Protein

MCA_02123_1

Length
1,229 amino acids

Gene name: PRP16

Description: Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

Browser: contigB:300743-304433+

RNA-seq: read pairs 775, FPKM 7.8, percentile rank 22.0% (100% = highest expression)

Protein function

Annotation:PRP16Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16
KEGG:K12815DHX38 pre-mRNA-splicing factor ATP-dependent RNA helicase DHX38/PRP16 [EC:3.6.4.13]
EGGNOG:0PHRDPRP16factor ATP-dependent RNA helicase PRP16
SGD closest match:S000001794PRP16Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16
CGD closest match:CAL0000193710CAALFM_CR02590CADEAH-box RNA helicase

Protein alignments

%idAln lengthE-value
MIA_05471_175.84%9270.0MIA_05471_1
A0A0J9XI03_GEOCN72.79%8820.0Similar to Saccharomyces cerevisiae YER013W PRP22 DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase OS=Geotrichum candidum GN=BN980_GECA18s00395g PE=4 SV=1
A0A060T7K3_BLAAD65.53%9080.0ARAD1C22484p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C22484g PE=4 SV=1
A0A161HNH0_9ASCO67.21%9150.0DEAH-box RNA helicase PRP16 OS=Sugiyamaella lignohabitans GN=PRP16 PE=4 SV=1
UniRef50_C5GBH768.02%8630.0Adenosinetriphosphatase n=26 Tax=Eukaryota TaxID=2759 RepID=C5GBH7_AJEDR
Q6CF95_YARLI60.88%8410.0YALI0B09053p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B09053g PE=4 SV=1
A0A1D8PS92_CANAL50.11%9260.0DEAH-box RNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR02590CA PE=4 SV=1
PRP16_YEAST54.59%7730.0Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRP16 PE=1 SV=2
A0A1E4TMF7_9ASCO43.67%8130.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_43522 PE=4 SV=1
A0A1E3PNS0_9ASCO46.32%6520.0ATP-dependent RNA helicase DHX8 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_40141 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2989

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1229

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  3. Domain IPR011545
    DEAD/DEAH box helicase domain
    1. PF00270 (DEAD)
  4. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
  5. Domain IPR007502
    Helicase-associated domain
    1. SM00847 (ha2_5)
    2. PF04408 (HA2)
  6. Domain IPR011709
    Domain of unknown function DUF1605
    1. PF07717 (OB_NTP_bind)
  7. SITE IPR002464
    DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
    1. PS00690 (DEAH_ATP_H...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd00046 (DEXDc)
  4. cd00079 (HELICc)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. putative Mg++ bind...
  3. nucleotide binding...
  4. ATP-binding site c...

Protein sequence

>MCA_02123_1
MSKNAGSSDYLHSLAEEIAKQLNRTVPNETLAKQVLNFAKNLPNKEAFINACRAFGKFDNVFLESVYANAQQQKAFVTKS
KTSDVKIKIEPEQSTLHYDDDKNKIDFDKIKRESPADSKDSKHGLNRLVKKIKLESPDVKIIKEDPEDHAVVKQEPRDNS
TKVTKPVFRKMAHSSSTASRRAHSFDEENDENMVKPSSLSSTARDKLAEIRRSRENSHSDSRSSHYDDRDREYRKYRDDR
RYRSDRDRERDRNSPRDRDRDRDRYRDRDRYREDDRYDNRHRSDRYRDSYRSNRDSRNNTRNYEEPKENLPGDDEYDEES
LRALDRDWYTGDDFGHAVGDDAHNPFGDGMNYAVEEQALEKRVTNRIANIARQKQQDSEMWEKNRLATSGFAGSNEEINL
NFDDDEDKKTHVMVHDLRPPFLDGQQVFSKIKDPISAIKDPQSDMAIIAKKGSLLVREHREKRERAKQAKDSASVAGTIL
GNVMGVKNEEDPDRSDGEGETTSNSSSEKFSDHLKKSKGVSEFSKKLTLKQQRQYLPAFAVRDELLQVIRDNQVVIVIGE
TGSGKTTQLTQFLYEDGYGKQGMIGCTQPRRVAAISVAKRVSEEMEVKLGSTVGYAIRFEDNTSENTVIKYMTDGVLLRE
SLTDADLNKYSCIIMDEAHERALNTDVLMGLFKKILPRRRDLKLIITSATMNAERFSQFYGNSPQFTIPGRTFPVDIQNH
TTPVEDYVDAAVKQILSIHMKNGPGDILVFMTGQEDIEVTCEVLKEKLDLLDNPPPLDILPIYSQLPTDLQAKIFEPAKK
GTRKVIVATNIAETSLTVDGISYVVDCGYSKVKVYNPKIGMDSLQLAPISLANANQRSGRAGRTGKGIAYRLYTQKAQID
EMYPQAIPEIQRTNLANTLLLLKSLGVDNLLEFDFMDAPPTDIMTSSLYDLWALGALDNLGHLTKLGEKMSKLPMEPSLA
KILILSLDYGCTEEILTIVSMLSVPSVFYRPKERQEEADAAREKFFVAESDHLTLLHVFKLWMMNKCSDAWCAKHFLHPR
ALRRAKEVRDQLVYILREYKNDMKSCGSDWDIVRKCICSGFFPQAARVRGLGEYMNLRTNVIMQLHPTSALYGLGYLPEY
VIYHELVLTSKEYMSVVTAVDPFWLAKLGGVFYSIKEKGFSSITGKSIDNSYNEHHDKILQDLERDRKIYEESMNKDSAS
NRNNKKKSKKSSAVVMAPGRKGFGSRRGF

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding

Cellular Component

None predicted.