Protein

MCA_01986_1

Length
913 amino acids

Browser: contigA:6031700-6034442-

RNA-seq: read pairs 1850, FPKM 25.0, percentile rank 47.6% (100% = highest expression)

Protein function

KEGG:K05012CLCN3_4_5 chloride channel 3/4/5
EGGNOG:0PKWPFGSG_05451Chloride channel
SGD closest match:S000003801GEF1Anion/proton exchange transporter GEF1
CGD closest match:CAL0000193105orf19.5880Uncharacterized protein

Protein alignments

%idAln lengthE-value
MIA_06347_166.09%8080.0MIA_06347_1
A0A0J9XGZ1_GEOCN57.59%9220.0Chloride channel protein OS=Geotrichum candidum GN=BN980_GECA16s00340g PE=3 SV=1
UniRef50_A0A0J9XGZ157.59%9220.0Chloride channel protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XGZ1_GEOCN
Q6C6J6_YARLI47.32%8200.0Chloride channel protein OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E09015g PE=3 SV=1
A0A060T4T7_BLAAD44.87%7800.0Chloride channel protein OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B05742g PE=3 SV=1
A0A1E4TI73_9ASCO41.12%7492e-178Chloride channel protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_55324 PE=3 SV=1
A0A1E3PEH6_9ASCO38.31%8382e-167Chloride channel protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_79986 PE=3 SV=1
A0A167DMV6_9ASCO45.90%5499e-136Chloride channel protein OS=Sugiyamaella lignohabitans GN=GEF1 PE=3 SV=1
A0A1D8PJZ9_CANAL34.44%7812e-133Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5880 PE=4 SV=1
GEF1_YEAST30.97%7468e-81Anion/proton exchange transporter GEF1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GEF1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0052

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 913

Detailed signature matches

  1. Family IPR001807
    Chloride channel, voltage gated
    1. PR00762 (CLCHANNEL)
    2. PF00654 (Voltage_CLC)
  2. Domain IPR014743
    Chloride channel, core
    1. SSF81340 (Clc chlor...)
    2. G3DSA:1.10.30...
  3. Domain IPR000644
    CBS domain
    1. PS51371 (CBS)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:3.10.58...
  3. NON_CYTOPLASM... (N...)
  4. SSF54631 (CBS-domai...)
  5. TMhelix
  6. TRANSMEMBRANE (Tran...)
  7. cd03684 (ClC_3_like)
  8. cd04591 (CBS_pair_E...)
  9. mobidb-lite (disord...)

Residue annotation

  1. putative Cl- selec...
  2. putative pore gati...
  3. putative H+/Cl- co...

Protein sequence

>MCA_01986_1
MSQNDHRNSFSVEHTDYDVDDLPSHTSDLESHHENDSISAFYNNGSNVQSKKSYLSSLKSFFIPSTRSNFSKSFSSQPIT
PTHHQSFQPLLSHNDDYDESFTNSDINQHNISSFPNLTESYHNQSRKFYQDDDRTIAYEDMTAIDWQYEYTKERVRQEKL
ESTPGVYGKLIWLLDVSHIWIVLILTGIMTAIVAAYIDIVSRWLADIKFGYCSDAFYLPKDFCCSGIDQVDKCEKWITWE
KSFHIENNVVGSYATAYIFYILFAIFFAAAACILVMFYAPHSRFSGIAEIKTILSGFIIRDLLGFKTLIFKATGLILVVG
AGLWVGKEGPLVHVACCCANVTTFIFPQLYHNEALKREILSAAASAGISVAFGSPIGGVLFSLEQMSYYFPERTLWNSFV
AAMVAAVTLQFINPFRSGNLVLFQVIYDRLWHRFELVPFAVIGVLGGIYGALFTSLNIKIANWRRKSKFISSKPLLEVVL
VGLVTGLVTYPIVYTRIPASLSLSHMFQECSNNVPGHLCDDSYWKSSSMVLFIAGVQGFFLTAYTFGINIPAGIIMPSML
NGALIGRAIGIVMNTWQKNHSKFVLFESCPPDGPCITPGVYALVGAASTLCGVTHLTVSTVVIMFELTGALTYVIPIMTG
VMVSKWVSDYFNHKGIYESWIRFSEYPFLDNHDDQPIPDVTVESIMTKVEDLTLIPADSSTVGSLKQILELSSSQGFPIT
KSVDDMTLVGYITRAELKHAITDLPLHTSNDIPCSFSKPLESRQSSTFDQSHDYINHGNDSIYDFVSSVDQPSSFHNSHH
DNSTQPISLYRYTEHAPITLSYLSRLQLAASMFQKLGLRFILFSHKGQLKGLLTRKDVWQLLNSFDTDAENIDTLSESSR
NARGRLLNTISFSMRGLDNNGFSNMSQEEGYRS

GO term prediction

Biological Process

GO:0006821 chloride transport
GO:0055085 transmembrane transport

Molecular Function

GO:0005216 ion channel activity
GO:0005247 voltage-gated chloride channel activity

Cellular Component

GO:0016020 membrane