRENWKKANEYAKGLLHGLPSEME
EARAIVKDTNSRLLGLLDKRGSDEKGKSVQAKGKEKSTTNFNGSSTATDNSQTDDDVNRVGFNNPLPGTGQ

GO term prediction

Biological Process

GO:0030071 regulation of mitotic metaphase/anaphase transition

Molecular Function

GO:0005515 protein binding

Cellular Component

GO:0005680 anaphase-promoting complex