Protein

MCA_01727_1

Length
2,320 amino acids


Gene name: HIR3

Description: Histone transcription regulator 3 homolog

Browser: contigA:5300526-5307823-

RNA-seq: read pairs 1010, FPKM 5.4, percentile rank 18.2% (100% = highest expression)

Protein function

Annotation:HIR3Histone transcription regulator 3 homolog
EGGNOG:0PHS4HIR3Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation
SGD closest match:S000003901HIR3Histone transcription regulator 3
CGD closest match:CAL0000198181HIR3Histone transcription regulator 3 homolog

Protein alignments

%idAln lengthE-value
MIA_02094_146.96%15780.0MIA_02094_1
A0A0J9X539_GEOCN47.94%9240.0Similar to Saccharomyces cerevisiae YJR140C HIR3 Subunit of the HIR complex OS=Geotrichum candidum GN=BN980_GECA02s08062g PE=4 SV=1
UniRef50_A0A0J9X53947.94%9240.0Similar to Saccharomyces cerevisiae YJR140C HIR3 Subunit of the HIR complex n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X539_GEOCN
A0A060T8V9_BLAAD40.07%8610.0ARAD1D14256p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D14256g PE=4 SV=1
A0A167CZ84_9ASCO37.63%8690.0Hir3p OS=Sugiyamaella lignohabitans GN=HIR3 PE=4 SV=1
A0A1E3PM60_9ASCO33.95%6482e-109Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_41175 PE=4 SV=1
A0A1E4TC99_9ASCO28.84%8462e-95Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32663 PE=4 SV=1
HIR3_YARLI30.56%6252e-88Histone transcription regulator 3 homolog OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=HIR3 PE=3 SV=2
HIR3_CANAL27.15%8622e-78Histone transcription regulator 3 homolog OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HIR3 PE=3 SV=2
HIR3_YEAST25.63%7533e-50Histone transcription regulator 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HIR3 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0691
Predicted cleavage: 51

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 500 1000 1500 2000 2320

Detailed signature matches

Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_01727_1
MIGRGSGHCTEKKAKNFCFHHRTPTHHTSFLPQQHLLKNLFNVLVSTARSRSYTESPGNVSVTVISPVPFIEVMSNFIPI
NLYEEELIHDAEVHTRELQVEEGLELYRQALSYQQVGDRENAHKEYDKLFNLEVINLTPETGLPPSAENLKYLAFKNHGI
LLLSDIKNEKTDIDEEEYAQRVEIVVDEFSEALSYNSDDDTFLTLFAALCEQLGYYRLARLCYETIIVSPSRLKNIFDTF
ISNRFSNPQDVQTLRSLYRLCIKIKDSFTINLQSAVFKSIAQLEIESPATLPTAKLSFITPTPLSELAEYNPINPCKISI
VSYDWPSIIQALQDHAFSLTSTKSKKKLTTTDPYSISSKPSNSISFNVSTETLSKYIENVSDMNLQITEEPENKDISLQE
PTLMDLDSPSSTDAITQNSDDENKDPSQENLIEDQEACGTPNGTVGDTPAEVKAEDVQMADVDEIKNDTETEKSDDKEEK
KDDPTKETEDEKKISEDKDKEEETSKKELSDDKDATEKKDDVPDVELKDESVKTTEENPDAAQNNKKCEDRKRRRRSELS
NTGSEEPRARTSKRFKTRSTEEPASLADVDLSEDNEFFSQLSLFLSPCKFSFDSMAKIFNGQEDYPKKDLYIADFFDTLK
NDKKSPEILVLATMKNGSSKSTDTSGTSTNSSASSGSSSHQSILNQLLEGPNSIYSLPTVTRPSKLPPSPESLQFISTIN
SHHFHFQEVRVNLLRQLFGVQNPDDLSIISPVVSSVWPLSTIKSLTYLAQYCDDILQQYPKFLIKNSSKVTEFEIINEIF
ITQVILELFVNNYIGICSALKKKIGSVAKLNTKDLENKQTVLQDLYITWKSIFINLVSLVPSDSLDKLKTVLLRHKWVTF
LISKSSSDNPWDNGDDFTPIISHLENTDPDLKIEYPNFVFIPSFSLESIKSQVSRYKAISTLSEIFEDPPGLKEIQEEEE
NDPVPPPISKSKRKEDGHKSKGKSKQTAQEREKEKEKEKQREKEEEAKREKLIEERNARVADRKKRETEIRYDASIKRIG
ILERVLLPPQSRSNISSSSNESEEESSEYSAISKFLLTANLDLRLNFWNLLIADYNNVGEKLKALDGYLSIFCDIVKEFT
SEKYYNQPTDKYSSQKRRMSLLKSVYMCFDATNNLVPLITSVDDFKTIPKEKIESVMASTISILRMLYIYILYEDSIINN
VIPAPEHPDWEKCSPVIKELFVRSWYLFYYCYQKLLPQDERTLGLLTDILSIIHEQLGNRGYCCLADGIFLDLIIRELVR
IKFDDARADLVQALNCRYDLVLGGEEFHPYDHETTAIDMDKDTAFKVLPTVMDIILKRKSLAQNVLRADVKGALDEMFEA
IKFPDKSVSSISRNAFNLARTMETNVDIPFLQRCFQGVDMVDFYPTPKDVDILSSSGFYFLLSQTRMALFKVRKRTIAGH
TEDLSEAIKFLKYDLMCGDYNRFETWYQLAQGYDGLVEDDLTWDAEKITNEEFHHTTVSRQCKSIISGAIAINRLLQVGP
SPLFENTPTYQNMKKTIWPFFARMLFNASQCPMNMDAFHHVKEKIHCGPDGIYNYTPKYSLKPPSIIRVALFALNLGQKE
NPDDWYTYYLKGQMLHKLKSPPKDVLDAYLQSISCLSEKHNSHSEVILEPHYKLISNVYKYLRNKQIDQETALKYLDGTM
YKDDKISLEFDDDPDNSSVYSICLSSLVKLRAADKKKVHHRPTYRIAKIYDDAEEIYKAKEEMSTFFLLKANSKIPLQIW
KTDYERPGQHFEYTRKYTHFFITLLERTWDIEAFGFLSKCLRKFKSGMLRHQETWEFLCTCAARMLKEILEIPSRYSEKV
IAKIGHDEFYVNTAKLLAYNEEKDTPLHPMTKFLNYTAELRRLNNGFGSTAALDDLFVSLYLIIYNDFVDTVIAEEIEQE
KKEKQLREELERQKEKQRAEAPKKISVMDLLSDPITSDADSSAPSPMRSVTDTPKSAGNSKKSMTPGGKSSTPSNKSGNA
QKVRVTRRDIISRSLALLRSALHKLIATDSRMITKENTPLPTRIVSSSSYLKILNADEAEKSKLKNSSKREKEDSPEERD
LSKANGNTEDGFSNQDDKHTTKKIRLDGLLSVPGGGDEGTPSKRSKKANNGNKRQPDQPDPESNNDDLQTPNSKTTGNGN
SPNPPASGQSTPLKLQDILTPTKDDGSEATDSSDIKEINQSSFEELNKVVTPIKTEAKNKRRSNRISELLSNDDIPQPVS
TAIGTTDDSLRESSSIDQSVVSSPIPTLETNSATTEEPNSAKKRKSGGSRKSRSSTTGRNSDWYATIIGKSVDEAIEISD

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005515 protein binding

Cellular Component

None predicted.