Protein

MCA_01900_1

Length
963 amino acids


Gene name: DCP2

Description: m7GpppN-mRNA hydrolase

Browser: contigA:5825082-5828061+

RNA-seq: read pairs 2588, FPKM 33.2, percentile rank 55.4% (100% = highest expression)

Protein function

Annotation:DCP2m7GpppN-mRNA hydrolase
KEGG:K12613DCP2 mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
EGGNOG:0PJA5DCP2decapping enzyme
SGD closest match:S000005062DCP2m7GpppN-mRNA hydrolase
CGD closest match:CAL0000180572DCP2Decapping enzyme complex catalytic subunit

Protein alignments

%idAln lengthE-value
MIA_02222_167.96%3873e-163MIA_02222_1
A0A0J9XF99_GEOCN61.43%3502e-136Similar to Saccharomyces cerevisiae YNL118C DCP2 Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex OS=Geotrichum candidum GN=BN980_GECA14s01055g PE=4 SV=1
UniRef50_A0A0J9XF9961.43%3504e-133Similar to Saccharomyces cerevisiae YNL118C DCP2 Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XF99_GEOCN
A0A060SW71_BLAAD54.10%3665e-113ARAD1A02508p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A02508g PE=4 SV=1
A0A1E3PQ12_9ASCO48.04%3834e-99Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49757 PE=4 SV=1
Q6CC24_YARLI51.42%2472e-79YALI0C13310p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C13310g PE=4 SV=1
A0A1E4TJ00_9ASCO39.75%3171e-62Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30068 PE=4 SV=1
A0A1D8PTQ2_CANAL43.72%2472e-58Decapping enzyme complex catalytic subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DCP2 PE=4 SV=1
DCP2_YEAST43.48%2307e-58m7GpppN-mRNA hydrolase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DCP2 PE=1 SV=1
A0A167FPV8_9ASCO64.29%981e-42Decapping enzyme complex catalytic subunit DCP1 OS=Sugiyamaella lignohabitans GN=DCP2 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2253

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 963

Detailed signature matches

    1. SM01125 (DCP2_2)
    2. PF05026 (DCP2)
    3. SSF140586 (Dcp2 dom...)
    1. SSF55811 (Nudix)
    1. PS51462 (NUDIX)
    2. PF00293 (NUDIX)
    1. PS00893 (NUDIX_BOX)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd03672 (Dcp2p)
  2. mobidb-lite (disord...)

Residue annotation

  1. nudix motif cd03672
  2. putative metal bin...
  3. putative catalytic...

Protein sequence

>MCA_01900_1
MSIPSTFSYSKEPLINALQDLAVRFILNDPEEDVEKPERLCFQLEEAQWFYEDFVRVENPTFPSLKLKAFSRHLFSVCPV
LNKFISGSELTKAIGIFQDYKSVIPVRGAIILNKKMTKVLMVKGWKSNATWGFPKGKINKDEPDDLCAIREVYEEIGFDI
GPYLCKTDYIDITIRRKNFKLFIIRGVPGSTKFCPQTRKEISKIEWHDVKTLPAFSSEYSSTNSNQYFLVAPFMHGLAKY
IAKKRGLPTALSSTEAAALTHLLGGSTSSNETKFIDKDAAASELLNMLKSSKNFNESGAQDKDEQVVRDLFKNSETNEAV
KPDIDSAQELLSLLKTEIDRTNEEATLEAVTEGSTIAQNAQQASTNNSEAQPQMAPQQLYPPNMPYGMPYPNMPYPQMMP
MNMMNGGVPMFYPPMYDYRLGMAMPPQQMGQFNQQQPVPFPAPQEVPPVQPSPRPSSVQPAEPQMSFSGEPPKKEIPLPP
PPKFPTSQPTPALMALLSKSRTKRQVASSSSSNFEKTPSTLPPVPTGPSSSSKALLSLLHMPGSESKPPTPSEVPKEPEI
KPNEQQPSSIADLFMSGAVHRQQKLDEQKNDTDNTQFNQMKPDIESSKSLLSMIKGNNSIENNAEQEHTNSNNVNKPNDF
KSQELLSLIKSSVPDASQSSPNPQISVNENSNLATDLQNQLFVSDPASNANQTISLKDQLFGNFTTDSAANMHVQNNTEM
SKETSIKDQIFGTLMSTPANENVASSEPSKEKSIKHLLFGGGAPVSMSESITTENPPKMLTLSELESQQRNNLSANIQNQ
ATTVESNPTFSINSGNNYDHNNPANGNGTPQTQMSTSLKDFLFGTQPTDTSMNRISQSNNINTNNNPNIVLKSQSQTQTT
IANQPPLNLGPAGSQQSGPTNSAGNELLSLLRSPAMENGQSEKTVPAPVSNTSASGSPSAPENDQNAMLLDFLRDYGSNT
LRK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003723 RNA binding
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding

Cellular Component

None predicted.