MCA_01913_1

Protein

Length

511 amino acids

RNA-seq: read pairs 34, FPKM 0.8, percentile rank 8.5% (100% = highest expression)

Protein function

EGGNOG:	0PJ3T	FG06336.1	mono-carboxylate
SGD closest match:	S000005479	MCH4	Probable transporter MCH4
CGD closest match:	CAL0000180528	orf19.2751	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
A0A0J9XH20_GEOCN	40.92%	501	4e-126	Similar to Saccharomyces cerevisiae YOL119C MCH4 Protein with similarity to mammalian monocarboxylate permeases OS=Geotrichum candidum GN=BN980_GECA17s00593g PE=4 SV=1
UniRef50_A0A0J9XH20	40.92%	501	9e-123	Similar to Saccharomyces cerevisiae YOL119C MCH4 Protein with similarity to mammalian monocarboxylate permeases n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XH20_GEOCN
MIA_03436_1	39.41%	505	5e-125	MIA_03436_1
A0A060TFW4_BLAAD	51.44%	208	3e-69	ARAD1D17842p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D17842g PE=4 SV=1
Q6CEH9_YARLI	45.75%	212	6e-58	YALI0B15488p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B15488g PE=4 SV=1
A0A1E3PKI5_9ASCO	27.87%	445	1e-42	MFS general substrate transporter (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83425 PE=4 SV=1
A0A167FRE1_9ASCO	40.48%	210	2e-34	Mch5p OS=Sugiyamaella lignohabitans GN=MCH5 PE=4 SV=1
A0A1D8PLJ9_CANAL	25.39%	449	1e-26	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2751 PE=4 SV=1
A0A1E4TLK5_9ASCO	31.63%	215	6e-24	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1237 PE=4 SV=1
MCH4_YEAST	30.77%	195	2e-19	Probable transporter MCH4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MCH4 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0397

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
24 - 511
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 511

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  41 - 344
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  314 - 511
  
  PROSITE profiles
  PS50850 (MFS)
2. SSF103473 (MFS gene...)
  
  301 - 500
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
  
  24 - 232
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
3. cd06174 (MFS)
  
  36 - 500
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

434 - 444

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

98 - 103

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

150 - 160

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

377 - 382

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

215 - 307

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

500 - 511

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

289 - 507

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

3 - 249

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

1 - 73

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

403 - 407

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

124 - 128

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

335 - 353

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

470 - 480

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

182 - 192

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

383 - 405

TMHMM
TMhelix (TMhelix)

482 - 504

TMHMM
TMhelix (TMhelix)

410 - 432

TMHMM
TMhelix (TMhelix)

354 - 376

TMHMM
TMhelix (TMhelix)

196 - 218

TMHMM
TMhelix (TMhelix)

100 - 122

TMHMM
TMhelix (TMhelix)

162 - 181

TMHMM
TMhelix (TMhelix)

312 - 334

TMHMM
TMhelix (TMhelix)

127 - 149

TMHMM
TMhelix (TMhelix)

445 - 467

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

161 - 181

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

129 - 149

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

74 - 97

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

408 - 433

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

193 - 214

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

481 - 499

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

308 - 334

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

445 - 469

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

104 - 123

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

383 - 402

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

354 - 376

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
mobidb-lite (disord...)

269 - 292

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 28

MobiDB Lite
mobidb-lite (disorder_prediction)

222 - 245

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

50Y

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

53V

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

54N

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

55T

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

57G

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

58Q

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

79G

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

82Q

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

83P

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

86I

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

90A

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

91V

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

93A

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

94V

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

141M

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

142G

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

145C

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

146F

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

149F

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

150A

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

153Q

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

164S

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

165G

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

168A

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

169S

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

175G

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

331F

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

334Q

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

335Y

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

338L

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

339F

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

342P

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

355Y

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

359L

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

363N

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

366S

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

370R

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

418G

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

421S

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

422G

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

425I

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

429A

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

430S

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

433G

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

444R

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

445L

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

448M

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

449F

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

452D

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

453S

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

456A

putative substrate translocation pore
50Y, 53V, 54N, 55T, 57G, 58Q, 79G, 82Q, 83P, 86I, 90A, 91V, 93A, 94V, 141M, 142G, 145C, 146F, 149F, 150A, 153Q, 164S, 165G, 168A, 169S, 175G, 331F, 334Q, 335Y, 338L, 339F, 342P, 355Y, 359L, 363N, 366S, 370R, 418G, 421S, 422G, 425I, 429A, 430S, 433G, 444R, 445L, 448M, 449F, 452D, 453S, 456A
CDD
cd06174 (MFS)

Protein sequence

>MCA_01913_1
MTETNNKSEKEKKETKNRPGIGERDTEEFPEGGRGWLVVAGSFVALAQSYGIVNTFGQYQIEYETIYPTTKSEIISLVGS
LQPCIINLTAVAAVPLMKKFGPQVTVLISMVLVTFGFMMLSLSKAIWQVFLTQGILIGFGMGLCCFAGFAVPQQWFKKKR
ALASGIVASGSSLGGMVWPIAVSHLSKSVGMPWTNRIIGFIYIPLLTFAAFSMTPRILDSEKERKQQDLEKTAAAGDHGS
HHHQQNNNDLIADELAEELNLEQGNEENGELGLMNKHHSSPSSSSSPAITTTDNKPTKKYLWIFHKHFLVDWTVINDLSF
CIFLFSTFMSFLGQYPPLFYLPTYCRRIGASPSVYNYILTIANAASLFGRIVPGYIGDHIGRLNALIPFILFSGISILVF
WLPTESVALTIVFAVMYGAASGSVISLYASVVGQLFGIKGLPSRLTLMFVVDSVPALIGPVIAGTFIPTSGYEGTEGFSK
LMIFSAVSFLVGGVALVYLRLSISRKLFVFV

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features