Protein
MCA_01962_1
Length
506 amino acids
Gene name: CYS4
Description: Cystathionine beta-synthase
Browser: contigA:5976539-5978159+
RNA-seq: read pairs 13453, FPKM 327.9, percentile rank 92.4% (100% = highest expression)
Protein function
| Annotation: | CYS4 | Cystathionine beta-synthase | |
|---|---|---|---|
| KEGG: | K01697 | CBS | cystathionine beta-synthase [EC:4.2.1.22] |
| EGGNOG: | 0PFT3 | CYS4 | Cystathionine beta-synthase |
| SGD closest match: | S000003387 | CYS4 | Cystathionine beta-synthase |
| CGD closest match: | CAL0000179764 | CYS4 | Cystathionine beta-synthase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_06386_1 | 83.66% | 508 | 0.0 | MIA_06386_1 |
| A0A0J9XI14_GEOCN | 82.35% | 510 | 0.0 | Cystathionine beta-synthase OS=Geotrichum candidum GN=BN980_GECA19s01484g PE=3 SV=1 |
| A0A1E3PEJ6_9ASCO | 71.83% | 504 | 0.0 | Cystathionine beta-synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47638 PE=3 SV=1 |
| Q6C6J2_YARLI | 71.65% | 515 | 0.0 | Cystathionine beta-synthase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E09108g PE=3 SV=1 |
| A0A060TDD2_BLAAD | 74.10% | 498 | 0.0 | Cystathionine beta-synthase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D42790g PE=3 SV=1 |
| A0A167EKW8_9ASCO | 73.61% | 451 | 0.0 | Cystathionine beta-synthase OS=Sugiyamaella lignohabitans GN=CYS4 PE=3 SV=1 |
| A0A1E4T9X4_9ASCO | 66.94% | 496 | 0.0 | Cystathionine beta-synthase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_124344 PE=3 SV=1 |
| Q59T95_CANAL | 64.03% | 506 | 0.0 | Cystathionine beta-synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CYS4 PE=3 SV=1 |
| UniRef50_F2QR13 | 63.67% | 501 | 0.0 | Cystathionine beta-synthase n=5 Tax=Saccharomycetales TaxID=4892 RepID=F2QR13_KOMPC |
| CBS_YEAST | 56.65% | 519 | 1e-161 | Cystathionine beta-synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CYS4 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.2135
Protein family membership
- Cystathionine beta-synthase (IPR005857)
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
400
450
506
Detailed signature matches
no IPR
Unintegrated signatures
Residue annotation
-
dimer interface cd...
-
catalytic residue ...
-
pyridoxal 5'-phosp...
Protein sequence
>MCA_01962_1 MTESKPQILDSILDQIGDTPLVRLNKIPQSLGIKAQFLVKVELFNSGGSVKDRIAKRMVLEAEKDGRLKPGYTLIEPTSG NTGIGLALVGAVRGYRTIITLPEKMSNEKVSVLKALGAEIVRTPTEAAWDSPESHIGVAKRLEKEIPNAVILDQYSNVNN PLAHEYGTGEEIWEQTGGKINYFVAGAGTGGTITGIAKALKNHDPKIKVIGADPKGSILALPESLNSGITSYQVEGIGYD FIPEVLDREIVDEWVKTEDRESFLLARRLIKEEGILVGGSSGSALAAAIKVAKEQNLTEDDVVVVLLPDSVRSYLTKFID DDWMKYNGFLDEETLEAQSQKKKQYKGATIADLNLKPVVTVKTSSPVSSAIEILQKNGFDQLPVLNEQGKLTGLVTLGNL LSYLSSGRAKTTTPVDKVMIDFRKLDEFTSKRPEESISIGTPAPSKKTSNNFAEITVDTPLSALNNFFEHKSSAIVTERD GNTLKPVHVVTKVDLLAYLVKNGGLE
GO term prediction
Biological Process
GO:0019343 cysteine biosynthetic process via cystathionine
Molecular Function
GO:0004122 cystathionine beta-synthase activity
Cellular Component
GO:0005737 cytoplasm