Protein

MCA_02140_1

Length
436 amino acids

Gene name: MRM2

Description: rRNA methyltransferase 2, mitochondrial

Browser: contigB:342962-344360+

RNA-seq: read pairs 502, FPKM 14.2, percentile rank 32.7% (100% = highest expression)

Protein function

Annotation:MRM2rRNA methyltransferase 2, mitochondrial
KEGG:K15508MRM2 21S rRNA (uridine2791-2'-O)-methyltransferase [EC:2.1.1.168]
EGGNOG:0PH9VMRM221S rRNA (uridine(2791)-2'-O)-methyltransferase
SGD closest match:S000003104MRM2rRNA methyltransferase 2, mitochondrial
CGD closest match:CAL0000180659CAALFM_CR10260WA21S rRNA (Uridine2791-2'-O) methyltransferase

Protein alignments

%idAln lengthE-value
MIA_03843_155.56%3605e-132MIA_03843_1
A0A1E3PQV9_9ASCO45.53%3476e-9723S ribosomal RNA methyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_77235 PE=3 SV=1
UniRef50_A0A1E3PQV945.53%3471e-9323S ribosomal RNA methyltransferase n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A1E3PQV9_9ASCO
A0A0J9X559_GEOCN46.50%3579e-96Similar to Saccharomyces cerevisiae YGL136C MRM2 Mitochondrial 2' O-ribose methyltransferase OS=Geotrichum candidum GN=BN980_GECA03s03926g PE=3 SV=1
A0A060TJ57_BLAAD55.94%1431e-48ARAD1D44440p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D44440g PE=3 SV=1
Q6C3V1_YARLI68.52%1085e-44YALI0E31933p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E31933g PE=4 SV=1
MRM2_YEAST51.61%1248e-40rRNA methyltransferase 2, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MRM2 PE=1 SV=1
A0A1E4TJ28_9ASCO50.00%1245e-36Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_16771 PE=3 SV=1
A0A1D8PU64_CANAL36.45%1074e-1721S rRNA (Uridine2791-2'-O) methyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR10260WA PE=3 SV=1
A0A167C0G7_9ASCO39.77%882e-13Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase OS=Sugiyamaella lignohabitans GN=TRM7 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9907
Predicted cleavage: 43

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 436

Detailed signature matches

  1. Family IPR015507
    Ribosomal RNA large subunit methyltransferase E
    1. MF_01547 (RNA_methy...)
  2. Domain IPR029063
    S-adenosyl-L-methionine-dependent methyltransferase
    1. SSF53335 (S-adenosy...)
  3. Domain IPR002877
    Ribosomal RNA methyltransferase FtsJ domain
    1. PF01728 (FtsJ)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. NON_CYTOPLASM... (N...)
  4. SIGNAL_PEPTIDE (Sig...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. mobidb-lite (disord...)

Protein sequence

>MCA_02140_1
MIRLQRVNPAKNSSCALLTSCTSLFHSSARSNRLLSFSKYSTICRPSNTQTFRKNFRPSLLSSSAPCCIFETISDHQQIR
WKSSSSTKWLSRQSKDKFTARARVEGLMSRAAYKLIELDEKYRLFKKGMTIVDLGFAPGSWSQVAAKRVLPGGRVIGVDI
LPCRPPRGVSAIQGNFLSKGVQDELKLLLENPLAGQQNSVLKKSGKKQPDEVVDNDSNIPQGRGNFTEEELKNFEVLGDL
FDKVSYIELERRESAQLDAAAEANRIKEEEEKQEQQNTSTNNENNIVSEDTKKSQSEETAQQKKQGSSHKYSVDVVLSDM
CEPWPQTTGFWLRTINDPFLRMMNTSGNALRDHTLSIDLCDAALMFALDTLKPGGKFICKFYTGSEDRFLEARLKNAFKH
VKREKPSASRSESRELYFVCTGKLPNATRKSVFRLK

GO term prediction

Biological Process

GO:0001510 RNA methylation
GO:0032259 methylation

Molecular Function

GO:0008168 methyltransferase activity

Cellular Component

None predicted.