Protein

MCA_01981_1

Length
566 amino acids

Browser: contigA:6023777-6025478+

RNA-seq: read pairs 2079, FPKM 45.3, percentile rank 63.2% (100% = highest expression)

Protein function

KEGG:K09584PDIA6 protein disulfide-isomerase A6 [EC:5.3.4.1]
EGGNOG:0PG1GPGUG_03063disulfide isomerase
SGD closest match:S000005814MPD1Protein disulfide-isomerase MPD1
CGD closest match:CAL0000188924orf19.3920Protein disulfide isomerase

Protein alignments

%idAln lengthE-value
MIA_05677_139.02%5517e-115MIA_05677_1
A0A060T217_BLAAD41.11%2704e-45ARAD1C25542p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C25542g PE=4 SV=1
UniRef50_A0A060T21741.11%2709e-42ARAD1C25542p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T217_BLAAD
Q6BZZ7_YARLI28.45%4647e-32YALI0F29381p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F29381g PE=4 SV=1
A0A1E4THV0_9ASCO35.77%2603e-32Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_122300 PE=4 SV=1
A0A161HMB7_9ASCO31.85%2923e-29Protein disulfide isomerase MPD1 OS=Sugiyamaella lignohabitans GN=MPD1 PE=4 SV=1
A0A1E3PJN8_9ASCO35.35%1981e-28Thioredoxin-like protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_14830 PE=4 SV=1
MPD1_YEAST32.37%3121e-25Protein disulfide-isomerase MPD1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MPD1 PE=1 SV=1
A0A1D8PNX4_CANAL37.75%2046e-24Protein disulfide isomerase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3920 PE=4 SV=1
A0A0J9XBV2_GEOCN30.29%3072e-23Similar to Saccharomyces cerevisiae YOR288C MPD1 Member of the protein disulfide isomerase (PDI) family OS=Geotrichum candidum GN=BN980_GECA09s02617g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2652

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 566

Detailed signature matches

  1. Domain IPR012336
    Thioredoxin-like fold
    1. SSF52833 (Thioredox...)
  2. Domain IPR013766
    Thioredoxin domain
    1. PF00085 (Thioredoxin)
    2. PS51352 (THIOREDOXIN_2)
  3. SITE IPR017937
    Thioredoxin, conserved site
    1. PS00194 (THIOREDOXIN_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.30.10
  2. NON_CYTOPLASM... (N...)
  3. PR00421 (THIOREDOXIN)
  4. SFLDG00345 (PDI-like)
  5. SIGNAL_PEPTIDE (Sig...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. SIGNAL_PEPTID... (S...)
  9. SignalP-noTM
  10. cd03002 (PDI_a_MPD1...)
  11. mobidb-lite (disord...)

Residue annotation

  1. catalytic residues...

Protein sequence

>MCA_01981_1
MLAKILNLFFLVTLASASFYTNSPVLELNSRNFKSKVLDTQHLTLVEFYAPWCGHCQNLKPEYIKAAKLLKGLANLAAIN
CDDSSNKKLCSQYGVQGFPTLKIFGPSYVSSSDKKKVLSKRSKFLDDYNGARTAKAIRDTINYRLPSHAKVINSVKKLNE
KFIDHPRVLLIAGSSSPGSNVPSAFKSLSIDYFRNSTDKSLNPIFAFVPSRNQADAFKVLKYNKQPDRKSSLLVIYEAGD
LENPIFYEGAMKKELISKFISDYLSPTDLLTGRVPPKKIKAQSKRGNKVDAKKSTVSTNQKQPEKSISSESTSTKSRSEI
NVGKKKEKKNTIPDASSAKTIEKTEESKVTSTPPPSQDEDTSVVEPGITGVSTAGPRVGKSTKLYANRIYTTDDLRSYCF
QPDSKPCLLAVLSVNGQISGMRTFNNVEKHLPISFRGGHDSINWIHMIDTTEDDTSGDDEVAYMARLFGLKPYFPSPWKV
QDNKSKYENLNKVGLGDMKPSDNWDHPPAAVYINGRENYIINFPANTEVNTDTVTKFLIACSNETNKHERKKVPNGFFVV
KRHDEL

GO term prediction

Biological Process

GO:0045454 cell redox homeostasis

Molecular Function

None predicted.

Cellular Component

None predicted.