Protein

MCA_01883_1

Length
403 amino acids

Browser: contigA:5771118-5772408-

RNA-seq: read pairs 7828, FPKM 239.4, percentile rank 90.0% (100% = highest expression)

Protein function

KEGG:K00966GMPP mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
EGGNOG:0PIF7PSA2GDP-mannose pyrophosphorylase
SGD closest match:S000002213PSA1Mannose-1-phosphate guanyltransferase
CGD closest match:CAL0000185249PSA2Psa2p

Protein alignments

%idAln lengthE-value
A0A0J9X6A9_GEOCN76.70%4120.0Similar to Saccharomyces cerevisiae YDL055C PSA1 GDP-mannose pyrophosphorylase (Mannose-1-phosphate guanyltransferase) OS=Geotrichum candidum GN=BN980_GECA03s05334g PE=4 SV=1
UniRef50_A0A0J9X6A976.70%4120.0Similar to Saccharomyces cerevisiae YDL055C PSA1 GDP-mannose pyrophosphorylase (Mannose-1-phosphate guanyltransferase) n=4 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X6A9_GEOCN
MIA_04315_177.17%4030.0MIA_04315_1
A0A060TA23_BLAAD68.61%4110.0ARAD1C41624p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C41624g PE=4 SV=1
Q6C5U4_YARLI69.17%4120.0YALI0E15125p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E15125g PE=4 SV=1
A0A161HH23_9ASCO65.22%4140.0Mannose-1-phosphate guanylyltransferase OS=Sugiyamaella lignohabitans GN=PSA1 PE=4 SV=1
A0A1E3PLB1_9ASCO57.51%4264e-161Nucleotide-diphospho-sugar transferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82116 PE=4 SV=1
A0A1E4TID7_9ASCO56.52%4149e-160Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_55378 PE=4 SV=1
Q5AL34_CANAL39.01%4642e-88Psa2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PSA2 PE=4 SV=1
MPG1_YEAST31.92%4013e-59Mannose-1-phosphate guanyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PSA1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8280
Predicted cleavage: 29

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Repeat
1 50 100 150 200 250 300 350 403

Detailed signature matches

  1. Domain IPR029044
    Nucleotide-diphospho-sugar transferases
    1. G3DSA:3.90.55...
    2. SSF53448 (Nucleotid...)
  2. Domain IPR005835
    Nucleotidyl transferase domain
    1. PF00483 (NTP_transf...)
  3. Repeat IPR001451
    Hexapeptide repeat
    1. PF00132 (Hexapep)
  4. SITE IPR018357
    Hexapeptide transferase, conserved site
    1. PS00101 (HEXAPEP_TR...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.160.1...
  2. cd06428 (M1P_guanyl...)

Residue annotation

  1. putative substrate...
  2. metal binding site...

Protein sequence

>MCA_01883_1
MASKALILVGGGTRGTRFRPLSLDIPKVLFPVAGKPIVSHAIDKIVTIPTIKEILLIGFYDDSVFRDYINEAHKQYPGIS
IKYLREYKAMGTAGGLYHFRDVILKGNPKKFYVIHADVCCSFPLKEIDELFEEKNAKAVILGTKVSKEEATNYGTIVADP
TSKKVIHYVEKPESQISNLINAGVYLFDQSLFDTIAEAKAAHDEAKEPSFNEDDDEEVLRLEQDILVRLPASDKFFVYET
KDFWLQIKNAGSAVPANALYLQQLFQTNPNAPGLAQPSSTIVPPVYIDPSAVVDETAKLGPNVSIGPGAKIGKGARINDS
IILQDVEVKHDAIVLHSIVSIGSKIGAWARVEGCPSNPSPSSCKDGITILSSNVSVANEVHIQNSLVLPHKEIKSDVKNE
VIM

GO term prediction

Biological Process

GO:0009058 biosynthetic process

Molecular Function

GO:0016740 transferase activity
GO:0016779 nucleotidyltransferase activity

Cellular Component

None predicted.