Protein
MCA_01745_1
Length
1,421 amino acids
Gene name: SWE1
Description: Mitosis inhibitor protein kinase Swe1; homologue of S. pombe Wee1 kinase; in S. cerevisiae regulates the G2/M transition; negative regulator of the ScCdc28p kinase
Browser: contigA:5357664-5361930+
RNA-seq: read pairs 1329, FPKM 11.5, percentile rank 28.5% (100% = highest expression)
Protein function
| Annotation: | SWE1 | Mitosis inhibitor protein kinase Swe1; homologue of S. pombe Wee1 kinase; in S. cerevisiae regulates the G2/M transition; negative regulator of the ScCdc28p kinase | |
|---|---|---|---|
| KEGG: | K03114 | SWE1 | mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1] |
| EGGNOG: | 0PFTD | FGSG_10228 | inhibitor protein kinase |
| SGD closest match: | S000003723 | SWE1 | Mitosis inhibitor protein kinase SWE1 |
| CGD closest match: | CAL0000197159 | SWE1 | Mitosis inhibitor protein kinase SWE1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| Q6C389_YARLI | 48.53% | 509 | 5e-130 | YALI0F01716p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F01716g PE=4 SV=1 |
| UniRef50_Q6C389 | 48.53% | 509 | 1e-126 | YALI0F01716p n=3 Tax=Yarrowia lipolytica TaxID=4952 RepID=Q6C389_YARLI |
| MIA_03209_1 | 60.82% | 319 | 5e-119 | MIA_03209_1 |
| A0A0J9XET9_GEOCN | 48.52% | 439 | 1e-116 | Similar to Saccharomyces cerevisiae YJL187C SWE1 Protein kinase that regulates the G2/M transition by inhibition of Cdc28p kinase activity OS=Geotrichum candidum GN=BN980_GECA12s03970g PE=4 SV=1 |
| A0A060TBM6_BLAAD | 56.23% | 329 | 2e-109 | ARAD1D36278p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D36278g PE=4 SV=1 |
| A0A1E3PGF2_9ASCO | 59.85% | 269 | 5e-97 | Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_66566 PE=4 SV=1 |
| SWE1_CANAL | 43.07% | 332 | 3e-72 | Mitosis inhibitor protein kinase SWE1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SWE1 PE=1 SV=2 |
| A0A1E4TA37_9ASCO | 70.55% | 163 | 9e-78 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26922 PE=4 SV=1 |
| SWE1_YEAST | 46.89% | 273 | 4e-68 | Mitosis inhibitor protein kinase SWE1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SWE1 PE=1 SV=1 |
| A0A167E738_9ASCO | 39.60% | 298 | 9e-52 | Tyrosine protein kinase SWE1 OS=Sugiyamaella lignohabitans GN=SWE1 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.2671
Predicted cleavage: 56
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
200
400
600
800
1000
1200
1421
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
-
mobidb-lite (disord...)
Protein sequence
>MCA_01745_1 MVLRISSTADSSPSPSPHRHLAHYRSTTSPCPSNSPSPTPSPLTTRLLHPSNKQMPFHFTDTQLNTVSVVDEVHPQSIPS SASSFSSSSSTASSNSSANTTNSLPSSSTYFPNNNNNSNENNKLSSSSIFDIKSRKTNLLSQEDDYAMLDNIDTNMISTT SPLSDIHQMNQGQSKNRRPLSLSFTENEPSISKRFATSSSPSSNDSKSTTSSSSSSSTTTRALRRSTGLLNLDQASLGSP FARKPIYKSKKSQKLNPSSSSSSSNSTNSALFSSASSSSDSYSSYSFDDSNNNNNKNSKPSNMKKSQRYSLLNDSQNAKF TFSHEIPSDPISNDESVGIPQKRPHSAPFAPSKSNKSSNPFPLTAANLNSLNSSLFQFTPAKLNDSTSSSNVSKSSRPKT PFFKQPFFSPSTSSSFQPPQFSRSSQQSQFPNKDTAFKTKPLTPGNKSLEASSPILQHSPFQQGGGPSKVRKTVSSNSSN NNTTFQFHSTPKFNTNPNSLHPTHPLAFSYSLPHSSSSSPSPVPEKKIREDSPDNTPKKYNNNINNDSSFHDISSNSFNN SKSNLSKLQTSHSNHSNSFASSSNNTSFSNSNGSSTKSHFTKPPFKVNTSLESEMQYEYSTPDNNFKFAKPLQTAFMSTG LLSKRNRKNDDSSEERIVPPDTPCKKPITPVLNQHGTSSFRRSIFGHSNNSTSNILSSQSHSFDSPFSHSLPNNFFSQKP NGSNNNTSFNTSHNSSILANDQDGSFNSEINASKDLRSILNHNNSYDPDFDMDFADNDSSPNDVDFPSTPTKRDNSTDFE SSYQMSNAAFNQTQNTSFNSPYSSHTMGINIPVQASKQTSTASTITPSSFFPQRSSTPVENGKSANRIINMSTPHHKSSH WLDGSPSGISTPRTPDLVMNNVSSSSQKSTLSTSLQNASSNTINALNSNHSNGSSPLITVSDPPRTPAKTPNTSGTSGFS SLSIMSETGESSSLPFLREHFSNISVIGRGKFSYVYAVTEKNPANGMNANKYAIKRSRNPYQGPKERNRLLEEVEILRSL NQKSESDSSDDNYQDKNSSRGSLVKTTTSESISEEGRDYIVTLVDFWELNGFVFIMTEFCDNGSLDTFLEERGNFSRLDE WRVWKILVEIALGLRYIHESGFLHLDIKPANIFITFEGTLKIGDFGMATRYPTPPGIEREGDREYIAPEVLSKQIYGTPA DIFSFGLMMLEIAANIILPDNGIHWQKLRSGDLSDAGRLSSGNLCATDTEDEDDAMLGGGELLSPKYPPTTNFLQPSNNF GFNFSNSNSSNNNNGVGSSNSNGSSTSSSSSSKSNRRNKASSSSGRRSKSHHHVPIWAPKFMVNDTGALDHVVQWMLSPE PENRPSADMILRTEEAQWVDEHRKSGAVIYEGDYGPQPDSSQFFGNRGNGDHGDENWRREL
GO term prediction
Biological Process
GO:0006468 protein phosphorylation
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Cellular Component
None predicted.