Protein
MCA_01674_1
Length
1,276 amino acids
Gene name: LEU3
Description: Regulatory protein LEU3; Zn(2)C6 fungal transcription factor
Browser: contigA:5144514-5148423+
RNA-seq: read pairs 1434, FPKM 13.9, percentile rank 32.3% (100% = highest expression)
Protein function
| Annotation: | LEU3 | Regulatory protein LEU3; Zn(2)C6 fungal transcription factor | |
|---|---|---|---|
| KEGG: | K09242 | LEU3 | transcriptional regulatory protein LEU3 |
| EGGNOG: | 0PHJM | PGUG_05411 | Transcription factor |
| SGD closest match: | S000004443 | LEU3 | Regulatory protein LEU3 |
| CGD closest match: | CAL0000199400 | LEU3 | Leucine-responsive transcriptional regulator |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9XI65_GEOCN | 55.44% | 745 | 0.0 | Similar to Saccharomyces cerevisiae YLR451W LEU3 Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation OS=Geotrichum candidum GN=BN980_GECA20s00208g PE=4 SV=1 |
| UniRef50_A0A0J9XI65 | 55.44% | 745 | 0.0 | Similar to Saccharomyces cerevisiae YLR451W LEU3 Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9XI65_GEOCN |
| MIA_04485_1 | 67.49% | 529 | 0.0 | MIA_04485_1 |
| A0A060T4K7_BLAAD | 53.63% | 647 | 0.0 | ARAD1A18414p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A18414g PE=4 SV=1 |
| A0A161HNF4_9ASCO | 49.74% | 571 | 0.0 | Leucine-responsive transcriptional regulator LEU3 OS=Sugiyamaella lignohabitans GN=LEU3 PE=4 SV=1 |
| A0A1E3PU73_9ASCO | 42.64% | 659 | 1e-154 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49041 PE=4 SV=1 |
| Q6C954_YARLI | 53.41% | 410 | 4e-150 | YALI0D13904p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D13904g PE=4 SV=1 |
| A0A1D8PND3_CANAL | 38.63% | 673 | 1e-137 | Leucine-responsive transcriptional regulator OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LEU3 PE=4 SV=1 |
| LEUR_YEAST | 39.17% | 531 | 1e-113 | Regulatory protein LEU3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LEU3 PE=1 SV=1 |
| A0A1E4TGX4_9ASCO | 28.40% | 405 | 4e-48 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57386 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0180
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
200
400
600
800
1000
1276
Detailed signature matches
no IPR
Unintegrated signatures
-
-
cd12148 (fungal_TF_MHR)
-
mobidb-lite (disord...)
Residue annotation
-
DNA binding site c...
-
Zn2+ binding site ...
Protein sequence
>MCA_01674_1 MVIKNENDFSTGGTFSNSSKDPTSNIISSVTPANKPLHPYTSNSNKNSNNNSPSSPFSIISPSGLNFEQQATQDSSNINQ ISQINSSSPSYSSLKFISHKLSDAVKTNNNNTLSNQDSVNSKNTTTTARKNKPSQDQSNNNSFRVLKFSEMASTNSTNND TAFQSSITMKMDSNSTSSVTNKFPTTVSNTISNTSSKPTLKEQSPSEMSTPPGKRIACVECRQQKVRCDAHQKYPGPCSR CSKKSLKCVLQPDFKRTYKRRRLVEVEKEIQMLRQSLESQKHETPSNIQDQEKQRMIVSAGSLLDLSNASTSTPAQATTT FKPAIAADLTTASPLSVSSTPTTKVGSRANSVATIFPPKSSSINEIPNSNSVNQKSKRSPYSDLPPPIYQRSTTPANGQY STENTPSSEASHLTPLYNNASNVSSETWQDYENGVWKCTQKSMEGVTLTPTTISNLYKEFVYKYHPILPVVDISRGPEKI YQLCPSLFWTIMATAARRYDKDGCLMQKLTPLLKTCLSEITISPVTRFAPGEGNKPFLNVASVYTVQAFIIFTLWPSVTS SLSADSSWNTVGLAMYSAIRVGLHCPWHARDFGRIKADNPIYPKISEQIRTWICCNIVSQTVATVYGFPSFTSFDASVIS ACQPNSSIEIPETIKQLMHIEHLEEEVAKTLNSNPKDHLGLSDLSERLSLIQILSGKLNELELQLEDQVDDLRKFVLLGA RVHLLSYYFLDNGGYSQLQLQKGILQVYNSALALMSHAEQAHKNDRSFFKYLPGIYVQILWQSTTIVCKVHHSPCSKFVD AAAGKTLYLSCVSLISRASIFKHDMMYRASEIMLQLWRLYRSLYKNGGYSIEGSGTLSSSSSNTSLATLSGYNQSNNDTE SGNLNNHEQEKQSLSIPAKNNAPLTVVNGYGIRIRSRMSASVFFDALWTMKEICGIRSAAPAILNQRNLEHEEEDELSVG NTAVVNEDILDRGDTLTSLNHNETQHAKNSVTFAPTPPKNVRIVPSKLLKSQNNESNQQRDSLSEQKSSSTTFSQSTESS DIIPSFRTNELDSHSSSQNIKIPLSNRHQQHSRHLDMTMNDNTSKFSVPTTVLPSSFEMSPPVTSSTSETHNGKFGLSSS SSRSLGHLIPEIDSFDNNNSHNIPDVRTPQTSNSLLNDQLYSTSIPSSAGSDSRTQINLDSDDFSLSWDAADNIVKHVSL FMSDFGFDENEGYILDPSSMSLNPSNAFMHNVLGNESNDSSGLLSSSNNNSGLNNNNNEQDIRSKNESNQSLDQIF
GO term prediction
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Molecular Function
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0008270 zinc ion binding
Cellular Component
GO:0005634 nucleus