Protein
MCA_01925_1
Length
215 amino acids
Gene name: FAU1
Description: 5-formyltetrahydrofolate cyclo-ligase
Browser: contigA:5883492-5884200+
RNA-seq: read pairs 408, FPKM 23.3, percentile rank 45.6% (100% = highest expression)
Protein function
| Annotation: | FAU1 | 5-formyltetrahydrofolate cyclo-ligase | |
|---|---|---|---|
| KEGG: | K01934 | MTHFS | 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] |
| EGGNOG: | 0PQP3 | FAU1 | 5-formyltetrahydrofolate cyclo-ligase family |
| SGD closest match: | S000000985 | FAU1 | 5-formyltetrahydrofolate cyclo-ligase |
| CGD closest match: | CAL0000176281 | orf19.4523 | 5-formyltetrahydrofolate cyclo-ligase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02246_1 | 58.01% | 231 | 2e-89 | MIA_02246_1 |
| A0A0J9X7F5_GEOCN | 51.44% | 208 | 8e-71 | 5-formyltetrahydrofolate cyclo-ligase OS=Geotrichum candidum GN=BN980_GECA03s06566g PE=3 SV=1 |
| UniRef50_A0A0J9X7F5 | 51.44% | 208 | 2e-67 | 5-formyltetrahydrofolate cyclo-ligase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X7F5_GEOCN |
| A0A1E3PSA0_9ASCO | 49.29% | 211 | 2e-68 | 5-formyltetrahydrofolate cyclo-ligase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_54682 PE=3 SV=1 |
| A0A060T4A3_BLAAD | 47.83% | 161 | 4e-51 | ARAD1C39864p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C39864g PE=4 SV=1 |
| Q6CAN2_YARLI | 37.38% | 214 | 4e-42 | 5-formyltetrahydrofolate cyclo-ligase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D01309g PE=3 SV=1 |
| FTHC_YEAST | 34.76% | 210 | 5e-35 | 5-formyltetrahydrofolate cyclo-ligase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FAU1 PE=1 SV=1 |
| A0A167FS62_9ASCO | 50.86% | 116 | 2e-35 | 5-formyltetrahydrofolate cyclo-ligase OS=Sugiyamaella lignohabitans GN=FAU1 PE=4 SV=1 |
| Q59TA8_CANAL | 36.70% | 218 | 1e-33 | 5-formyltetrahydrofolate cyclo-ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4523 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.7014
Protein family membership
- 5-formyltetrahydrofolate cyclo-ligase (IPR002698)
Domains and repeats
None predicted.
Detailed signature matches
-
-
-
PIRSF006806 (5_FTHF)
-
PF01812 (5-FTHF_cyc...)
-
no IPR
Unintegrated signatures
-
-
SSF100950 (NagB/Rpi...)
Protein sequence
>MCA_01925_1 MTSLAKKELRKLIKQNLHSATDISEQSKNVTKILKDLPAFQKALSVACYLHMDQHEIETDLIIQQIFQSGKSLFLPRLVD LPVSQHGVLFKNHKKEMKMLLVESQQEIDSYEPQGPYKLREPPETKKSCFDIDGLDLIIVPGLGFTSKCHRIGHGKGFYD TFIKKCNAWSAEHSRPRPYLVGIGAKEQLVEHIPQEEHDHPLDAVIINDKLFVNE
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.