Protein

MCA_01671_1

Length
489 amino acids

Gene name: DMA2

Description: E3 ubiquitin-protein ligase

Browser: contigA:5136320-5137864-

RNA-seq: read pairs 1125, FPKM 28.4, percentile rank 51.1% (100% = highest expression)

Protein function

Annotation:DMA2E3 ubiquitin-protein ligase
EGGNOG:0PJJ8FGSG_02564FHA domain protein
SGD closest match:S000005060DMA2E3 ubiquitin-protein ligase DMA2
CGD closest match:CAL0000178323orf19.1185Ubiquitin-conjugating protein

Protein alignments

%idAln lengthE-value
MIA_05945_180.69%2331e-133MIA_05945_1
A0A0J9XFN9_GEOCN75.21%2386e-125Similar to Saccharomyces cerevisiae YNL116W DMA2 Ubiquitin-protein ligase (E3) OS=Geotrichum candidum GN=BN980_GECA14s00956g PE=4 SV=1
UniRef50_A0A0J9XFN975.21%2381e-121Similar to Saccharomyces cerevisiae YNL116W DMA2 Ubiquitin-protein ligase (E3) n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XFN9_GEOCN
A0A060TB46_BLAAD64.66%2322e-107ARAD1D31944p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D31944g PE=4 SV=1
A0A161HFG3_9ASCO53.92%2938e-102Ubiquitin-conjugating protein DMA2 OS=Sugiyamaella lignohabitans GN=DMA2 PE=4 SV=1
A0A1E3PD24_9ASCO60.79%2273e-97SMAD/FHA domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_5490 PE=4 SV=1
Q6C175_YARLI58.18%2202e-86YALI0F18634p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F18634g PE=4 SV=1
DMA2_YEAST52.40%2292e-77E3 ubiquitin-protein ligase DMA2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DMA2 PE=1 SV=1
A0A1D8PPB7_CANAL50.43%2302e-75Ubiquitin-conjugating protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1185 PE=4 SV=1
A0A1E4T9F5_9ASCO37.02%2352e-49Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_33013 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0436

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 489

Detailed signature matches

  1. Domain IPR008984
    SMAD/FHA domain
    1. SSF49879 (SMAD/FHA ...)
  2. Domain IPR000253
    Forkhead-associated (FHA) domain
    1. PF00498 (FHA)
    2. SM00240 (FHA_2)
    3. PS50006 (FHA_DOMAIN)
  3. Domain IPR013083
    Zinc finger, RING/FYVE/PHD-type
    1. G3DSA:3.30.40.10
  4. Domain IPR001841
    Zinc finger, RING-type
    1. SM00184 (ring_2)
    2. PS50089 (ZF_RING_2)
    3. PF17123 (zf-RING_11)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.60.20...
  2. SSF57850 (RING/U-box)
  3. cd00060 (FHA)
  4. mobidb-lite (disord...)

Residue annotation

  1. phosphopeptide bin...

Protein sequence

>MCA_01671_1
MILSKLKNSLPSSSSSDNGGIKTNPEVISSASSQNSQNNINNDNNTDASRKTQQTNSILVDHQETAPLLEEGNTTPNKPH
NCINEMSNNGNISKTTTPEMFSEPKDINNKEKEKNDDNSKASSSPSSSSSSNQNPSIDNPSSSNPHSQPNTNTGQIVGTD
IMNTSSESNKQSSSESSPSETNGICQNTPIASTPPNNSPASINDNTTSNAEQGDNSQPNLLDESGTNPNTSKDTEDPYSI
RLTPYIDHSSPNPAPHIPTVERSAKEGMTIKVGRITDKNEDTKLKPEHAPVVFKSKVVSRTHAQLLVKDGQWFVQDVKSS
SGTFLNHVRLSPQYQQSQIFPLKDGDILQLGMDFRGGTEELYKCIKVRVEVNRSWQRRANTFNVNALSNLRNLSSLNPTD
LQECAICLMPVAPCQALFISPCTHAWHYKCIRPLVIKSYPHFLCPNCRAMCDLEMEIETPDLARLQSSSNSDINQNPADS
SSSVPGNGN

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005515 protein binding

Cellular Component

None predicted.