MCA_01945_1

Protein

Length

483 amino acids

Browser: contigA:5941939-5943391-

RNA-seq: read pairs 962, FPKM 24.6, percentile rank 47.3% (100% = highest expression)

Protein function

EGGNOG:	0QDAK		Major Facilitator Superfamily
SGD closest match:	S000005479	MCH4	Probable transporter MCH4
CGD closest match:	CAL0000190473	orf19.5720	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
MIA_00985_1	60.95%	443	1e-175	MIA_00985_1
A0A0J9X8E0_GEOCN	44.74%	447	1e-133	Similar to Saccharomyces cerevisiae YOL119C MCH4 Protein with similarity to mammalian monocarboxylate permeases OS=Geotrichum candidum GN=BN980_GECA05s01506g PE=4 SV=1
UniRef50_A0A0J9X8E0	44.74%	447	3e-130	Similar to Saccharomyces cerevisiae YOL119C MCH4 Protein with similarity to mammalian monocarboxylate permeases n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X8E0_GEOCN
A0A1E3PKI5_9ASCO	40.56%	429	2e-102	MFS general substrate transporter (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83425 PE=4 SV=1
A0A060TC07_BLAAD	31.25%	448	2e-66	ARAD1D36124p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D36124g PE=4 SV=1
A0A1E4TLK5_9ASCO	32.35%	439	5e-58	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1237 PE=4 SV=1
A0A167FRE1_9ASCO	31.52%	422	7e-56	Mch5p OS=Sugiyamaella lignohabitans GN=MCH5 PE=4 SV=1
Q6CCR5_YARLI	44.92%	256	3e-49	YALI0C07194p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C07194g PE=4 SV=1
MCH4_YEAST	25.55%	454	9e-34	Probable transporter MCH4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MCH4 PE=1 SV=1
A0A1D8PQ72_CANAL	26.33%	452	9e-32	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5720 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0099

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
61 - 472
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 483

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  82 - 405
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. SSF103473 (MFS gene...)
  
  61 - 472
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
2. cd06174 (MFS)
  
  79 - 469
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

195 - 205

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

471 - 483

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

139 - 144

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 78

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

406 - 416

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

258 - 294

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

353 - 358

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

285 - 477

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

75 - 274

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

226 - 236

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

165 - 169

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

380 - 384

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

314 - 332

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

441 - 451

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

107 - 117

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

358 - 380

TMHMM
TMhelix (TMhelix)

205 - 227

TMHMM
TMhelix (TMhelix)

80 - 102

TMHMM
TMhelix (TMhelix)

419 - 441

TMHMM
TMhelix (TMhelix)

451 - 473

TMHMM
TMhelix (TMhelix)

117 - 139

TMHMM
TMhelix (TMhelix)

146 - 168

TMHMM
TMhelix (TMhelix)

178 - 200

TMHMM
TMhelix (TMhelix)

385 - 407

TMHMM
TMhelix (TMhelix)

237 - 256

TMHMM
TMhelix (TMhelix)

297 - 319

TMHMM
TMhelix (TMhelix)

329 - 351

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

359 - 379

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

237 - 257

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

333 - 352

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

170 - 194

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

118 - 138

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

145 - 164

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

452 - 470

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

417 - 440

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

79 - 106

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

385 - 405

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

206 - 225

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

295 - 313

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
mobidb-lite (disord...)

1 - 61

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

92T

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

95V

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

96I

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

97T

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

99F

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

100G

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

123S

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

126Q

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

127L

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

130V

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

134G

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

135V

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

137T

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

138G

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

185M

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

186G

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

189F

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

190G

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

193L

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

194A

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

197S

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

208M

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

209C

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

212S

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

213S

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

219G

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

306F

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

309L

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

310Y

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

313F

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

314A

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

317Q

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

331T

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

335V

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

339N

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

342S

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

346R

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

393G

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

396S

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

397G

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

400G

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

404P

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

405F

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

408P

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

420R

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

421F

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

424C

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

425F

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

428L

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

429S

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

432T

putative substrate translocation pore
92T, 95V, 96I, 97T, 99F, 100G, 123S, 126Q, 127L, 130V, 134G, 135V, 137T, 138G, 185M, 186G, 189F, 190G, 193L, 194A, 197S, 208M, 209C, 212S, 213S, 219G, 306F, 309L, 310Y, 313F, 314A, 317Q, 331T, 335V, 339N, 342S, 346R, 393G, 396S, 397G, 400G, 404P, 405F, 408P, 420R, 421F, 424C, 425F, 428L, 429S, 432T
CDD
cd06174 (MFS)

Protein sequence

>MCA_01945_1
MTTHKPFAHLPGDSPIQESSSSAAENSTTDEIPEIYHETVNDQSLDEKLEKPSPVSEQENSFHKNHDVNYFPDGGIRAWL
CLLGGFLSVFTTWGVITSFGIFQSYYHTTLLNGHSSFQLGWISSLQLGCVFFGGVITGRPFDDGYFYHLLAAGSILIVVC
FMLLAECTQYYQVLLCQGIGMGLGMGALFGPCLACTSAYFKKYRGFAMCVCSSGGGVGGIIFPIIANNLLGKIGFPWTMR
VLGFIEVFLFAVMAIVMRDKLPFHVRQKYGRNSHQTSIFSLETWVDRTALKTPEYMFFVLGVSMCFFALYSPFAQIQSFS
SYTIGAENTVTRYIVAILNSASTVGRLAVYFIAKYTGALNMTVTYSLLASICCYTMFTIHQEPNLIVFTIFYGIISGVVG
TFPPFTVPHLTDDITKLGVRFGMCFFGLSLLTSFSVPVIGLTLGSDGHNFKAFSICCGSFFAAGCIFMLAGRISKAGIKL
VVI

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features