Protein

MCA_01953_1

Length
425 amino acids

Gene name: NPA3

Description: GPN-loop GTPase 1

Browser: contigA:5966105-5967383-

RNA-seq: read pairs 1393, FPKM 40.4, percentile rank 60.5% (100% = highest expression)

Protein function

Annotation:NPA3GPN-loop GTPase 1
KEGG:K06883uncharacterized protein
EGGNOG:0PFDSPGUG_00355XPA-binding protein
SGD closest match:S000003833NPA3GPN-loop GTPase 1
CGD closest match:CAL0000183311orf19.6463GTPase

Protein alignments

%idAln lengthE-value
MIA_06318_164.02%4288e-170MIA_06318_1
A0A0J9XFL2_GEOCN64.96%4112e-163Similar to Saccharomyces cerevisiae YJR072C NPA3 Member of the conserved GPN-loop GTPase family OS=Geotrichum candidum GN=BN980_GECA13s03024g PE=4 SV=1
A0A060T8P5_BLAAD71.79%3121e-153ARAD1C30602p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C30602g PE=4 SV=1
A0A1E3PQD7_9ASCO70.32%3101e-148Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45552 PE=4 SV=1
A0A1D8PR52_CANAL65.53%3226e-147GTPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6463 PE=4 SV=1
Q6C525_YARLI63.75%3311e-143YALI0E21626p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E21626g PE=4 SV=1
A0A167ENV4_9ASCO70.51%2953e-143GTPase NPA3 OS=Sugiyamaella lignohabitans GN=NPA3 PE=4 SV=1
UniRef50_W1QIW772.22%2885e-138GTPase NPA3 n=71 Tax=Fungi TaxID=4751 RepID=W1QIW7_OGAPD
GPN1_YEAST65.26%3082e-137GPN-loop GTPase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NPA3 PE=1 SV=1
A0A1E4TA66_9ASCO55.67%2913e-101Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_127271 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0389

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 425

Detailed signature matches

  1. Family IPR004130
    GPN-loop GTPase
    1. PF03029 (ATP_bind_1)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd00882 (Ras_like_G...)
  4. mobidb-lite (disord...)

Residue annotation

  1. G3 box cd00882
  2. Switch II region c...
  3. GTP/Mg2+ binding s...
  4. G4 box cd00882
  5. G5 box cd00882

Protein sequence

>MCA_01953_1
MSESANETNTQSPPPAIFCIGMAGSGKTTFMQRLNSHLHSKKKRPYVINLDPAVLKVPFGTNIDIRDSVNYKKVMENYNL
GPNGAIMTSLNLFATKIDQVLSIVEKRSIIKKSEDTKEKKEHEEKAATSTSSQKPVSHVIVDTPGQIECFIWSASGAIIT
DAFASSFPTIIAYIIDTPRSSSPTTFMSNMLYACSILYKTKLPMIVVFNKTDAKDAEFAKRWMTDFEEFQSAIRDDQYMN
EESGSGDSGYMSSLMNSMSLVLEEFYNHLDVVGVSAYTGEGFDDFLDAIDNKVEEYNRDYKAEREEILKQREVELQEKKA
KDLSRLLNDMGLGDDKKKGKGTAPIVADSISDVEEEEDEDDIDPDDYEDDLSSRFREGPKEIKSEFYGGRDSSLNDFVHD
NNETSDAGLQSQFAAALKAVGKDKI

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.