Protein

MCA_02116_1

Length
792 amino acids


Gene name: NDC80

Description: Kinetochore protein NDC80

Browser: contigB:279158-281537-

RNA-seq: read pairs 632, FPKM 9.8, percentile rank 25.7% (100% = highest expression)

Protein function

Annotation:NDC80Kinetochore protein NDC80
KEGG:K11547NDC80 kinetochore protein NDC80
EGGNOG:0PG2ZNDC80Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (By similarity)
SGD closest match:S000001406NDC80Kinetochore protein NDC80
CGD closest match:CAL0000189198NDC80Probable kinetochore protein NDC80

Protein alignments

%idAln lengthE-value
A0A167FTK1_9ASCO28.66%7642e-74Ndc80p OS=Sugiyamaella lignohabitans GN=NDC80 PE=4 SV=1
UniRef50_A0A167FTK128.66%7645e-71Ndc80p n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167FTK1_9ASCO
A0A0J9XHS6_GEOCN29.60%6421e-65Similar to Saccharomyces cerevisiae YIL144W TID3 Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p) OS=Geotrichum candidum GN=BN980_GECA18s00362g PE=4 SV=1
MIA_05469_129.06%5544e-55MIA_05469_1
A0A060T258_BLAAD28.60%5701e-52ARAD1C22528p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C22528g PE=4 SV=1
NDC80_YEAST26.62%5865e-40Kinetochore protein NDC80 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NDC80 PE=1 SV=1
NDC80_YARLI26.19%5692e-33Probable kinetochore protein NDC80 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=NDC80 PE=3 SV=1
A0A1E3PPR7_9ASCO27.27%5068e-30Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49860 PE=4 SV=1
A0A1E4THJ1_9ASCO25.00%6363e-28Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31927 PE=4 SV=1
NDC80_CANAL50.42%1197e-28Probable kinetochore protein NDC80 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NDC80 PE=3 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9878
Predicted cleavage: 196

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. PF03801 (Ndc80_HEC)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_02116_1
MSFPTGPPGSNSSNKPTNRASLIPSSISRPSTVRSLNGPPMSVARHSMINSNSNIGLSMPQRGPFNSRSSIAPGSSRQSA
FGTPGYQYNPSSARAPPSFSNNSFQQQQIYGSGGNNSTFNDSFNQPYISGTTGSSVPEMVAASMQRTNVRRSTLNPGNAS
INGIRKNPRQSYLPNTRPRKSVAPIPSTPLSSARSTVDKKQQTQMQQHIEQFLQANDFEKETQITITPKLLKSPEQKNFV
TMFKWLYHRIDPGYLFTKSIESELFFLLKTLNYPNLDSINKSQASAVGGFQWPSYLAMLYWLVQLIESLETQPYSLSKIL
DGQQAEESLDQLDSPIDYLHLSFQLRAYKRFLANRDYESDVIIEEMNERLQEYIKPELDKQEQIQNEIAQMQEELEKKST
EDDIENLETLSAHLTLDTNNYEEYLKSYEQKFQKRKATNERLAEKIQLTEEQLNQTRLENQELKDNLKANGKDLETIDNL
NSQLAEYRAQKQELELEAEEISNTLTKRREEATEILKEIEARHRKYNELVQYIKHDVRGSSILKKKLEEDPTFFDITLDS
PLADENLGKSMLELLKGKDFYNAIRPILIECRKEIGENIHATSEEVIKNQERFDRLSESLREKTEQLDTLENRLNMANAT
YKTKYDTYNNDQQAYKLEIETLEGQIAKLIRKQDPAYLAELEERAQKLKTYYETLQKTAKTKCTATQSHVDKYSSMALSF
RLYVNESIFNHEGKVVSELEKYDNGAILDEYQVFEQQELKRKASSSSASKNQLEDSGNDENETNNNSNNDKS

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.