Protein

MCA_01856_1

Length
436 amino acids

Gene name: FBP26

Description: Fructose-2,6-bisphosphatase

Browser: contigA:5702122-5703813-

RNA-seq: read pairs 1740, FPKM 49.2, percentile rank 65.0% (100% = highest expression)

Protein function

Annotation:FBP26Fructose-2,6-bisphosphatase
KEGG:K19029PFKFB2 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 2 [EC:2.7.1.105 3.1.3.46]
EGGNOG:0PIZYFBP26Fructose-2,6-bisphosphatase
SGD closest match:S000003691FBP26Fructose-2,6-bisphosphatase
CGD closest match:CAL0000186425CAALFM_CR08550WAFructose-2,6-bisphosphatase

Protein alignments

%idAln lengthE-value
MIA_02553_188.63%4310.0MIA_02553_1
A0A0J9X949_GEOCN85.21%4260.0Similar to Saccharomyces cerevisiae YJL155C FBP26 Fructose-2,6-bisphosphatase OS=Geotrichum candidum GN=BN980_GECA05s06896g PE=4 SV=1
A0A060TE12_BLAAD75.23%4320.0ARAD1D11924p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D11924g PE=4 SV=1
UniRef50_A0A060TE1275.23%4320.0ARAD1D11924p n=64 Tax=cellular organisms TaxID=131567 RepID=A0A060TE12_BLAAD
A0A1E4TJH3_9ASCO71.40%4300.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22960 PE=4 SV=1
A0A167BYZ0_9ASCO80.00%3700.0Fbp26p OS=Sugiyamaella lignohabitans GN=FBP26 PE=4 SV=1
Q6C5J2_YARLI69.44%4320.0YALI0E17633p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E17633g PE=4 SV=1
A0A1E3PQF2_9ASCO63.79%4280.0Bifunctional 6-phosphofructo-2-kinase/fructose-2,6-bisphosphate 2-phosphatase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82084 PE=4 SV=1
F26_YEAST61.84%4350.0Fructose-2,6-bisphosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FBP26 PE=1 SV=2
Q5A340_CANAL67.06%2528e-114Fructose-2,6-bisphosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR08550WA PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8931
Predicted cleavage: 46

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 436

Detailed signature matches

  1. Family IPR029033
    Histidine phosphatase superfamily
    1. G3DSA:3.40.50...
    2. SSF53254 (Phosphogl...)
  2. Family IPR013078
    Histidine phosphatase superfamily, clade-1
    1. PF00300 (His_Phos_1)
    2. SM00855 (PGAM_5)
    3. cd07067 (HP_PGM_like)
  3. Family IPR003094
    Fructose-2,6-bisphosphatase
    1. PR00991 (6PFRUCTKNASE)
  4. Domain IPR013079
    6-phosphofructo-2-kinase
    1. PF01591 (6PF2K)
  5. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  6. SITE IPR001345
    Phosphoglycerate/bisphosphoglycerate mutase, active site
    1. PS00175 (PG_MUTASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. PIRSF000709 (6PFK_f...)
  4. mobidb-lite (disord...)

Residue annotation

  1. catalytic core cd0...

Protein sequence

>MCA_01856_1
MVTGYIISQADKTRLCVVMVGLPARGKSFMAQKIVRYLSWLSIKAKSFNVGSYRRLHEAHPSADFFDVHNTEGEKLRRQA
AELAVKDMMEWFETEDGVVAILDATNSTKQRRTWIRGLLAKHSIEPFFVESWCDDKDLIWNNIMDVKTTSPDYVGQDPEE
AAKDFMARIKKYEEVYETLDDTEIDYCYVKIINVSTQVIINKIQSYLQSRIVYYVMNLHIKRRCIWLSRHGESEYNLTGK
LGGDANLSPRGEMYARKLPELVKAAVGDRPLTVWTSTLRRTQQTARFLPYPKLAWKALDELDAGVCDGMTYEEIEQKYPE
DFKARDADKYEYRYRGGESYRDVVTRLEPIIMELERQENIMIVTHQAVLRCIYAYFMNVPQDRSPWMVVPLHTLIQLEPR
PYSTNETRVPANIPSVSTFREKGTTSKHDATVSTNH

GO term prediction

Biological Process

GO:0006000 fructose metabolic process
GO:0006003 fructose 2,6-bisphosphate metabolic process
GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0003873 6-phosphofructo-2-kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.