Protein

MCA_01741_1

Length
1,047 amino acids


Gene name: AMN1

Description: Antagonist of mitotic exit network protein 1

Browser: contigA:5342286-5345430-

RNA-seq: read pairs 782, FPKM 9.2, percentile rank 24.7% (100% = highest expression)

Protein function

Annotation:AMN1Antagonist of mitotic exit network protein 1
EGGNOG:0QE6ZAMN1Negative regulator of the mitotic exit network (MEN), required for multiple cell cycle checkpoints (By similarity). Required for daughter cell separation and chromosome stability (By similarity). Involved in copper sensitivity (By similarity)
SGD closest match:S000000362AMN1Antagonist of mitotic exit network protein 1
CGD closest match:CAL0000192306AMN1Antagonist of mitotic exit network protein 1

Protein alignments

%idAln lengthE-value
AMN1_YARLI39.96%4631e-95Antagonist of mitotic exit network protein 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=AMN1 PE=3 SV=1
UniRef50_Q6C72539.96%4633e-92Antagonist of mitotic exit network protein 1 n=2 Tax=Yarrowia lipolytica TaxID=4952 RepID=AMN1_YARLI
A0A1E3PDV5_9ASCO37.28%4566e-89RNI-like protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_5918 PE=4 SV=1
A0A167DC56_9ASCO53.63%2481e-80Amn1p OS=Sugiyamaella lignohabitans GN=AMN1 PE=4 SV=1
A0A060T6K2_BLAAD54.69%2457e-78ARAD1C20790p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C20790g PE=4 SV=1
A0A0J9XF20_GEOCN48.59%2491e-72Similar to Saccharomyces cerevisiae YBR158W AMN1 Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability OS=Geotrichum candidum GN=BN980_GECA13s01000g PE=4 SV=1
A0A1E4TF73_9ASCO36.24%4363e-75Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_18620 PE=4 SV=1
AMN1_YEAST40.61%2291e-43Antagonist of mitotic exit network protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AMN1 PE=1 SV=1
AMN1_CANAL27.98%4864e-37Antagonist of mitotic exit network protein 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=AMN1 PE=3 SV=2
MIA_00140_127.06%1709e-06MIA_00140_1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3105

Protein family membership

None predicted.

Domains and repeats

1 100 200 300 400 500 600 700 800 900 1047

Detailed signature matches

    1. SM00367 (LRR_CC_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF52047 (RNI-like)
  2. mobidb-lite (disord...)

Protein sequence

>MCA_01741_1
MLIKRRHSSTKNQQPLSNNSLCKDQLSVPKNRQDRQQNTNKPSSSIKRYFSDGSATDNINGGSTRLNLKRRVSLFKRSFS
ITNPFQQSSSSSNSNQLTSPSIHTKNFNSAKTLQNDFAHDENEDTNQSQSDRSHLSYAFTNSESPLLPDPWHNPTNNNTN
KEKRHDDPANPPTIAFTKKLSTSTSFISNSISHSHPQSQQRSNANDTSQYYPLTPDSSTNASPIKQSFSQCSSSQNQSEE
TLLQQYTPESSPTRASSLTNSIRIASASTSSTGLQHRRQQRSISTRRKQKQKLTTTTNKTLSFSNCVSLVQNNDPETPTR
LKKPEFSIFGNSINSQNSSLSSFTQQTSSTLFSSSSTATSSSTPPLTNEQTQSSYQWPGPWAFPPGKNVTPSHLNNEEGT
TPDSSVKSTISSIVSRPTIKLVDTYNNNASNSNISLSKQEQDSSLTCDNLEDDVDGLKITESGKDALFSFPLGTTNSSST
NSCDVLSNEVSTVRVHPLLIPEIVALVIQHVDAMTPIPKELPPRRRKPMSFRHAMLLYGNREEALRAWQESRAVQPDESE
QISNRVLLECPLNEDAILNRRKKQTEPKNMMACLLVNKLWYRETVTILHSSLHFSSPDQWNKFVSSNMFKSRHRFLKESY
LNNTGSTDTQMTDVDGTQTGNSDTPLQHVGPFDINNPRLSAFFDSLDPKTLDFHAQLEVPNQAWSPRNLILHKVSHASSK
ELLESLPPWSTAKLEWLEFYTCFLLVPPPHLVAGGLLKKIALPGCPRVADPTVMMIAAQCPLLQHLDLRACALVSDNSII
QIAQKCPKLELLNVGRTIAGERITSASVDFLAKCTQITTLGMAGCHIDDWGIWELVRYRGPLLQRLSLNNCILLTNASIP
RILQYTSRLSVLELRGVVGITNMVPFIMFKRWRERLGYPPPLIEGCEVFELRMREAEWALELQITKRIFKDSLDWIYDED
DGDVDYYESPLYSLALAQASQLDDNGQRKQRLIINRQRLLHKKMYFKRKLEEEREQGQMAADAGLRRPQEIGRQSQQIIQ
RRNAITY

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.