Protein

MCA_02015_1

Length
350 amino acids

Gene name: GAL7

Description: Galactose-1-phosphate uridylyltransferase

Browser: contigB:33733-34786-

RNA-seq: read pairs 9903, FPKM 348.6, percentile rank 92.8% (100% = highest expression)

Protein function

Annotation:GAL7Galactose-1-phosphate uridylyltransferase
KEGG:K00965galT UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
EGGNOG:0PFUGGAL7galactose-1-phosphate uridylyltransferase
SGD closest match:S000000222GAL7Galactose-1-phosphate uridylyltransferase
CGD closest match:CAL0000182951GAL7Galactose-1-phosphate uridylyltransferase

Protein alignments

%idAln lengthE-value
A0A0J9XIW8_GEOCN57.35%3471e-152Galactose-1-phosphate uridylyltransferase OS=Geotrichum candidum GN=BN980_GECA22s01396g PE=3 SV=1
MIA_05608_154.50%3674e-151MIA_05608_1
A0A060T9P6_BLAAD55.21%3555e-151Galactose-1-phosphate uridylyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D13464g PE=3 SV=1
A0A1E4THW3_9ASCO54.73%3493e-147Galactose-1-phosphate uridylyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3043 PE=3 SV=1
UniRef50_A0A1E4THW354.73%3499e-144Galactose-1-phosphate uridylyltransferase n=4 Tax=saccharomyceta TaxID=716545 RepID=A0A1E4THW3_9ASCO
A0A167EC78_9ASCO54.37%3553e-144Galactose-1-phosphate uridylyltransferase OS=Sugiyamaella lignohabitans GN=GAL7 PE=3 SV=1
GAL7_YEAST50.43%3512e-131Galactose-1-phosphate uridylyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GAL7 PE=1 SV=4
A0A1E3PTC9_9ASCO52.59%3481e-130Galactose-1-phosphate uridylyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45156 PE=3 SV=1
Q6C0K3_YARLI52.72%3497e-130YALI0F23947p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F23947g PE=4 SV=1
A0A1D8PCM2_CANAL49.58%3592e-125Galactose-1-phosphate uridylyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GAL7 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0547
Predicted cleavage: 12

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 350

Detailed signature matches

  1. Family IPR001937
    Galactose-1-phosphate uridyl transferase, class I
    1. PIRSF000808 (GalT)
    2. TIGR00209
  2. Domain IPR011146
    HIT-like domain
    1. SSF54197 (HIT-like)
    2. G3DSA:3.30.42...
  3. Domain IPR005849
    Galactose-1-phosphate uridyl transferase, N-terminal
    1. PF01087 (GalP_UDP_t...)
  4. Domain IPR005850
    Galactose-1-phosphate uridyl transferase, C-terminal
    1. PF02744 (GalP_UDP_tr_C)
  5. SITE IPR019779
    Galactose-1-phosphate uridyl transferase, class I His-active site
    1. PS00117 (GAL_P_UDP_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00608 (GalT)

Residue annotation

  1. dimer interface cd...
  2. active site cd00608

Protein sequence

>MCA_02015_1
MPDFNLPHRRYNPLTKEWLLVSPHRTQRPWQGQQEKTASPSGVKYVPDCYLCPGNSRASGGKNPIYKETFVFQNDYSAVM
PKSSGDTNRQENSGVDSLFRAEEVNGRCMVICYSPDHDVTLPQMSQSQIIKVIETWQSVYQSSLDDPDIKYCQIFENKGS
VMGCSNPHPHGQAWMTNIVPNEPAKEHESFKEYFEKNKSGLLSDYIKAEIEKKDRIVAINDGFIALVPFWAIWPYEIMVL
PRKQIARITELDSQGKKHLAEVLSQITIKYDNLFKTSFPYSMGIHQACSDQSAEDSIDHLHFHFYPPLLRSASVKKFLVG
FEMLGMPQRDLTPEKAAATLRDLSGEKRFD

GO term prediction

Biological Process

GO:0006012 galactose metabolic process
GO:0033499 galactose catabolic process via UDP-galactose

Molecular Function

GO:0003824 catalytic activity
GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity
GO:0008270 zinc ion binding

Cellular Component

None predicted.