Protein

MCA_01700_1

Length
1,107 amino acids

Gene name: KAP123

Description: Importin subunit beta-4

Browser: contigA:5220500-5223824-

RNA-seq: read pairs 674, FPKM 7.5, percentile rank 21.4% (100% = highest expression)

Protein function

Annotation:KAP123Importin subunit beta-4
KEGG:K20221IPO4 importin-4
EGGNOG:0QDS1KAP123importin beta-4 subunit
SGD closest match:S000000912KAP123Importin subunit beta-4
CGD closest match:CAL0000182139orf19.2489Uncharacterized protein

Protein alignments

%idAln lengthE-value
MIA_04574_164.01%11170.0MIA_04574_1
A0A0J9XKA5_GEOCN56.10%11070.0Similar to Saccharomyces cerevisiae YER110C KAP123 Karyopherin beta OS=Geotrichum candidum GN=BN980_GECA26s00252g PE=4 SV=1
UniRef50_A0A0J9XKA556.10%11070.0Similar to Saccharomyces cerevisiae YER110C KAP123 Karyopherin beta n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XKA5_GEOCN
A0A161HHC6_9ASCO48.89%11250.0Kap123p OS=Sugiyamaella lignohabitans GN=KAP123 PE=4 SV=1
A0A060TEM6_BLAAD46.77%11310.0ARAD1D16082p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D16082g PE=4 SV=1
A0A1E3PLS6_9ASCO47.09%10980.0ARM repeat-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_69586 PE=4 SV=1
A0A1D8PDL7_CANAL36.44%11250.0Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2489 PE=4 SV=1
Q6C657_YARLI36.43%10540.0YALI0E12243p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E12243g PE=4 SV=1
IMB4_YEAST33.57%11200.0Importin subunit beta-4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KAP123 PE=1 SV=1
A0A1E4TDB6_9ASCO28.37%10613e-108Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_4376 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1142

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1107

Detailed signature matches

  1. Domain IPR016024
    Armadillo-type fold
    1. SSF48371 (ARM repeat)
  2. Domain IPR011989
    Armadillo-like helical
    1. G3DSA:1.25.10.10
  3. Domain IPR001494
    Importin-beta, N-terminal domain
    1. SM00913 (IBN_N_2)
    2. PS50166 (IMPORTIN_B_NT)
    3. PF03810 (IBN_N)
  4. Domain IPR007701
    Interferon-related developmental regulator, N-terminal
    1. PF05004 (IFRD)

Protein sequence

>MCA_01700_1
MDQEFIQNLTNTLQSITAPDTDAIQRASKALQSDFYQSPIIIPALIHILQNHPEANIRQLAGVEARKLINYRWNDTADDI
RAQSKSNLLQSAIAEPNALVRHTSSRVISAIATQELQDNEWPELLPALSNSVRSSSASEREVAVYVLYTLLEADLSVLSE
HIGDLLELFSQSINDPESLQVRVSTIMALGEISSVLSSFSGQSNREVELFRSTVPSMVEVLKQVIEADDEKSVSQIFEVF
SFLLVTDATLTSKYFADLINFVLNGIAAEKQLSDEFRIPALQYLINAVRSKKMKIQALKLGPSLVSTAMDIISNYYRENE
ADLDEDDEDSLGETNPANLALQLIDTLSSHLPPVQVNAPLLEVLMKYAKAGDTAELRAGFMSLAYAAEGAPDFYATQLSV
ILPIIVAGLQSSDPQVVVAALFCLHYMGNELNESISDKHETLLPLVFNVMDNATVLKVGKNACSALSSILQSMEKRVITE
KYLDSLVPKLLHLFNTTTDLGLKSLIVTAISSAAFSSGKNFLPYFESTMKTLEPFISMTQNMMNLTEQESNLCGSVLDTV
GVIAASVGKEAFQPFVEGLVEASYKCLQTTNNRVKESAFISIGTLAKIYGEEFAVVVPKILPEVYKCLDQNEFGDLNEGD
FQIDDDNLGEDAELAEALTASSAIAMEKEYATDTLTDLICASKSQFPDIIKAISYFCSQIQHYSDGLRNSSLHGLWKSYE
TWVACDNEGAWAPGLPVSEHANEVTAAIASQVRSETLDILEQEEERVVVITICNMLTEGLKKIGPRVFLNAENLERLSTQ
INLILNKQHKCQAGVEDDVEDTELAGESAEYDEVLVDSAFDVAIQIGAALGSQFLELFSTFVVPILKYFSSSSNVERAAA
VGAIGEMVLSLKGDVTPLTEQLMKNLLHRLSDYEIEVRSNAAYGIGLLCFYSEDTETVVKSYPTILEKLQRLLKKVDKAA
KSEGGDDDNNARGLANACGCVSRMIMKHPQNVPVSDVVNVLLNRLPLTDGLEENTPVLELIFTLVKEQEPTILERRQDLV
NILAQMFEQEVQANKDLVNQTIGVDEIQFPFETDEIRSKTVELLKFLEQGQSGLVSSVPILAEKLSS

GO term prediction

Biological Process

GO:0006886 intracellular protein transport

Molecular Function

GO:0005488 binding
GO:0008536 Ran GTPase binding

Cellular Component

None predicted.