Protein

MCA_01719_1

Length
896 amino acids


Gene name: BRO1

Description: Vacuolar protein-sorting protein BRO1

Browser: contigA:5276830-5279521-

RNA-seq: read pairs 4322, FPKM 59.5, percentile rank 69.1% (100% = highest expression)

Protein function

Annotation:BRO1Vacuolar protein-sorting protein BRO1
EGGNOG:0PGNUBRO1vacuolar protein-sorting protein BRO1
SGD closest match:S000006005BRO1Vacuolar-sorting protein BRO1
CGD closest match:CAL0000196077BRO1Vacuolar protein-sorting protein BRO1

Protein alignments

%idAln lengthE-value
MIA_02050_155.96%7630.0MIA_02050_1
A0A0J9XHH9_GEOCN55.06%7610.0Similar to Saccharomyces cerevisiae YPL084W BRO1 Cytoplasmic class E vacuolar protein sorting (VPS) factor that coordinates deubiquitination in the multivesicular body (MVB) pathway by recruiting Doa4 OS=Geotrichum candidum GN=BN980_GECA17s01352g PE=4 SV=1
UniRef50_A0A0J9XHH955.06%7610.0Similar to Saccharomyces cerevisiae YPL084W BRO1 Cytoplasmic class E vacuolar protein sorting (VPS) factor that coordinates deubiquitination in the multivesicular body (MVB) pathway by recruiting Doa4 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XHH9_GEOCN
A0A060T8Q3_BLAAD45.76%7190.0ARAD1C30822p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C30822g PE=4 SV=1
A0A167FJ23_9ASCO45.30%7770.0Bro1p OS=Sugiyamaella lignohabitans GN=BRO1 PE=4 SV=1
A0A1E3PG65_9ASCO42.11%7670.0BRO1-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47539 PE=4 SV=1
A0A1E4T9X6_9ASCO42.04%7167e-179Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_125592 PE=4 SV=1
BRO1_YARLI35.58%7561e-149Vacuolar protein-sorting protein BRO1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=BRO1 PE=3 SV=1
BRO1_CANAL29.84%7915e-86Vacuolar protein-sorting protein BRO1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BRO1 PE=3 SV=2
BRO1_YEAST28.25%7222e-69Vacuolar-sorting protein BRO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BRO1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3025

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 896

Detailed signature matches

    1. PF03097 (BRO1)
    2. SM01041 (BRO1_2)
    3. PS51180 (BRO1)
    1. PF13949 (ALIX_LYPXL...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_01719_1
MRITPKIAVPLKGMSDTDWSVPLKIYFSSIYGTTDAYTEEIATLNKLRQDVRGAGKDQRGRDILYRYYAQLELLELRIPF
NESGCRINFTWQDAHSKEATTQHSIAYEKASLLFNLAAINSSIATEAEDLKLAYKAFQDAAGIYTFIFDQFLHAPSTDLT
QETTKALSKLMLAQAQESFVEQLMSNENSKPLMIAKLASGASNMYKSCSELLQNIFNDKSWGQKAWYQFSQIKTKYYLAV
SHAQQAKHYEAAGKYGDAIAHTKVAMNKLQEVSSMTIPQPFSKFSDDVSNLGDALKESLVVLEKDNDFIYHATIPSTSTI
GEIPSLDAAKPTPLSNLYKNEDVAKIIGKELFEKVIPLSVTKQTSLYSEEKAKLLRAEDEKVEIANEELASALEFLNLPA
ALSTARDNGSDILSMGSSQNVDSKVNDWAAQVSGSTPVAMAFSELDDMRRNVYSKVKEAKSLVETEAKEYFDNKSRFRER
WTQADSSLMNTGLYDDINRIESDLSNATTSDAVLRQSITQYQPQIDVLYMGPSNAQLLKEFEDAKKPSTPFSSSNSQSLL
DIDNSDDHNLPELLDDTEALLSKLNKLKKERAATFTEFKDKVHKDDISSLLVLNKKVPDIEETLFKSELAKFQPYQTRFE
QMNERQQELLKQLTYVWKQVLENPSIREKKKAKDEYTLKHNALVERYQSAFLAWKDFQAGIQKGLEFYRNMNKFTDSVLS
NAREFVNNRREESSKLSESLQNSAAQHNQDLLREQLARLSVSSSSSGSTEPSYPNLQYQQQQQQQPPLPAHPNTSSNSLY
GSAPSYQPQQPSYYPQQTTYNNPQSSYQYQAPPPPLPPQPQQQPSYGGGYPGYQQPPMQPSQYMQQPPPPPPPGQKDYSR
IPPPLPPKQPPSGGYY

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005515 protein binding

Cellular Component

None predicted.