MCA_01717_1

Protein

Length

645 amino acids

Browser: contigA:5269836-5272090+

RNA-seq: read pairs 12912, FPKM 247.0, percentile rank 90.3% (100% = highest expression)

Protein function

KEGG:	K17275	PLS1	plastin-1
EGGNOG:	0PGNK		Actin-bundling protein
SGD closest match:	S000002536	SAC6	Fimbrin
CGD closest match:	CAL0000191261	SAC6	Fimbrin

Protein alignments

	%id	Aln length
MIA_05193_1	87.94%	647	MIA_05193_1
A0A0J9X379_GEOCN	79.88%	646	Similar to Saccharomyces cerevisiae YDR129C SAC6 Fimbrin, actin-bundling protein OS=Geotrichum candidum GN=BN980_GECA02s02650g PE=4 SV=1
A0A167DTY9_9ASCO	76.27%	649	Fimbrin OS=Sugiyamaella lignohabitans GN=SAC6 PE=4 SV=1
A0A1E3PME0_9ASCO	75.19%	649	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46028 PE=4 SV=1
A0A1E4TJL6_9ASCO	72.99%	648	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_63363 PE=4 SV=1
A0A060T7A4_BLAAD	75.27%	647	ARAD1C19800p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C19800g PE=4 SV=1
Q6CE89_YARLI	72.20%	644	YALI0B17622p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B17622g PE=4 SV=2
UniRef50_Q6CE89	72.20%	644	YALI0B17622p n=157 Tax=Fungi TaxID=4751 RepID=Q6CE89_YARLI
FIMB_YEAST	71.27%	644	Fimbrin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SAC6 PE=1 SV=1
A0A1D8PPY8_CANAL	68.21%	648	Fimbrin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SAC6 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0032

Protein family membership

None predicted.

Domains and repeats

Domain
7 - 90
EF-hand domain pair (IPR011992)
165 - 185
EF-hand domain pair (IPR011992)
Domain
133 - 645
Calponin homology domain (IPR001715)

1 100 200 300 400 500 645

Detailed signature matches

IPR011992

EF-hand domain pair
1. SSF47473 (EF-hand)
  
  165 - 185
  
  SUPERFAMILY
  SSF47473 (EF-hand)
  
  7 - 90
  
  SUPERFAMILY
  SSF47473 (EF-hand)
IPR001715

Calponin homology domain
1. cd00014 (CH)
  
  292 - 394
  
  CDD
  cd00014 (CH)
  
  421 - 523
  
  CDD
  cd00014 (CH)
  
  144 - 263
  
  CDD
  cd00014 (CH)
2. PF00307 (CH)
  
  292 - 394
  
  Pfam
  PF00307 (CH)
  
  541 - 643
  
  Pfam
  PF00307 (CH)
  
  417 - 524
  
  Pfam
  PF00307 (CH)
  
  144 - 261
  
  Pfam
  PF00307 (CH)
3. G3DSA:1.10.41...
  
  412 - 528
  
  GENE3D
  G3DSA:1.10.418.10 (G3DSA:1.10.418.10)
  
  266 - 390
  
  GENE3D
  G3DSA:1.10.418.10 (G3DSA:1.10.418.10)
  
  532 - 644
  
  GENE3D
  G3DSA:1.10.418.10 (G3DSA:1.10.418.10)
  
  133 - 265
  
  GENE3D
  G3DSA:1.10.418.10 (G3DSA:1.10.418.10)
4. SSF47576 (Calponin-...)
  
