Protein

MCA_01798_1

Length
437 amino acids


Gene name: RPT1

Description: 26S proteasome regulatory subunit 7 homolog; ATPase of the 19S regulatory particle of the 26S proteasome

Browser: contigA:5483941-5485339-

RNA-seq: read pairs 6814, FPKM 192.2, percentile rank 87.6% (100% = highest expression)

Protein function

Annotation:RPT126S proteasome regulatory subunit 7 homolog; ATPase of the 19S regulatory particle of the 26S proteasome
KEGG:K03061PSMC2 26S proteasome regulatory subunit T1
EGGNOG:0PG2PRPT126S protease regulatory subunit 7
SGD closest match:S000001628RPT126S proteasome regulatory subunit 7 homolog
CGD closest match:CAL0000180078RPT1Proteasome regulatory particle base subunit

Protein alignments

%idAln lengthE-value
MIA_02388_194.97%4370.0MIA_02388_1
A0A0J9XHK4_GEOCN92.92%4380.0Similar to Saccharomyces cerevisiae YKL145W RPT1 One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates OS=Geotrichum candidum GN=BN980_GECA15s01099g PE=3 SV=1
A0A161HKU4_9ASCO89.27%4380.0Proteasome regulatory particle base subunit RPT1 OS=Sugiyamaella lignohabitans GN=RPT1 PE=3 SV=1
A0A060TBW7_BLAAD89.24%4370.0ARAD1D35244p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D35244g PE=3 SV=1
Q6C9G4_YARLI89.24%4370.0YALI0D11418p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D11418g PE=3 SV=1
A0A1E3PNX6_9ASCO87.00%4460.0Protease subunit component OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45992 PE=3 SV=1
A0A1E4TIJ2_9ASCO87.19%4370.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_131 PE=3 SV=1
UniRef50_A3GFY885.20%4460.0Protease subunit component n=64 Tax=Eukaryota TaxID=2759 RepID=A3GFY8_PICST
Q5A2A0_CANAL83.18%4460.0Proteasome regulatory particle base subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RPT1 PE=3 SV=1
PRS7_YEAST79.23%4670.026S proteasome regulatory subunit 7 homolog OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPT1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0010

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 437

Detailed signature matches

    1. SSF52540 (P-loop co...)
    1. SM00382 (AAA_5)
    1. PF00004 (AAA)
    1. PS00674 (AAA)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00009 (AAA)
  2. mobidb-lite (disord...)

Residue annotation

  1. Walker A motif cd0...
  2. ATP binding site c...
  3. Walker B motif cd0...
  4. arginine finger cd...

Protein sequence

>MCA_01798_1
MPPKADWEKYKAPVEDDEAEQKDIIPLSEGDIQVLKSYGAAPYGTALKEIEKDIKDIQTRINEKIGIKESDTGLAPPHQW
DLAADKQNMGQEQPLQVARCTKIIQAEDDSEKSKYVINVKQLAKFVVSLGDRVSPTDIEEGMRVGVDRNKYQIMLPLPPR
IDPSVTMMTVEEKPDVTYSDIGGCKEQIEKLREVVELPLLSPERFVSLGIDPPKGILLYGPPGTGKTLCARAVANRTDAT
FIRVIGSELVQKYVGEGARMVRDLFEMARSKKATIIFFDEVDAIGGARFDDGAGGDNEVQRTMLELITQLDGFDSRGNIK
VMFATNRPNTLDPALLRPGRIDRKVEFSLPDVEGRANILRIHAKSMSVDRDIRWELISRLCPNSTGAELRSVCTEAGMFA
IRARRKVASEKDFLAAVEKVIKGNLKFSSTSRYMQYN

GO term prediction

Biological Process

GO:0030163 protein catabolic process

Molecular Function

GO:0005524 ATP binding
GO:0016787 hydrolase activity

Cellular Component

GO:0005737 cytoplasm