Protein

MCA_01833_1

Length
295 amino acids

Browser: contigA:5612762-5613834+

RNA-seq: read pairs 1543, FPKM 64.4, percentile rank 70.7% (100% = highest expression)

Protein function

KEGG:K12584DCPS m7GpppX diphosphatase [EC:3.6.1.59]
EGGNOG:0PFAXFG09810.1mRNA decapping
SGD closest match:S000005699DCS2Inactive diphosphatase DCS2
CGD closest match:CAL0000181791orf19.69015'-(N(7)-methyl 5'-triphosphoguanosine)-(mRNA) diphosphatase

Protein alignments

%idAln lengthE-value
MIA_03627_163.33%3001e-139MIA_03627_1
A0A060T1S5_BLAAD55.28%2842e-117ARAD1C23232p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C23232g PE=4 SV=1
A0A0J9X5X9_GEOCN54.76%2946e-114Similar to Saccharomyces cerevisiae YLR270W DCS1 Non-essential hydrolase involved in mRNA decapping OS=Geotrichum candidum GN=BN980_GECA03s04168g PE=4 SV=1
UniRef50_A0A0J9X5X954.76%2941e-110Similar to Saccharomyces cerevisiae YLR270W DCS1 Non-essential hydrolase involved in mRNA decapping n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X5X9_GEOCN
Q6BZT0_YARLI44.55%3033e-86YALI0F31141p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F31141g PE=4 SV=1
A0A1D8PQS6_CANAL45.14%2888e-845'-(N(7)-methyl 5'-triphosphoguanosine)-(mRNA) diphosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6901 PE=4 SV=1
DCS2_YEAST40.43%3241e-76Inactive diphosphatase DCS2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DCS2 PE=1 SV=3
A0A1E3PQ60_9ASCO51.32%1894e-61HIT-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81667 PE=4 SV=1
A0A1E4TBL1_9ASCO35.34%2833e-48Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58177 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6687

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 295

Detailed signature matches

  1. Family IPR008594
    Scavenger mRNA decapping enzyme DcpS/DCS2
    1. PIRSF028973 (DcpS)
    2. PF05652 (DcpS)
  2. Domain IPR011145
    Scavenger mRNA decapping enzyme, N-terminal
    1. SSF102860 (mRNA dec...)
  3. Domain IPR011146
    HIT-like domain
    1. SSF54197 (HIT-like)
    2. G3DSA:3.30.42...
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.22...
  2. PF11969 (DcpS_C)

Protein sequence

>MCA_01833_1
MSLIERFVFEKVIDNDIDTKKVTLLGTIEGQLAILSIEKLPFDASKEFSDYKSLGLDQIKSLDRNDIYSWNLATMIQDLE
TSPSAKVDLIYPATETHLKKYEKAKKRYIVETPELYRKYVVPYISTMKGDRIKWVRQILHEGVEADRVLVRVDDEKNGFV
LLPNLKWDRKNLETLYLVAIVIRDDISSVRDFTEEHIPMLEFIRKTILDTVYEKYGLTSSELKIFIHYQPSYYHFHIHVA
HVQLERHDFGTSLFLDWVIDQLKLLGPKGFSESTFNYLLSERHDLWTNGFSKELK

GO term prediction

Biological Process

GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA

Molecular Function

GO:0003824 catalytic activity
GO:0016787 hydrolase activity

Cellular Component

None predicted.