Protein

MCA_01875_1

Length
1,111 amino acids

Gene name: ISW2B

Description: chromatin-remodeling complex ATPase ISW2

Browser: contigA:5744518-5748205+

RNA-seq: read pairs 665, FPKM 7.4, percentile rank 21.2% (100% = highest expression)

Protein function

Annotation:ISW2Bchromatin-remodeling complex ATPase ISW2
KEGG:K11654SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]
EGGNOG:0PG55FG10269.1complex ATPase
SGD closest match:S000005831ISW2ISWI chromatin-remodeling complex ATPase ISW2
CGD closest match:CAL0000192526ISW2ISWI chromatin-remodeling complex ATPase ISW2

Protein alignments

%idAln lengthE-value
MIA_02500_178.30%10460.0MIA_02500_1
A0A0J9XBV8_GEOCN74.63%10800.0Chromatin-remodeling complex ATPase OS=Geotrichum candidum GN=BN980_GECA08s02947g PE=3 SV=1
A0A060SXP6_BLAAD67.25%10260.0Chromatin-remodeling complex ATPase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A10956g PE=3 SV=1
A0A1E3PRM6_9ASCO63.95%10790.0Chromatin-remodeling complex ATPase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_20910 PE=3 SV=1
UniRef50_A0A1E3PRM663.95%10790.0Chromatin-remodeling complex ATPase n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PRM6_9ASCO
A0A167EFB2_9ASCO66.07%9550.0Chromatin-remodeling complex ATPase OS=Sugiyamaella lignohabitans GN=ISW2 PE=3 SV=1
A0A1E4TK67_9ASCO66.70%9520.0Chromatin-remodeling complex ATPase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_748 PE=3 SV=1
Q6CA54_YARLI64.34%9590.0Chromatin-remodeling complex ATPase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D05775g PE=3 SV=1
ISW2_CANAL60.84%9960.0ISWI chromatin-remodeling complex ATPase ISW2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ISW2 PE=2 SV=1
ISW2_YEAST60.22%10080.0ISWI chromatin-remodeling complex ATPase ISW2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ISW2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0528

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 200 400 600 800 1000 1111

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  3. Domain IPR000330
    SNF2-related, N-terminal domain
    1. PF00176 (SNF2_N)
  4. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
  5. Domain IPR015194
    ISWI, HAND domain
    1. SSF101224 (HAND dom...)
    2. PF09110 (HAND)
  6. Domain IPR009057
    Homeobox domain-like
    1. SSF46689 (Homeodoma...)
  7. Domain IPR001005
    SANT/Myb domain
    1. SM00717 (sant)
  8. Domain IPR015195
    SLIDE domain
    1. PF09111 (SLIDE)
  9. Domain IPR017884
    SANT domain
    1. PS51293 (SANT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.10.60
  3. G3DSA:1.20.5....
  4. G3DSA:3.40.50...
  5. G3DSA:3.40.50...
  6. cd00046 (DEXDc)
  7. cd00079 (HELICc)
  8. cd00167 (SANT)
  9. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. putative Mg++ bind...
  3. nucleotide binding...
  4. ATP-binding site c...
  5. DNA binding site c...

Protein sequence

>MCA_01875_1
MPSADISSQSKQESLSDSKIIDISDSNSPQQTPTEDDKKENEQRQPLVAKPKDPDPLSPSEIQARSKYYLVENIPAKAST
KKNDMIKRFTYLLGLTDLFRHFIDIRAKNDPETKKILRDIDRSAKEKATVSRNSNRGSNARRRKTEKEEDAELLIEEDEE
EEEHITVFTESPSYINGTLREYQVQGLNWLVSLHEHSISGILADEMGLGKTLQTISFIGYLRFIKDIKGPHLVVVPKSTL
DNWAREFNKWIPEINVVVIQGDKTQRAELFANRLLSFNFDVCITSYEVVIREKAQLKKIAWQYIIVDEAHRIKNEDSALS
QIIRLFYSRNRLLITGTPLQNNLHELWALLNFILPDVFTDSEAFDQWFGGDDEEQDQDTIVQQLHKVLKPFLLRRVKADV
EKSLLPKKEINLYVGMAEMQVKWYQKLLEKDIDAVNGAVGKREGKTRLLNIVMQLRKCCNHPYLFEGAEPGPPYTTDEHL
IYNCGKMVILDKLLKRLKTQGSRVLIFSQMSRLLDILEDYCMFREYEYCRIDGSTDHEERVQAIDDFNRPGSDKFVFLLT
TRAGGLGINLTTADIVILYDSDWNPQADLQAMDRAHRIGQTKQVYVFRFITENAIEEKVLERAAQKLRLDQLVIQQGRSQ
QNANKNTAASKDDLVRMIQYGAENIFNSSGGTMKDDDIDSILRHGEERTKELNAKYSKLGLDDLQKFTSEGSAYEWNGED
FTKKNKLGGGHVWINPAKRERKGLTYSIDDYYKDILHQSKEKSQARTPRPPKQINIQDFQFFPKRLKELQDKEMAYYRKQ
IGFKFSSADMTNLEEGETKESKRKKENQIIENAVPLTAEEIEEKEEIIRNGFSNWSKRDLTNFIHQAAKYGRDNYTQIAQ
DMDGKTPKEVEAYSKVFWEKYKEIDGWERYLAQIEAGEERLKKLFHQQKLLRQKVGQYNVPQCEMVITYPANNSKKTYSV
DEDRFILIMADKYGLASDNIWEKVQEEIKKSPLFRFDWFFLSRTTVELSRRCATLLLAVTREIEGPNAMKRKSGPKKGSS
KASTTVNSEAPSAPDTPGPTAADSAPEDGDSSSEQPPTKKQRKSRLSEVKDEATITPSKSPKGRKPRQGSA

GO term prediction

Biological Process

GO:0006338 chromatin remodeling
GO:0043044 ATP-dependent chromatin remodeling

Molecular Function

GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0031491 nucleosome binding

Cellular Component

GO:0005634 nucleus