Protein

MCA_01725_1

Length
960 amino acids

Gene name: AMD1

Description: AMP deaminase

Browser: contigA:5292095-5294978-

RNA-seq: read pairs 4565, FPKM 58.7, percentile rank 68.7% (100% = highest expression)

Protein function

Annotation:AMD1AMP deaminase
KEGG:K01490AMPD AMP deaminase [EC:3.5.4.6]
EGGNOG:0PGKEAMD1AMP deaminase
SGD closest match:S000004498AMD1AMP deaminase
CGD closest match:CAL0000182731orf19.891AMP deaminase

Protein alignments

%idAln lengthE-value
MIA_05924_176.89%6750.0MIA_05924_1
A0A0J9XJ84_GEOCN73.09%6690.0Similar to Saccharomyces cerevisiae YML035C AMD1 AMP deaminase OS=Geotrichum candidum GN=BN980_GECA20s01110g PE=3 SV=1
A0A167F162_9ASCO69.75%6910.0AMP deaminase OS=Sugiyamaella lignohabitans GN=AMD1 PE=3 SV=1
A0A060TH66_BLAAD70.94%6710.0ARAD1D28446p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D28446g PE=3 SV=1
UniRef50_A0A060TH6670.94%6710.0ARAD1D28446p n=22 Tax=Dikarya TaxID=451864 RepID=A0A060TH66_BLAAD
A0A1E3PFJ5_9ASCO59.58%8560.0AMP deaminase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83742 PE=3 SV=1
Q6C690_YARLI70.36%6580.0YALI0E11495p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E11495g PE=3 SV=1
Q5AHA6_CANAL66.62%6710.0AMP deaminase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.891 PE=3 SV=1
A0A1E4TIN5_9ASCO64.73%6550.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29987 PE=3 SV=1
AMPD_YEAST60.05%7510.0AMP deaminase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AMD1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0319

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 960

Detailed signature matches

  1. Family IPR006329
    AMP deaminase
    1. SFLDF00063 (AMP_dea...)
    2. TIGR01429
    3. PIRSF001251 (AMP_de...)
    4. cd01319 (AMPD)
  2. Domain IPR032466
    Metal-dependent hydrolase
    1. SSF51556 (Metallo-d...)
  3. Domain IPR001365
    Adenosine/AMP deaminase domain
    1. PF00962 (A_deaminase)
  4. SITE IPR006650
    Adenosine/AMP deaminase active site
    1. PS00485 (A_DEAMINASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.20.20...
  2. mobidb-lite (disord...)

Residue annotation

  1. SFLDF00063
  2. active site cd01319

Protein sequence

>MCA_01725_1
MDQLPTKPDPSDNGQTIDEARDKVADLTISRKPRSRSRNMTFDPSNSGSHGHYHHGSDMHSDFSYDGDDDDIDGLEFSKK
SMDYDDEVVVDNDTDDDDSENEDDDSDDPRRPGRLLKSSSTHFSYAEEKSMQELNAKYYALSSHSSATSIPSASSQNHHK
KPSRHDSFAKPEMVRPPPPPFIPEEASDVESRLSTSPKLTKTRSRVSSISSAIHESPLIEASSSAFSIDNFSLPKSAATA
GSISNNGAAPMSANSSTSAFGISTAPKKPNVRVPKDYKSSSYSNYLGYEQFEQQNASGAFSHDTGPEEDPIVVNELRNMY
SKVKRCLEKRRYFQDLSLQREWQNPKNQPDWKIYPPPPPPAWNPKQKQLLVSEKEKEKGEKGTVETESSTVAVESTGPNY
GKTIGIDFKFEDCEIPGKCDMVFVEDESSVFQVYENEAAAKENKPIVNVPTLRDYYIELDEVISVSSEGPSKSFAFRRLQ
YLEAKWNLYSLLNEYQETSDSKRNPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKYKMKKFPDEPVIFRDGRVLTLSQVF
ESLNLTAYDLSIDTLDMHAHKDTFHRFDKFNLKYNPIGESRLREIFLKTDNYIEGRYLAELTREVLEDLEQSKYQMAEYR
ISIYGRSESEWDKLAAWVVDNKLLSNNVRWLIQVPRLYDVYKQGGNVESFDQVVRNVFKPLFEVSIDPQSHPKLHVFLQR
VVGFDSVDDESKVGKRIHRKFPVPKLWNFTQNPPYSYYLYYLYANMTSLNNLRKRRHFNTFVLRPHAGEAGDPEHLVAAF
LTSEGINHGILLRKVPFIQYLYYLDQIGIAMSPLSNNALFLTYDKNPFYTYFKRGLNVSLSTDDPLQFAYTREPLIEEYS
VAAQIYKLSNVDMCELARNSVLQSGFEAAIKKHWLGHDYQKPGPEGNEIEKTNVPNVRLAFRNETYQHEFQLMNHYCNLK

GO term prediction

Biological Process

GO:0009168 purine ribonucleoside monophosphate biosynthetic process
GO:0032264 IMP salvage

Molecular Function

GO:0003876 AMP deaminase activity
GO:0019239 deaminase activity

Cellular Component

None predicted.