Protein

MCA_01731_1

Length
1,851 amino acids

Gene name: IML1

Description: Vacuolar membrane-associated protein IML1

Browser: contigA:5312655-5318266-

RNA-seq: read pairs 920, FPKM 6.1, percentile rank 19.3% (100% = highest expression)

Protein function

Annotation:IML1Vacuolar membrane-associated protein IML1
KEGG:K20404DEPDC5 DEP domain-containing protein 5
EGGNOG:0PI1EIML1vacuolar membrane-associated protein iml1
SGD closest match:S000003899IML1Vacuolar membrane-associated protein IML1
CGD closest match:CAL0000199259IML1Vacuolar membrane-associated protein IML1

Protein alignments

%idAln lengthE-value
MIA_00339_146.10%8980.0MIA_00339_1
A0A0J9X648_GEOCN58.10%4634e-172Similar to Saccharomyces cerevisiae YJR138W IML1 Subunit of the SEA (Seh1-associated) complex OS=Geotrichum candidum GN=BN980_GECA02s08106g PE=4 SV=1
UniRef50_A0A0J9X64858.10%4638e-169Similar to Saccharomyces cerevisiae YJR138W IML1 Subunit of the SEA (Seh1-associated) complex n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X648_GEOCN
A0A060T9S4_BLAAD47.94%5342e-155ARAD1D14124p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D14124g PE=4 SV=1
A0A167CZG2_9ASCO52.08%4325e-140Iml1p OS=Sugiyamaella lignohabitans GN=IML1 PE=4 SV=1
A0A1E3PMZ9_9ASCO48.21%4755e-136Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50580 PE=4 SV=1
IML1_CANAL31.86%8381e-125Vacuolar membrane-associated protein IML1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=IML1 PE=3 SV=2
IML1_YARLI44.56%3954e-116Vacuolar membrane-associated protein IML1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=IML1 PE=3 SV=1
IML1_YEAST41.47%4631e-110Vacuolar membrane-associated protein IML1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IML1 PE=1 SV=1
A0A1E4TM44_9ASCO31.49%7943e-99Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17719 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0806

Protein family membership

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1400 1600 1851

Detailed signature matches

  1. Family IPR027244
    Vacuolar membrane-associated protein Iml1
    1. PF12257 (IML1)
  2. Domain IPR011991
    Winged helix-turn-helix DNA-binding domain
    1. G3DSA:1.10.10.10
    2. SSF46785 ("Winged h...)
  3. Domain IPR000591
    DEP domain
    1. PF00610 (DEP)
    2. SM00049 (DEP_3)
    3. PS50186 (DEP)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. cd04449 (DEP_DEPDC5...)
  3. mobidb-lite (disord...)

Protein sequence

>MCA_01731_1
MKSHGLKGKGISSSSIPHLKHYKQSPNKLSVQNIGIGPSSSNITLDTSDPLDIPDSKIDGDIQGPSSNELAKYLVKNIEL
NTWTHDPKVSDEDVVIDMSLLPEGTKVGDVAELRKGPNSPKFYFNVVPIPEELKKKTSDIEISLKAGPLQSILNIPSRSK
VSVRIRETHKAQADAIEIRFKDIYLTRADMWRISSRLTGKCCYRDQKITYCNSVRANICEIYRKGKKVLSGYIGTDTRII
YRSDSSRLIFLIQMSAEMWHFDEQGNIIFHKMMNSFFPEIFKRWRKQDCNHVVTIILFTRVDVSGDDKVRKHGETVGNPR
DYFRVVVDQVDINNWEEIMTTLRYEFSRFDRDILLQSTGKIVGKIAPAIKGNILEAISIATKLVSGKFRDRDLRRTGTQA
LLVTPGTGLFDVDYNAMYQTSTLLTNLEIGIDIVCLSRQPLHITPLFRFIDEKTRKVSHCVPSWLDISFWAANQNTDSQW
IPRCKIYEIQMMGVMENESSSIAIEFLPESTNETFAEMAMDQYDENVFNPGIHVDEVKPYTTEAPNIISNPQPSQIGVVL
PSSEVQAVVKPSENQAIIPPSNFQTKAQAIVESSEIDVQKTSVVANSFGPFSPANSSRSSQTSETRLNSLSDSTHSKDSY
SSGSKPRSAAEALSDQLAKQSKPKSGISSLFSSPLLRGLSTRESVDDDSKSIKEKPSSLFGISAKKSSSTLRTFKTDLDS
DEKGSVNTSKSSSREPSTKDTSSTRGTNNNIPLDSDFQSHNASLEVANAGNSRANLSTQTSISSLNDSRSNHSTRNNLFA
NALSNIPIQGLQSMFNNLHVDDSSDNEHKYHPKTDSSASSALSPITPIQSSKQSNQTSTTTPLKSIPITNNNTQKKKNTD
YEPLSDIIPGKSGWSNYSDISSHIAKNHLDRQRSISLQVNTHNKPDTPSKEQKYSTIGPSSRAEPTEKNSKQGENSGQAE
LSTTESNKEDSDYSQLPKELLEISQYLLPSNDKHGHGKMQQDLRKVKQDNTTISREVEEHSMWMTIENPSNVPQDKIIDI
SNYGRWQFVYPKMIKRRTVKWRSMISPAALPLLTFNFPSDSQLQYDFTNQDYLVLLKPESAEYNSLTEVFNEMIAVRIAL
GFQIVSKYVIAATREGEFDAKFTIETEQKEDAIGKCIYMAMGSLAQRLELKNENSVEVQIAKKKDLTTEHISAITPNVKT
RYEDRYSPITVKLLNEISTLNWNQMDQILTGNGEDVTNDPRTYRMRYVLIPVDVPQAPGLRPFGDTTQDTLNAEEMRLDG
LRKLTAMLHKGRYYTLKEKKALVRSDRPPDITFYTGSLENFLSTTYDPAIHGKQDPLIFKPTERFTRDIKLSQLAEELQS
HTGVKFENRRWHWKRHYHCFVGHDLATWLQDNFRDILNIEEAVEYGNHLMKNGLFHHVDNRHMFLDGHYFYQLAAQYADN
DHDPSSRLWFQAPSQRPKSSATDSSSLGSNQKGGVSSSHSPSTPSAKGSSGAPHHYRQRSGSIKDTILQSPSLSGQSRNT
SLSHITKDNNSIAGRNNSSCQKKKVELTRSMKYNVDPTKKSSRPEILTIHFDRVHNPEHCFQLRLEWLNTTPKLIDDAVV
NIARYTEPYGLKLVQIPLNEITKLPETNPFCSLFRCKLIIDPLDILRNRNQKNFGQISSLTRDRENSNTSVMDSQVSLID
YMADDKNDKVDALSRYNIIEKALNDDPLYYHKFILRYCDYYHDTGPISSTITDRMDVEFSWGKPTYKDFQFVHKSGLCIA
QVSNGGDYTLMINSLAVNRIEAFEQRFPREYTYGASRNSKPEALLNKFRELCQDEERLIQIFEKATQAWITEERPSSSSS
SDAYQDKQQQA

GO term prediction

Biological Process

GO:0035556 intracellular signal transduction

Molecular Function

None predicted.

Cellular Component

None predicted.