Protein

MCA_02005_1

Length
254 amino acids

Gene name: SEC53

Description: Phosphomannomutase

Browser: contigB:19138-19903-

RNA-seq: read pairs 7457, FPKM 361.3, percentile rank 92.9% (100% = highest expression)

Protein function

Annotation:SEC53Phosphomannomutase
KEGG:K17497PMM phosphomannomutase [EC:5.4.2.8]
EGGNOG:0PHHPSEC53phosphomannomutase
SGD closest match:S000001849SEC53Phosphomannomutase
CGD closest match:CAL0000183926PMM1Phosphomannomutase

Protein alignments

%idAln lengthE-value
MIA_05596_185.38%2531e-165MIA_05596_1
A0A0J9XBR0_GEOCN79.20%2505e-153Phosphomannomutase OS=Geotrichum candidum GN=BN980_GECA08s03299g PE=3 SV=1
A0A060T5L4_BLAAD75.70%2519e-147Phosphomannomutase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B07700g PE=3 SV=1
Q6C985_YARLI75.60%2508e-143Phosphomannomutase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D13112g PE=3 SV=1
A0A167E569_9ASCO73.02%2522e-142Phosphomannomutase OS=Sugiyamaella lignohabitans GN=SEC53 PE=3 SV=1
PMM_YEAST72.22%2529e-142Phosphomannomutase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC53 PE=1 SV=1
UniRef50_P0728372.22%2522e-138Phosphomannomutase n=588 Tax=Eukaryota TaxID=2759 RepID=PMM_YEAST
PMM_CANAL75.30%2471e-140Phosphomannomutase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PMM1 PE=1 SV=1
A0A1E4TK73_9ASCO72.51%2518e-139Phosphomannomutase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_82609 PE=3 SV=1
A0A1E3PP26_9ASCO70.75%2531e-133Phosphomannomutase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45287 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5693

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 254

Detailed signature matches

  1. Family IPR006379
    HAD-superfamily hydrolase, subfamily IIB
    1. TIGR01484
  2. Family IPR005002
    Phosphomannomutase
    1. SFLDG01143 (C2.B.3:...)
    2. PF03332 (PMM)
    3. cd02585 (HAD_PMM)
  3. Domain IPR023214
    HAD-like domain
    1. SSF56784 (HAD-like)
    2. G3DSA:3.40.50...
Unintegrated signatures no IPR
Unintegrated signatures
  1. SFLDF00445 (alpha-p...)
  2. SFLDG01140 (C2.B:_P...)

Residue annotation

  1. HAD signature moti...
  2. SFLDG01143
  3. active site cd02585
  4. SFLDF00445
  5. SFLDG01140
  6. HAD signature moti...
  7. HAD signature moti...

Protein sequence

>MCA_02005_1
MTVKPFSEREFPDSICLFDVDGTLTPARLQISSDMKSLLQQLRNKCTIGFVGGSDLAKQKEQLGEDVIDQFDFAFSENGL
TAYKLGEKMASQSFISWIGDEKYNKLVIFILKYLSEIELPKRRGTFIEFRNGMINVSPIGRNASVDERNEFEAYDKVHKI
REKMVQALKDEFPDYGLTYSIGGQISFDVFPTGWDKTYCLQYVEPEGFKNIHFFGDKSYKGGNDYEIYTDPRTIGHAVSS
PEDTAKILKEIFFQ

GO term prediction

Biological Process

GO:0009298 GDP-mannose biosynthetic process

Molecular Function

GO:0004615 phosphomannomutase activity

Cellular Component

GO:0005737 cytoplasm