Protein

MCA_01765_1

Length
819 amino acids


Gene name: CDC48

Description: Cell division control protein 48

Browser: contigA:5404169-5407166-

RNA-seq: read pairs 27182, FPKM 409.6, percentile rank 93.6% (100% = highest expression)

Protein function

Annotation:CDC48Cell division control protein 48
KEGG:K13525VCP transitional endoplasmic reticulum ATPase
EGGNOG:0PGP0CDC48Cell division control protein
SGD closest match:S000002284CDC48Cell division control protein 48
CGD closest match:CAL0000177910CDC48AAA family ATPase

Protein alignments

%idAln lengthE-value
MIA_04589_194.14%8190.0MIA_04589_1
A0A0J9XGM2_GEOCN90.75%7780.0Similar to Saccharomyces cerevisiae YDL126C CDC48 ATPase involved in ubiquitin-mediated protein degradation OS=Geotrichum candidum GN=BN980_GECA16s01616g PE=3 SV=1
A0A060SYS4_BLAAD87.09%8210.0ARAD1A19316p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A19316g PE=4 SV=1
Q6C1Z3_YARLI90.21%7760.0YALI0F12155p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F12155g PE=3 SV=1
A0A1E3PEM1_9ASCO85.14%8210.0AAA ATPase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84356 PE=3 SV=1
A0A1E4TBI5_9ASCO83.54%8200.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_133764 PE=4 SV=1
CDC48_YEAST81.47%8310.0Cell division control protein 48 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC48 PE=1 SV=3
UniRef50_P2569481.47%8310.0Cell division control protein 48 n=710 Tax=Eukaryota TaxID=2759 RepID=CDC48_YEAST
Q59WG3_CANAL81.88%8280.0AAA family ATPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC48 PE=3 SV=1
A0A167D3N9_9ASCO91.92%5690.0AAA family ATPase CDC48 OS=Sugiyamaella lignohabitans GN=CDC48 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0099

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 819

Detailed signature matches

    1. SSF50692 (ADC-like)
    1. SM01073 (CDC48_N_2)
    2. PF02359 (CDC48_N)
    1. SSF54585 (Cdc48 dom...)
    1. PF02933 (CDC48_2)
    2. SM01072 (CDC48_2_2)
    1. SSF52540 (P-loop co...)
    1. SM00382 (AAA_5)
    1. PF00004 (AAA)
    1. PS00674 (AAA)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00009 (AAA)
  2. mobidb-lite (disord...)

Residue annotation

  1. Walker A motif cd0...
  2. ATP binding site c...
  3. Walker B motif cd0...
  4. arginine finger cd...
  5. Walker A motif cd0...
  6. ATP binding site c...
  7. Walker B motif cd0...
  8. arginine finger cd...

Protein sequence

>MCA_01765_1
MPEDKKPLHHNLADASGSEANKEDLTATAILRRKKKDNALIVDDATNDDNSVIALSPNTMDKLELFRGDACIVKGKKRKD
TVLVIVADEELEDGVCRINRVVRNNLRVRLGDVITIHPCPDIKYAKRISVLPIADTIEGLTGDIFEVFLKPYFVEAYRPV
RKGDLFTVRGGMRQVEFKVVEVDPAEYGIVSQDTVIHTEGDPINREDEEGNLNEVGYDDIGGVRKQMAQIRELVELPLRH
PQLFKSIGIKPPKGILMYGPPGTGKTLMARAVANETGAFFFLINGPEIMSKMAGESESNLRKAFEEAEKNAPSIIFIDEI
DSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNIVVIAATNRPNSIDPALRRFGRFDREVDVGIPDPTGRLEILRIHTK
NMKLADDVDLEAIASETHGYVGSDLASLCSEAAMQQIREKMDLIDLEEETIDAEVLDSLGVTMDNFRFALGISNPSALRE
TVVQSVNVTWDDIGGLDKIKQELKETVEYPVLHPEMYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPE
LLSMWFGESESNIRDIFDKARAAAPCVVFLDELDSIAKARGGSVGDAGGATDRVVNQLLTEMDGMNAKKNVFVIGATNRP
DQIDPALLRPGRLDQLIYVPLPDQAGRLSILKAQLRKTPLEPGLSLEEIAKSTSGFSGADLSYIVQRSAKFAIKESIEAS
IRANENAEANGEEDVEMEDPVPYITREHFEEAMKTAARSVSDAELRRYESYAAQIQASRGTLNFRFTGDSAAPGAGSGNN
ASGNEPALGGEGEDDDLYN

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005524 ATP binding
GO:0016787 hydrolase activity

Cellular Component

None predicted.