Protein

MCA_01768_1

Length
284 amino acids

Gene name: RIB7

Description: 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase

Browser: contigA:5413323-5414178-

RNA-seq: read pairs 466, FPKM 20.2, percentile rank 41.7% (100% = highest expression)

Protein function

Annotation:RIB72,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
KEGG:K14654RIB7 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302]
EGGNOG:0PMP3RIB7riboflavin biosynthesis protein
SGD closest match:S000000357RIB72,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
CGD closest match:CAL0000179348orf19.63412,5-diamino-6-(Ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase

Protein alignments

%idAln lengthE-value
MIA_00709_159.41%3034e-123MIA_00709_1
A0A0J9X5H7_GEOCN47.37%2853e-81Similar to Saccharomyces cerevisiae YBR153W RIB7 Diaminohydroxyphoshoribosylaminopyrimidine deaminase,catalyzes the second step of the riboflavin biosynthesis pathway OS=Geotrichum candidum GN=BN980_GECA03s01066g PE=4 SV=1
A0A167FQQ7_9ASCO43.21%2872e-70Rib7p OS=Sugiyamaella lignohabitans GN=RIB7 PE=4 SV=1
UniRef50_A0A167FQQ743.21%2877e-67Rib7p n=7 Tax=Saccharomycetales TaxID=4892 RepID=A0A167FQQ7_9ASCO
A0A1E3PT82_9ASCO43.43%2972e-69Bacterial bifunctional deaminase-reductase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_68799 PE=4 SV=1
A0A1D8PFH0_CANAL40.38%3177e-652,5-diamino-6-(Ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6341 PE=4 SV=1
RIB7_YEAST40.14%2844e-572,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RIB7 PE=1 SV=1
A0A060T111_BLAAD39.48%2718e-54ARAD1C20328p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C20328g PE=4 SV=1
Q6CA24_YARLI37.77%2782e-50YALI0D06501p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D06501g PE=4 SV=1
A0A1E4TGN4_9ASCO39.15%2582e-48Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_18801 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0215

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 284

Detailed signature matches

  1. Domain IPR024072
    Dihydrofolate reductase-like domain
    1. G3DSA:3.40.43...
    2. SSF53597 (Dihydrofo...)
  2. Domain IPR002734
    Bacterial bifunctional deaminase-reductase, C-terminal
    1. PF01872 (RibD_C)

Protein sequence

>MCA_01768_1
MSKLIPLPASIPGVIDEYLPVETNNELPFITLTYATSLDSRISAAPGVQTVISHLETKTMTHYLRYHHDAILIGVGTALA
DNPGLNCRWTPDNVENNDYSNAEEEKKLHLILPIIVDPHFKWDPRGSRLLENVKNKTGLAPYVIVREDALNDNSTGEISA
KIKALEELDGKVIKMSKSSYENGTMKWREIFSELYKEKTPSGKPIRSIMVEGGAKVINNLLDEASSLLAQDETSQPLISS
VIVTVGPVFLGSQGVCVGPITSQPRLNKVRWWTGTRDAVVCGRL

GO term prediction

Biological Process

GO:0009231 riboflavin biosynthetic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0008703 5-amino-6-(5-phosphoribosylamino)uracil reductase activity

Cellular Component

None predicted.