  141 - 642
  
  SUPERFAMILY
  SSF47576 (Calponin-homology domain, CH-domain)
5. PS50021 (CH)
  
  415 - 525
  
  PROSITE profiles
  PS50021 (CH)
  
  538 - 645
  
  PROSITE profiles
  PS50021 (CH)
  
  291 - 394
  
  PROSITE profiles
  PS50021 (CH)
  
  143 - 263
  
  PROSITE profiles
  PS50021 (CH)
6. SM00033 (ch_5)
  
  145 - 261
  
  SMART
  SM00033 (ch_5)
  
  417 - 523
  
  SMART
  SM00033 (ch_5)
  
  293 - 392
  
  SMART
  SM00033 (ch_5)
  
  540 - 644
  
  SMART
  SM00033 (ch_5)
IPR001589

Actinin-type actin-binding domain, conserved site
1. PS00020 (ACTININ_2)
  
  497 - 521
  
  PROSITE patterns
  PS00020 (ACTININ_2)
  
  235 - 259
  
  PROSITE patterns
  PS00020 (ACTININ_2)

no IPR

Unintegrated signatures

Coil

641 - 645

COILS
Coil (Coil)
G3DSA:1.10.23...

2 - 99

GENE3D
G3DSA:1.10.238.10 (G3DSA:1.10.238.10)
mobidb-lite (disord...)

108 - 135

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative actin bin...

144E

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

145E

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

147T

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

148E

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

149F

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

152H

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

155A

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

225I

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

226N

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

229K

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

232G

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

234V

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

249H

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

250L

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

253G

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

254L

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

256W

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

257Q

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

260R

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)

261R

putative actin binding surface
144E, 145E, 147T, 148E, 149F, 152H, 155A, 225I, 226N, 229K, 232G, 234V, 249H, 250L, 253G, 254L, 256W, 257Q, 260R, 261R
CDD
cd00014 (CH)
putative actin bin...

292P

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

293P

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

295Q

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

296I

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

297L

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

300W

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

303F

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

357L

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

358D

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

361E

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

364N

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

366R

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

380K

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

381L

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

384A

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

385F

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

387A

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

388H

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

391N

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)

392T

putative actin binding surface
292P, 293P, 295Q, 296I, 297L, 300W, 303F, 357L, 358D, 361E, 364N, 366R, 380K, 381L, 384A, 385F, 387A, 388H, 391N, 392T
CDD
cd00014 (CH)
putative actin bin...

421F

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

424W

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

427S

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

487V

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

488E

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

491K

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

494K

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

496S

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

511T

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

512L

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

515A

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

516L

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

518W

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

519Q

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

522R

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

523R

putative actin binding surface
421F, 424W, 427S, 487V, 488E, 491K, 494K, 496S, 511T, 512L, 515A, 516L, 518W, 519Q, 522R, 523R
CDD
cd00014 (CH)

Protein sequence

>MCA_01717_1
MEAIKLHKKFPTVSQEDIFGLIEKFRSVDIDEKGYLDKQQAVKTLTDSGEGTYDEIRNTLKTVSVDASGRVELEDYVELV
SKLRESRQGGSTKSNTLDIPKFGNRVRSASGSGDFQPGHRHSSSANNVVVSGSSSGITHTINEEEKTEFTRHINAVLAGD
ADIGHRLPIPTDTFQIFDEARDGLILSKLINDSVPDTIDTRILNKPKQGKSLNNFTMTENANVVINSAKGIGCVVVNVHA
EDIIEGREHLILGLIWQIIRRGLLSKIDIKLHPELYRLLEDDETLEQFLRLPPEQILLRWFNFHLKAANWPRRVTNFSKD
VSDAENYTVLLNQLVPEVCTLDPLNTRDTLKRAEQVLDFAEKINARKYLTPTALVAGNPKLNLAFVAHLFNTYPGLDPIT
EDEKVEIEDFDAEGEREARVFTLWLNSLDVEPPVISLFEDLKDGTILLQAFEKVIPGSVNPRHINKRPANGEEMLRFKAV
ENTNYAVELGKQNKFSLVGIEGADITDGQKTLTLALVWQLMRRNIIETLKSLSHGGKEVTDTDILKWAQEQVRKGGKSST
IRSFKDSSLATGIFLLDVLNGLKPGYVDYDLVTPGRTEEERIANAKLAISIARKLGALIFLVPEDIIEVRSRLILSFVGA
LMALK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005515 protein binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MCA_01717_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component