Protein

MCA_01746_1

Length
502 amino acids

Gene name: CDC37

Description: Hsp90 co-chaperone Cdc37

Browser: contigA:5362196-5363789-

RNA-seq: read pairs 2537, FPKM 62.3, percentile rank 70.1% (100% = highest expression)

Protein function

Annotation:CDC37Hsp90 co-chaperone Cdc37
KEGG:K09554CDC37 cell division cycle protein 37
EGGNOG:0PJFBCDC37hsp90 co-chaperone Cdc37
SGD closest match:S000002575CDC37Hsp90 co-chaperone Cdc37
CGD closest match:CAL0000192456CDC37Hsp90 co-chaperone Cdc37

Protein alignments

%idAln lengthE-value
MIA_04516_148.36%4884e-129MIA_04516_1
A0A0J9X7R3_GEOCN42.37%4983e-101Similar to Saccharomyces cerevisiae YDR168W CDC37 Essential Hsp90p co-chaperone OS=Geotrichum candidum GN=BN980_GECA04s06093g PE=4 SV=1
UniRef50_A0A0J9X7R342.37%4987e-98Similar to Saccharomyces cerevisiae YDR168W CDC37 Essential Hsp90p co-chaperone n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X7R3_GEOCN
A0A060T4U2_BLAAD41.61%4718e-87ARAD1C44176p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C44176g PE=4 SV=1
Q6C5F7_YARLI32.99%4857e-61YALI0E18480p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E18480g PE=4 SV=1
A0A1E3PI68_9ASCO33.53%4981e-58Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83186 PE=4 SV=1
A0A1E4TCJ2_9ASCO33.05%4753e-58Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_138894 PE=4 SV=1
CDC37_CANAL32.06%4996e-57Hsp90 co-chaperone Cdc37 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC37 PE=3 SV=1
CDC37_YEAST29.65%4794e-47Hsp90 co-chaperone Cdc37 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC37 PE=1 SV=2
A0A167FI12_9ASCO34.44%3606e-40Cdc37p OS=Sugiyamaella lignohabitans GN=CDC37 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0027

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 502

Detailed signature matches

  1. Domain IPR013855
    Cdc37, N-terminal domain
    1. SM01071 (CDC37_N_2)
    2. PF03234 (CDC37_N)
  2. Domain IPR013874
    Cdc37, Hsp90 binding
    1. SM01070 (CDC37_M_2)
    2. PF08565 (CDC37_M)
  3. Domain IPR013873
    Cdc37, C-terminal
    1. SM01069 (CDC37_C_2)
    2. PF08564 (CDC37_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. SSF101391 (Hsp90 co...)
  3. mobidb-lite (disord...)

Protein sequence

>MCA_01746_1
MVIDYSKWDKLELSDDSDIEVHPNVDKKSFIRWKQRDIHEKRERMKQNMRRLEVSNEVNTELVRRLKNLLTFAQAPDTTV
EQKQRLLSEVAYCVRIARGEGSGIKSRPVSNPQAPTYDDMIDSLYEQIQEKIEEEVKDKDTSPEAKFHMFVDMFKQHLEK
LEDVLKRELKEYDDLVEERSRHIVSEDIHTGFDTTLINEKVKEEEKKAATTKKTEKTETIEVINSPSASSSSAAQNPSVY
ESDDDVKSTPEGKKFAKIPIGDYEAVREYLHMHPSIINEREKDGLLMDAFEYGFNRDTDSVRRIVHNALILQYCATLGRN
YQAVDRFITKLATKPSEDDSASSQVKTAFSEDVEKTTNHILNRVEVLREEREKGNDGDDEEEAIIQLHFPGQKGDELTVN
IPPEDAGGDEQLEQIREAYMSLPDDLREALESKSLKKVNEVLAKIPYENAEVIVKFLDNTGIIDFIGNGVLDPEEVEKIE
AERQKLEDTKISEVDEEEKSEK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0019901 protein kinase binding

Cellular Component

None predicted.