Protein

MCA_01872_1

Length
392 amino acids

Gene name: CMK1A

Description: Calmodulin-dependent protein kinase 1

Browser: contigA:5738743-5739922+

RNA-seq: read pairs 4688, FPKM 147.4, percentile rank 84.6% (100% = highest expression)

Protein function

Annotation:CMK1ACalmodulin-dependent protein kinase 1
KEGG:K08794CAMK1 calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
EGGNOG:0PJ6NFG06878.1calcium calmodulin-dependent protein kinase
SGD closest match:S000001910CMK1Calcium/calmodulin-dependent protein kinase I
CGD closest match:CAL0000178532CMK2Calmodulin-dependent protein kinase

Protein alignments

%idAln lengthE-value
MIA_02454_170.44%3890.0MIA_02454_1
A0A0J9X923_GEOCN64.63%3930.0Similar to Saccharomyces cerevisiae YOL016C CMK2 Calmodulin-dependent protein kinase OS=Geotrichum candidum GN=BN980_GECA05s04927g PE=3 SV=1
A0A060TB87_BLAAD57.51%3863e-160ARAD1B13838p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B13838g PE=3 SV=1
A0A1E3PGZ2_9ASCO56.57%3963e-152Pkinase-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_26349 PE=4 SV=1
A0A167CX64_9ASCO60.48%3341e-149Calmodulin-dependent protein kinase CMK2 OS=Sugiyamaella lignohabitans GN=CMK2 PE=3 SV=1
Q6C4D8_YARLI54.02%3983e-146YALI0E27632p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E27632g PE=3 SV=1
UniRef50_Q0077158.86%3334e-133Calcium/calmodulin-dependent protein kinase cmkA n=132 Tax=Fungi TaxID=4751 RepID=KCC1A_EMENI
Q59XV1_CANAL54.98%3312e-133Calmodulin-dependent protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CMK2 PE=3 SV=1
KCC1_YEAST52.84%3353e-119Calcium/calmodulin-dependent protein kinase I OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CMK1 PE=1 SV=2
A0A1E4T9Q5_9ASCO53.39%3397e-120Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17827 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7077

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 392

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:3.30.20...
  3. PIRSF000654 (ILK)
  4. cd05117 (STKc_CAMK)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd05117
  3. polypeptide substr...
  4. activation loop (A...

Protein sequence

>MCA_01872_1
MAFQSILGRVSQPSSYKQKSEYEFGKTLGAGTFGEVKQAIHIPTKEVVAIKIILKKGLQGNDQMVKDELAMLQALHHPHI
VHFRTWFESREKYYIVTELATGGELFDRICEMGKFTEKDAVSTIRQILDPIIYLHDRDIVHRDLKPENLLYRTEAKDSEL
VLADFGIAKKLDSPNQKLTTRAGSFGYAAPEVLMGTGHGKPCDIWSLGVITYTILSGYSPFRSETIDGFIDEVSDPFFLV
FHEKYWKSISQEAKQFIRGMLTIDPEKRPDAHALMKDPWIAGDVANSTTDLLPNIRPQFNARQQLRRGIEAIRLRNKLAS
IVDNVDSDDEGDSESIASSNSNTNSLSPVSSGSATTSGTLSFQAIVDAAIRNKDIIKAHDEAEKLKTKDSSS

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.